Results 101 to 110 of about 4,789,934 (292)

Trim optimization of reefer vessels

open access: yes, 2014
The influence of trim on the fuel consumption of reefer ships have been investigated. The project have been carried out at NYKCool AB, a ship operator of reefer vessels.  In the speed range 17-19 knots and deadweight percentage of approximately 70% the smallest calculated resistance is obtained for bow trims which are between -1 m and -2 m depending on
openaire   +1 more source

Boron‐Doped Nano‐Crystalline Coated Carbon Fibers for Phasic Dopamine Sensing

open access: yesAdvanced Healthcare Materials, EarlyView.
This uniform coating presents a mix of graphitic and diamond‐like carbon to create a mechanically and electrically robust alternative for the electrochemical detection of dopamine. The electrodes in this work possess the equivalent sensitivity to the state‐of‐the‐art FSCV dopamine detecting electrodes, whilst demonstrating an ability to withstand ...
Simon J. Higham   +19 more
wiley   +1 more source

Integrated optimization model in wire electric discharge machining using Gaussian process regression and wolf pack algorithm approach while machining SiCp/Al composite

open access: yesAdvances in Mechanical Engineering, 2018
To further improve prediction accuracy and optimization quality of wire electrical discharge machining of SiCp/Al composite, trim cuts were performed using Taguchi experiment method to investigate the influence of cutting parameters, such as pulse ...
Jun Ma   +6 more
doaj   +1 more source

A 3D Astrocyte Microenvironment Model Enables Rapid Ca2+‐Resolved Analysis and Therapeutic Modulation of Oxidative Neuroinflammation

open access: yesAdvanced Healthcare Materials, EarlyView.
This work presents ARC‐3D, a soft 3D model that recreates how brain support cells, called astrocytes, react to oxidative stress. The system visualizes rapid calcium changes and inflammatory signals, and shows how the drug KDS12025 can protect cells from damage. ARC‐3D offers a simple, reliable way to study early drivers of brain inflammation.
Ju‐Kang Kim   +6 more
wiley   +1 more source

Aeroelasticity study of high span ratio wing with flare folding wingtip

open access: yesXibei Gongye Daxue Xuebao
Flare folding wing-tips rely on the adaptive deformation of the structure to reduce the flight load, which can effectively simplify the control system, and has more advantages in cost and weight.
YE Bo   +4 more
doaj   +1 more source

Peptomer Linkers Enable Kinetic Control over Co‐Delivery of Multiple Chemotherapeutics

open access: yesAdvanced Healthcare Materials, EarlyView.
A key challenge in combinatorial chemotherapeutic drug delivery is independent control over release kinetics, especially with drugs of similar size and structure. Here, peptoid substitutions to proteolytically degradable peptides enabled the design of fast and slow‐releasing drug linkers.
Carolyn M. Watkins   +3 more
wiley   +1 more source

A Versatile Engineering Platform for the Fabrication of Prosthetic Venous Valves Using Electrospinning

open access: yesAdvanced Healthcare Materials, EarlyView.
Percutaneous prosthetic venous valves are fabricated by embedding stents in an electrospun matrix that extends luminally to form leaflets. The design shields leaflets from hyperplastic cells, isolates struts from blood contact, and avoids discrete anchoring points.
Dario Arcuti   +6 more
wiley   +1 more source

A Modular Bioinstructive Platform Reveals Mechanistic Insights into Additive‐Free, Topography‐Driven Osteogenesis

open access: yesAdvanced Healthcare Materials, EarlyView.
Engineered microparticle topographies direct human mesenchymal stem cell osteogenesis without biochemical additives. This osteogenic commitment is driven by canonical Hedgehog signaling and followed by temporal IGF‐II engagement. Two‐photon polymerization demonstrates spatial control, enabling the engineering of topographical gradients that pattern ...
Fatmah I. Ghuloum   +5 more
wiley   +1 more source

Medical Fabrics with Non‐Antibiotic, Supramolecular Antimicrobial Coatings: A Preventive Approach to Combat Biofilm Formation and Bacterial Dissemination

open access: yesAdvanced Healthcare Materials, EarlyView.
The study presents an antibiotic‐free strategy using medical fabrics coated with supramolecular assemblies of polyarginine and hyaluronic acid. These coatings showed strong antimicrobial and anti‐biofilm activity in vitro and in vivo, achieving major bacterial load reductions, including against MRSA.
Adjara Diarrassouba   +18 more
wiley   +1 more source

Two-Stage Global–Local Aerodynamic/Stealth Optimization Method Based on Space Decomposition

open access: yesAerospace
The design of the flying wing airfoil must consider aerodynamic stealth and trim requirements, with their coupling exacerbating the complexity of the design problem by introducing multiple local minimum points in design space.
Wei Zhang   +5 more
doaj   +1 more source

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