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Controlled trial of lovastatin combined with an open-label treatment of a parent-implemented language intervention in youth with fragile X syndrome. [PDF]

, 2020
BackgroundThe purpose of this study was to conduct a 20-week controlled trial of lovastatin (10 to 40 mg/day) in youth with fragile X syndrome (FXS) ages 10 to 17 years, combined with an open-label treatment of a parent-implemented language intervention (
Abbeduto, Leonard +10 more
core

The Preparation of Liposomes Derived From Mixed Micelles of Lecithin Added by Sodium Cholate, Followed by Dialysing Using Hemoflow High Flux F60S [PDF]

, 2004
Liposomes are used for drug carriers meaning that drugs are incorporated in the membrane or the vesicle of the liposomes. In this study, liposomes were prepared from mixed micelles, consisting of phosphatidylcholine, without or with cholesterol
Purwaningsih, E. H. (Erni), Schubert, R. (Rolf) +1 more
core +1 more source

The Amino Terminus of the Yeast F_1-ATPase β-Subunit Precursor Functions as a Mitochondrial Import Signal [PDF]

, 1986
The ATP2 gene of Saccharomyces cerevisiae codes for the cytoplasmically synthesized beta-subunit protein of the mitochondrial F1-ATPase. To define the amino acid sequence determinants necessary for the in vivo targeting and import of this protein into ...
Douglas, Michael G. +5 more
core

Regulation of reactivated elongation in lysed cell models of teleost retinal cones by cAMP and calcium. [PDF]

, 1986
Teleost retinal cones elongate in the dark and contract in the light. In isolated retinas of the green sunfish Lepomis cyanellus, cone myoids undergo microtubule-dependent elongation from 5 to 45 micron. We have previously shown that cone contraction can
Ackland, N, BURNSIDE, Beth, Gilson, C
core +1 more source

Ultrastructural localization of adenosine triphosphatase activity in lymphocytes activated in vitro by phytohaemagglutinin [PDF]

, 1982
The ultrastructural localization of Ca 2+, Mg2+ -activated ATPase was studied in phytohaemagglutinin activated lymphocytes and in normal unstimulated lymphocytes. Cells, fixed in paraformaldehyde-glutaraldehyde, were incubated in a medium containing 3 mM
Cuschieri, Alfred, Kharbat, B.A., Mughal, S. +2 more
core

Elongation factor 2 in cancer: a promising therapeutic target in protein translation

Cellular & Molecular Biology Letters
Aberrant elongation of proteins can lead to the activation of oncogenic signaling pathways, resulting in the dysregulation of oncogenic signaling pathways.
Xuechao Jia +4 more
doaj +1 more source

Functional conservation and divergence of arabidopsis VENOSA4 and human SAMHD1 in DNA repair

Heliyon
The human deoxyribonucleoside triphosphatase (dNTPase) Sterile alpha motif and histidine-aspartate domain containing protein 1 (SAMHD1) has a dNTPase-independent role in repairing DNA double-strand breaks (DSBs) by homologous recombination (HR). Here, we
Raquel Sarmiento-Mañús +7 more
doaj +1 more source

Myosin Adenosine Triphosphatase