Results 61 to 70 of about 576 (158)

Donor Parameters and Platelet Yield during Plateletpheresis: A Cross-sectional Prospective Study

Journal of the Scientific Society
Background: Platelet transfusion can be life-saving in bleeding patients with thrombocytopenia or reduced platelet function. Single donor platelets (SDP) unit use is preferred due to the various advantages like reduction in transfusion-transmitted ...
Ruchi Singh, Ganga S. Pilli, Ramadevi Vivek Wani   +2 more
doaj   +1 more source

Vergleichende Untersuchung der Zellqualität mononukleärer Zellen aus Leukozytenreduktionskammern und Leukapheresaten [PDF]

, 2012
Background and Objectives Peripheral blood mononuclear cells are frequently used for dendritic cell culture in adoptive immunotherapies. The gold standard to obtain monocytes for dendritic cell therapies today is leukapheresis. Current culture efficiency
Weidinger, Thomas Michael
core   +1 more source

Transmission Electron Microscopy of Platelets FROM Apheresis and Buffy-Coat-Derived Platelet Concentrates [PDF]

, 2015
Platelet concentrates are produced in order to treat bleeding disorders. They can be provided by apheresis machines or by pooling of buffy coats from four blood donations.
Ellinger, Adolf, Neumüller, Josef, Wagner, Thomas   +2 more
core   +2 more sources

SARS-CoV-2 T Cell Response in Severe and Fatal COVID-19 in Primary Antibody Deficiency Patients Without Specific Humoral Immunity [PDF]

, 2022
Morbidity and mortality of COVID-19 is increased in patients with inborn errors of immunity (IEI). Age and comorbidities and also impaired type I interferon immunity were identified as relevant risk factors.
Bauer, Sandra, Besher, Nabeel Al, Corman, Victor M., Drosten, Christian, Gebert, Laura, Gläser, Sven, Hanitsch, Leif G., Kalus, Ulrich, Kedor, Claudia, Kleinschmidt, Malte C., Kruse, Jan M., Meisel, Christian, Meyer, Tim, Peric, Alexander, Pruß, Axel, Scheibenbogen, Carmen, Schwarz, Tatjana, Staudacher, Olga L., Steiner, Sophie, Volk, Hans-Dieter, Wald, Alexandra, Wittke, Kirsten, Zickler, Daniel   +22 more
core   +1 more source

Insulin resistance, overweight, and obesity in apheresis donors: A call to reevaluate their eligibility—A prospective cohort study

Transfusion, Volume 65, Issue 6, Page 1072-1082, June 2025.
Abstract Background Apheresis procedures and the infusion of acid‐citrate‐dextrose induce metabolic alterations that may influence glucose metabolism. Although insulin resistance (IR), overweight, and obesity are not exclusion criteria for blood donation, their impact during apheresis procedure and on post‐donation metabolic responses remains ...
Edgar Barrientos‐Galeana, Gabriela Chico‐Barba, Mari Cruz Tolentino‐Dolores, Emmanuel Fernández‐Sánchez, Rosa María Morales‐Hernández, Selene Barragán‐Montes, Maria de los Angeles Rosales‐López, Raymundo Rodríguez‐Jurado, Ángel Sebastián Quebrado‐Benítez, María‐Cristina Ramírez‐González, Heriberto López‐Martínez, Noemi Hernández‐Cruz, Jannyn Herrera‐Juárez, Karla Eugenia Bermúdez‐Ferro, Rodrigo Castillo‐Llanos   +14 more
wiley   +1 more source

Donor plasma reinfusion flushing of the LRS chamber to prevent CD4+ and CD8+ T lymphopenia

Zhongguo shuxue zazhi
Objective To explore the effectiveness of using donor plasma reinfusion to flush the leukoreduction system (LRS) chamber during the final reinfusion phase with the Trima Accel automated blood collection system in preventing the reduction of CD4+ and CD8+
Fanhai LI, Xiaowen CHEN, Linfeng ZHOU, Jieting HUANG, Xiaofan LI, Bi ZHONG, Mei XIAO, Huaqin LIANG   +7 more
doaj   +1 more source

Snorkel‐tag based affinity chromatography for recombinant extracellular vesicle purification

Journal of Extracellular Vesicles, Volume 13, Issue 10, October 2024.
Abstract Extracellular vesicles (EVs) are lipid nanoparticles and play an important role in cell‐cell communications, making them potential therapeutic agents and allowing to engineer for targeted drug delivery. The expanding applications of EVs in next generation medicine is still limited by existing tools for scaling standardized EV production ...
Madhusudhan Reddy Bobbili, André Görgens, Yan Yan, Stefan Vogt, Dhanu Gupta, Giulia Corso, Samir Barbaria, Carolina Patrioli, Sylvia Weilner, Marianne Pultar, Jaroslaw Jacak, Matthias Hackl, Markus Schosserer, Regina Grillari, Jørgen Kjems, Samir EL Andaloussi, Johannes Grillari   +16 more
wiley   +1 more source

Evaluación de la calidad del concentrado de plaquetas por aféresis Hospital Nacional Alberto Sabogal Sologuren 2020 [PDF]

, 2022
El servicio de Hemoterapia y Banco de Sangre proporciona, en forma oportuna, estos componentes sanguíneos que son las plaquetas, para ser transfundidas a aquellos pacientes que requieren trasplante de médula ósea, aquellos con diferentes hemopatías y ...
Prisse Castillo, Cynthia Silvia
core  

Platelets retain function and can be stored following disruption of human leucocyte antigens

Vox Sanguinis, Volume 119, Issue 7, Page 675-685, July 2024.
Abstract Background and Objectives Antibodies to human leucocyte antigen (HLA) Class‐I antigens can lead to refractoriness to platelet transfusion. Although this can be overcome by transfusion of HLA‐compatible platelets, they are not always available. Disruption of HLA antigens on platelets by acid treatment may be a suitable alternative when no other
April M. Davis, Renée Rawson, Gail Pahn, James Daly, Denese C. Marks   +4 more
wiley   +1 more source

Correlation of heavy metals and theirs impact to epidemiological survey in the miners blood donors and other human population [PDF]

, 2011
Introduction: Miners who are blood donors, and work in mines for lead-zinc ores are constantly exposed to heavy metals (lead, zinc and cadmium) and this aspect is expected to increase or decrease many hematological parameters.
Kamcev, Nikola, Kamceva, Gordana, Panov, Zoran, Velickova, Nevenka   +3 more
core