Results 11 to 20 of about 158 (138)

Increasing plasma glucose before the development of type 1 diabetes—the TRIGR study [PDF]

open access: yesPediatric Diabetes, 2021
The β-cell stress hypothesis suggests that increased insulin demand contributes to the development of type 1 diabetes. In the TRIGR trial we set out to assess the profile of plasma glucose and HbA1c before the diagnosis of clinical diabetes compared to nondiabetic children.A cohort of children (N = 2159) with an affected first-degree relative and ...
Ludvigsson, Johnny   +9 more
openaire   +7 more sources

Landslide Susceptibility Analysis by Applying TRIGRS to a Reliable Geotechnical Slope Model [PDF]

open access: yesGeosciences, 2021
This paper presents the results of a research aimed at analysing the susceptibility to shallow landslides of a study area in the Calabria region (Southern Italy).
Mariantonietta Ciurleo   +4 more
doaj   +4 more sources

Data assimilation with an improved particle filter and its application in the TRIGRS landslide model [PDF]

open access: yesNatural Hazards and Earth System Sciences, 2018
Particle filters have become a popular algorithm in data assimilation for their ability to handle nonlinear or non-Gaussian state-space models, but they have significant disadvantages.
C. Xue, G. Nie, G. Nie, H. Li, J. Wang
doaj   +4 more sources

Site-specific to local-scale shallow landslides triggering zones assessment using TRIGRS [PDF]

open access: yesNatural Hazards and Earth System Sciences, 2015
Rainfall-induced shallow landslides are common phenomena in many parts of the world, affecting cultivation and infrastructure and sometimes causing human losses.
M. Bordoni   +4 more
doaj   +7 more sources

The Impact of Geological and Rainfall Characteristics on Slope Stability Analysis in Shallow Landslide Modelling using the TRIGRS Model

open access: yesRudarsko-geološko-naftni Zbornik, 2023
West Java Province has a high potential for susceptibility to landslides. West Bandung Regency is one of the regions in West Java which has high occurrences of landslides triggered by rainfalls.
Khori Sugianti, Adrin Tohari
doaj   +1 more source

The Spatial Model using TRIGRS to determine Rainfall-Induced Landslides in Banjarnegara, Central Java, Indonesia

open access: yesJournal of the Civil Engineering Forum, 2021
Severe landslides followed by debris flow were recorded to have occurred on 12 December 2014 and discovered to have ruined infrastructures and buried hundreds of peoples in Karangkobar subdistrict of Banjarnegara district, Central Java.
Agus S Muntohar   +2 more
doaj   +1 more source

Definition of Rainfall Thresholds for Shallow Landslides in Colombian Tropical Mountainous Catchments as Debris Flow Triggering Mechanism [PDF]

open access: yesE3S Web of Conferences, 2023
As a cascade precursor of the Debris Flow phenomenon, landslides generate economic losses and human fatalities worldwide, especially in mountainous and tropical countries like Colombia.
Jaramillo-González Ricardo   +4 more
doaj   +1 more source

Efficacy and safety of abemaciclib alone and with PI3K/mTOR inhibitor LY3023414 or galunisertib versus chemotherapy in previously treated metastatic pancreatic adenocarcinoma: A randomized controlled trial

open access: yesCancer Medicine, Volume 12, Issue 20, Page 20353-20364, October 2023., 2023
Pancreatic ductal adenocarcinomas (PDAC) are characterized by frequent cell cycle pathways aberrations. This phase 2 randomized study for refractory metastatic PDAC patients showed that the CDK4/6 inhibitor abemaciclib, alone or in combination with the PI3K/mTOR LY3023414, does not improve disease control or progression‐free survival compared to ...
E. Gabriela Chiorean   +11 more
wiley   +1 more source

Outcomes reported in randomized controlled trials for mixed and non‐IgE‐mediated food allergy: Systematic review

open access: yesClinical &Experimental Allergy, Volume 53, Issue 5, Page 526-535, May 2023., 2023
Abstract Background Mixed and non‐IgE‐mediated food allergy is a subset of immune‐mediated adverse food reactions that can impose a major burden on the quality of life of affected patients and their families. Clinical trials to study these diseases are reliant upon consistent and valid outcome measures that are relevant to both patients and clinicians,
Manal Bel Imam   +11 more
wiley   +1 more source

Respiratory infections and type 1 diabetes: Potential roles in pathogenesis

open access: yesReviews in Medical Virology, Volume 33, Issue 2, March 2023., 2023
Abstract Among the environmental factors associated with type 1 diabetes (T1D), viral infections of the gut and pancreas has been investigated most intensely, identifying enterovirus infections as the prime candidate trigger of islet autoimmunity (IA) and T1D development. However, the association between respiratory tract infections (RTI) and IA/T1D is
Roy Wu   +8 more
wiley   +1 more source

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