Results 141 to 150 of about 95,645 (304)
Abstract Aim CD4 + CD25highCD127‐T regulatory cells (Tregs) remain a drug candidate for immunotherapy of type 1 diabetes. We completed three trials testing Tregs in recently diagnosed type 1 diabetes children. Here, we looked for long‐term safety and efficacy aspects important in the authorisation of this therapy.
Marta Bandura +18 more
wiley +1 more source
This paper reviews the state of the art and recent developments in thin‐film biosensors for the detection of neurotransmitters, small molecules, and biomarkers within flexible, implantable bioelectronic systems. It covers the main sensing modalities, including electrochemical, plasmonic, acoustic, and magnetic, alongside their materials, transduction ...
Massimo Mariello
wiley +1 more source
Thyroid hormone receptor β1 (TRβ) downregulation correlates with poor prognosis in clear cell renal cell carcinoma (ccRCC). Restoration of TRβ and the peroxisome proliferator‐activated receptor gamma coactivator 1‐alpha suppresses tumor progression in ccRCC through Uncoupling protein 1 mediated tumor cell “slimming” and optic atrophy 1/mitofusin 2 ...
Xiangui Meng +6 more
wiley +1 more source
Regulation of Intracellular Triiodothyronine Is Essential for Optimal Macrophage Function.
A. H. van der Spek +10 more
semanticscholar +1 more source
Natural killer cells, central to anti‐tumor defense, undergo unexpected reprogramming within the tumor microenvironment. Instead of producing IFN‐γ and TNF‐α, they elevate amphiregulin, a tumor‐promoting factor. This shift is linked to glucocorticoid receptor activity and prostaglandin signaling.
Qin Wei +8 more
wiley +1 more source
Thyroid-hormone therapy and thyroid cancer: a reassessment. [PDF]
Experimental studies and clinical data have demonstrated that thyroid-cell proliferation is dependent on thyroid-stimulating hormone (TSH), thereby providing the rationale for TSH suppression as a treatment for differentiated thyroid cancer.
BIONDI, BERNADETTE +2 more
core
A retrospective analysis of clinical features, treatment, and outcome of 29 patients with autoimmune glial fibrillary acidic protein astrocytopathy (GFAP‐A). Cerebrospinal fluid (CSF) pressure, CSF nucleated cell count, CSF protein levels, CSF chloride, serum thyroid dysfunction, and abnormal blood cytokine levels correlated with disease severity but ...
Xuewei Yang +6 more
wiley +1 more source
ABSTRACT Donepezil hydrochloride, used to treat Alzheimer's disease, is typically initiated at a low dose and titrated to minimize gastrointestinal side effects. Despite its favorable safety profile, the patient developed severe anorexia, dehydration, and electrocardiographic abnormalities.
Nobuyuki Takahashi +4 more
wiley +1 more source
Nonlinear (amplified) relationship between nuclear occupancy by triiodothyronine and the appearance rate of hepatic alpha-glycerophosphate dehydrogenase and malic enzyme in the rat. [PDF]
J H Oppenheimer +3 more
openalex +1 more source

