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Triiodothyronine: To be or not to be, that is the question [PDF]
riiodothyronine (T,) has been suggested for the treatT ment of the postcardiotomy patient for more than 5 years. The initial studies, which came from Capetown, concerned brain-dead animals and patients and suggested that this hormone might be useful in cardiac and renal transplantation if given to the donor.
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Annals of Internal Medicine, 1973
Excerpt To the editor: Shenkman and associates (1) remind us that an elevated serum triiodothyronine (T3) concentration need not mean hyperthyroidism.
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Excerpt To the editor: Shenkman and associates (1) remind us that an elevated serum triiodothyronine (T3) concentration need not mean hyperthyroidism.
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The Triiodothyronine Mitochondrial Pathway
1999Numerous data show that mitochondrial activity is hormonally regulated. Besides the influence of α-agonists, glucagon and vasopressin, several studies show that glucocorticoid, thyroid hormone, vitamin D3 and peroxisome proliferators stimulate the activity of this organelle.
Wrutniak, Chantal+3 more
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Endocrinology, 1977
The effects of administration of 3,5,3'-triiodothyronine (T3) to normal and to hypothyroid male rats upon the hepatic activity of L-triiodothyronine aminotransferase were determined using 3,5-dinitro-L-tyrosine as substrate in the assay. Initial studies in normal rats demonstrated that basal enzyme activity was highest in liver and kidney of the organs
Yee Ping Huang+3 more
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The effects of administration of 3,5,3'-triiodothyronine (T3) to normal and to hypothyroid male rats upon the hepatic activity of L-triiodothyronine aminotransferase were determined using 3,5-dinitro-L-tyrosine as substrate in the assay. Initial studies in normal rats demonstrated that basal enzyme activity was highest in liver and kidney of the organs
Yee Ping Huang+3 more
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Reverse triiodothyronine in the chicken
Life Sciences, 1977Abstract Reverse triiodothyronine (rT 3 ) which is apparently a product of 5-monodeiodination of thyroxine (T 4 ) at the periphery, was measured in 199 chickens of various strains. rT 3 was virtually absent in young birds (less than 1 week to 8 weeks of age) in marked contrast to the elevated rT 3 levels found in human and other mammalian neonates.
JA Andrada+7 more
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Triiodothyronine in Cardiac Surgery
Thyroid, 1997Thyroid hormones have profound cardiovascular effects. Chronic hypothyroidism is associated with cardiovascular abnormalities that include diminished cardiac output and increased systemic vascular resistance. Acute hypothyroidism, frequently referred to as the "euthyroid sick syndrome," is present in diverse clinical situations such as brain death ...
Andrew S. Wechsler, Timothy J. Broderick
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Triiodothyronine and Brain Excitability
Epilepsia, 1990Summary: We investigated mechanisms involved in thyroid hormone action on brain excitability. The effect of acute exposure of triiodothyronine (T3) to rat hippocam‐pal slices in vitro was studied. No significant changes could be detected in prevolley, field excitatory postsynaptic potentials (fEPSP) and population spike amplitude, while there was a ...
Erik Taubøll+3 more
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Effect of Triiodothyronine on Radiosensitivity
Nature, 1958REDUCTION in metabolic rate has been shown to reduce radiosensitivity, but the effect of an elevated metabolic rate has not been well established. Similarly, anoxia induced by various means reduces radiosensitivity. In recent years, the reverse of this phenomenon has been applied in the attempt to increase the radiation response.
Melvin L. Griem, Joseph A. Stein
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Presence of Triiodothyronine in Fowl
Nature, 1958THE observation of an unknown iodinated compound as a regular constituent of plasma and thyroid tissue of mice and rats1–3 led to the discovery of 3-5 : 3′-triiodo-L-thyronine4–7. It has been established that triiodothyronine possesses all the thyroid hormone qualities of thyroxine when tested in a large number of species8 and is more potent than ...
Claire J. Shellabarger+1 more
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The triiodothyronine suppression test
The American Journal of Medicine, 1967Abstract The results of the triiodothyronine suppression test, as performed in one hundred fifty-five patients with suspect thyroid dysfunction, are recorded. The clinical utility of this procedure as an adjunct to the laboratory diagnosis of hyperthyroidism is confirmed. The results of the present study support the validity of the criteria for normal
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