Draft genome sequence of <i>Pantoea anthophila</i> PGPR-34, a chrysanthemum-associated Rhizobacterium with implications for plant-microbe interactions. [PDF]
Hossain TJ.
europepmc +1 more source
De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li +23 more
wiley +1 more source
A TRIM Family-Based Strategy for TRIMCIV Target Prediction in a Pan-Cancer Context with Multi-Omics Data and Protein Docking Integration. [PDF]
Huang Y +6 more
europepmc +1 more source
Connexin43 Deficiency Leads to Ventricular Arrhythmias by Reprogramming Proline Metabolism
The study demonstrated that connexin43 (Cx43) knockout caused arrhythmic phenotype and decreased proline content in vitro and in vivo. Mechanistically, Cx43 interacts with the amino acid transporter SNAT2 (sodium‐dependent neutral amino acid transporter), and its deficiency disrupts proline transport and metabolism.
Hangying Ying +8 more
wiley +1 more source
Development and Validation of Molecularly Imprinted Polymers with Bio-Based Monomers to Adsorb Carbamazepine from Wastewater. [PDF]
Savigni E +5 more
europepmc +1 more source
3D Bioprinted Fat‐Myocardium Model Unravels the Role of Adipocyte Hypertrophy in Atrial Dysfunction
A human‐derived 3D bioprinted fat–myocardium model is developed to investigate how adipocyte hypertrophy drives atrial dysfunction in obesity. Palmitate‐induced adipocyte hypertrophy promotes adipose dysfunction that impairs atrial cardiomyocyte metabolism and electrophysiology through both paracrine and direct interactions. This platform recapitulates
Lara Ece Celebi, Pinar Zorlutuna
wiley +1 more source
A meta-analytic analysis of the acute effects of MDMA on empathy and emotion recognition in humans. [PDF]
Peled-Avron L +4 more
europepmc +1 more source
This study employs sc‐RNA sequencing, genetics, and phenotyping to systematically map the cell‐type‐specific immune responses triggered by flg22. It reveals FLS2‐dependent transcriptional reprogramming in epidermal and mesophyll cells, and uncovers crosstalk between immune and hypoxia signaling pathways.
Yaping Zhou +17 more
wiley +1 more source
Hull form optimization with a new three-dimensional deformation strategy. [PDF]
Wei D +5 more
europepmc +1 more source

