Results 181 to 190 of about 10,632,797 (342)

A Mechanism‐Based Multi‐Level Population PK/PD Model for Potassium‐Competitive Acid Blockers

open access: yesCPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 1, January 2026.
Schematic overview of a mechanism‐based, multi‐level population model for potassium‐competitive acid blockers. ABSTRACT Potassium‐competitive acid blockers (PCABs) are emerging alternatives to proton pump inhibitors for the treatment of acid‐related diseases.
Woojin Jung   +6 more
wiley   +1 more source

Sequential Event Rate Monitoring

open access: yesStatistics in Medicine, Volume 45, Issue 1-2, January 2026.
ABSTRACT Effective monitoring of event rates is essential for maintaining statistical power and study integrity in clinical trials, particularly when the primary endpoint involves time‐to‐event outcomes. We propose Sequential Event Rate Monitoring (SERM), a new and innovative approach for continuous monitoring of event rates.
Dong‐Yun Kim, Sung‐Min Han
wiley   +1 more source

A new time‐stepping strategy and boundary treatment to improve recent 2D traffic model

open access: yesZAMM - Journal of Applied Mathematics and Mechanics / Zeitschrift für Angewandte Mathematik und Mechanik, Volume 106, Issue 1, January 2026.
Abstract We show how a recently published 2D model for traffic flow can be further improved. Besides other improvements and simplifications, we present not only a method to compute the necessary time step restrictions, but also a subcycling for the inflow and outflow.
Friedemann Kemm
wiley   +1 more source

Stratigraphy of Carbonate‐Bearing Rocks at the Margin of Jezero Crater, Mars: Evidence for Shoreline Processes?

open access: yesJournal of Geophysical Research: Planets, Volume 131, Issue 1, January 2026.
Abstract Martian carbonate‐bearing rocks are compelling targets for exploration because they preserve detailed records of past aqueous processes, climate, and habitability. The Margin unit in Jezero crater is a distinct olivine‐ and carbonate‐bearing unit stratigraphically underlying the western fan, lining the inner margin of the western crater rim ...
Alexander J. Jones   +29 more
wiley   +1 more source

Propagation of solitary waves for hydrodynamical nonlinear complex model in a fractional derivative setting. [PDF]

open access: yesSci Rep
Bilal M   +6 more
europepmc   +1 more source

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