Targeting non-structural proteins of Hepatitis C virus for predicting repurposed drugs using QSAR and machine learning approaches [PDF]
Computational and Structural Biotechnology Journal, 2022 Hepatitis C virus (HCV) infection causes viral hepatitis leading to hepatocellular carcinoma. Despite the clinical use of direct-acting antivirals (DAAs) still there is treatment failure in 5–10% cases.
Sakshi Kamboj +4 more
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Analytic and Integrative Framework for Understanding Human Sympathetic Arterial Baroreflex Function: Equilibrium Diagram of Arterial Pressure and Plasma Norepinephrine Level [PDF]
Frontiers in Neuroscience, 2021 BackgroundThe sympathetic arterial baroreflex is a closed-loop feedback system for stabilizing arterial pressure (AP). Identification of unique functions of the closed system in humans is a challenge. Here we propose an analytic and integrative framework
Fumiyasu Yamasaki +3 more
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Trimethaphan-induced hypotension: effect on renal function [PDF]
Canadian Anaesthetists’ Society Journal, 1982 This study was designed to evaluate the effects of trimethaphan-induced hypotension on renal function in healthy young patients undergoing maxillofacial surgery. Anaesthesia was induced with thiopentone and was maintained with halothane 1.5-2.0 per cent in oxygen.
Rahim Behnia +3 more
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Hypertension in Obese Black Women is Not Caused by Increased Sympathetic Vascular Tone [PDF]
Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017 BackgroundBlack women have one of the highest prevalence rates of hypertension and obesity in the United States. We previously reported that sympathetic activation induced by obesity is a significant contributor to hypertension in white patients.
Alejandro Marinos +9 more
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Preservation of Platelet Function During Trimethaphan Infusion [PDF]
Anesthesiology, 1990 The effect of trimethaphan (Arfonad) infusion on platelet function was prospectively evaluated in 38 (n = 38) patients (28 patients receiving trimethaphan, ten control patients) undergoing elective cardiac surgery. Any patient with a positive history for the ingestion of medication known to interfere with platelet function was excluded from the study ...
Roberta Hines
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The cerebral response to sodium nitroprusside and trimethaphan controlled hypotension [PDF]
Canadian Anaesthetists’ Society Journal, 1975 Cette etude avait pour but d’etablir la marge de securite associee a l’emploi d’hypotension controllee en neuro-chirurgie, hypotension produite soit avec du Trimethaphan ou du Nitro-prussiate. Ces agents par leur action sur la resistance vasculaire permettent de diminuer la pression de perfusion cerebrale (C.P.P.) tout en maintenant le flot sanguin ...
W. W. Stoyka, H. Schutz
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A Comparison of the Cardiovascular Effects of Sodium Nitroprusside and Trimethaphan [PDF]
Survey of Anesthesiology, 1977 In dogs anesthetized with pentobarbital-chloralose, cardiac output and blood flows of four regional vascular beds (superior mesenteric, left renal, left circumflex coronary and left femoral) were continuously monitered with electromagnetic flowmeters. Arterial blood pressure and heart rate were also measured.
Hsueh Hwa Wang +2 more
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Prolonged Apnea Following Trimethaphan and Succinylcholine [PDF]
Anesthesiology, 1979 THOMAS J. POULTON +2 more
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HORMONE CHANGES WITH NITROPRUSSIDE OR TRIMETHAPHAN [PDF]
Anesthesiology, 1980 Geoffrey A. Lane +3 more
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