Results 121 to 130 of about 19,593 (221)
Ligase‐Catalyzed Transcription and Reverse Transcription of XNA by T3 DNA Ligase
Current Protocols, Volume 6, Issue 1, January 2026.Abstract The growing utility of xeno‐nucleic acids (XNAs) lies in their ability to extend the reach of genetic chemistry beyond the limits imposed by natural polymers. XNAs, with their diverse chemical backbones, resist enzymatic degradation and yet retain the capacity for sequence‐defined information, and have found broad applications in biotechnology.
Natalie Khamissi +2 more
wiley +1 more source
Ecology and Evolution, Volume 16, Issue 1, January 2026.Based on morphological and chloroplast phylogenomic analyses, we describe Aletris medogensis as a new species endemic to the eastern Himalayas. Comparative genomics revealed structural variations, hypervariable markers, and signatures of positive selection in key genes, providing robust evidence for species delimitation and insights into the ...
Xiong Li +5 more
wiley +1 more source
PLoS Computational Biology, 2015 Conformational polymorphism of DNA is a major causative factor behind several incurable trinucleotide repeat expansion disorders that arise from overexpansion of trinucleotide repeats located in coding/non-coding regions of specific genes.
Noorain Khan +2 more
doaj +1 more source
Molecular Therapy: Nucleic Acids, 2019 Huntington’s disease (HD) is a currently incurable and, ultimately, fatal neurodegenerative disorder caused by a CAG trinucleotide repeat expansion within exon 1 of the huntingtin (HTT) gene, which results in the production of a mutant protein that forms
Freja K. Ekman +5 more
doaj +1 more source
Ecology and Evolution, Volume 16, Issue 1, January 2026.The initial comparative plastome analysis of 10 Artocarpus species in China lays the groundwork for regional evolutionary research. Investigated of inverted repeat (lR) boundary variations, particularly the incomplete duplication of the ycf1 gene, elucidating mechanisms underlying genomic divergence.
Ru‐Li Zhang +8 more
wiley +1 more source
Ecology and Evolution, Volume 16, Issue 1, January 2026.In this study, we report the first de novo assembled chloroplast genome of Verbesina encelioides, a member of the tribe Heliantheae within the subfamily Asteroideae of Asteraceae. ABSTRACT Verbesina encelioides (Cav.) Benth. & Hook.f. ex A.Gray (Asteroideae, Asteraceae) is a widespread annual herb native to southwestern North America that has ...
Rushan Yan +7 more
wiley +1 more source
The Importance of Clinical Acumen for Prenatal Diagnosis in an Increasingly Technological World
Prenatal Diagnosis, EarlyView.
Teresa N. Sparks, Lyn S. Chitty
wiley +1 more source
Ecology and Evolution, Volume 16, Issue 1, January 2026.The study presents the first complete chloroplast genome of Lycium shawii (PQ824997.1) spanning 155,936 bp and contains 128 genes (84 protein‐coding genes, 36 tRNAs, and eight rRNAs). Nucleotide diversity analysis highlighted atpI, rbcL, and accD as hypervariable loci suitable for DNA barcoding. Molecular dating analysis revealed that L.
Manal Mohammed Ahmed Asiri +8 more
wiley +1 more source
Correction: A CTG trinucleotide repeat expansion in the gene encoding junctophilin-3 is associated with Huntington disease–like 2 [PDF]
, 2002 S Holmes +26 more
openalex +1 more source
European Journal of Neurology, Volume 33, Issue 1, January 2026.Clinical exome sequencing (CES) was performed on 108 Spanish patients with suspected hereditary spastic paraparesis (HSP), using a virtual 129‐gene panel and HPO‐based variant filtering. A molecular diagnosis was achieved in 53% of cases, with 21 causative genes identified (8 novel variants), SPAST (AD) and SPG7 (AR) being the most frequent genetic ...
Lidón Carretero‐Vilarroig +8 more
wiley +1 more source