Results 71 to 80 of about 51,803 (231)
Allosteric Regulation of RNA Affinity by Motif V‐VI Coupling in West Nile Virus NS3 Helicase
ABSTRACT The rise of flaviviral diseases, including West Nile virus (WNV), presents a growing threat to global public health and underscores the urgent need for new therapeutic strategies. The non‐structural protein 3 helicase (NS3h) of the Orthoflavivirus genus, including WNV, is essential for viral replication and a promising antiviral target ...
Priti Roy, Martin McCullagh
wiley +1 more source
Localized Activation of Bending in Proximal, Medial and Distal Regions of Sea-Urchin Sperm Flagella [PDF]
Spermatozoa from the sea urchin, Colobocentrotus atratus, were partially demembranated by extraction with solutions containing Triton X-100 at a concentration which was insufficient to solubilize the membranes completely.
Brokaw, C. J., Gibbons, I. R.
core
Preparation of Neurospora crassa mitochondria [PDF]
The fungus Neurospora crassa represents a eukaryotic cell with high biosynthetic activities. Cell mass doubles in 2-4 hr during expone ntial growth , even in simple salt media with sucrose as the sole carbon source. The microorgani sm forms a mycelium of
Jacki +11 more
core +2 more sources
Abstract Objectives Vonoprazan, a potassium‐competitive acid blocker, provides more rapid, potent, and durable elevations in gastric pH than proton pump inhibitors in adults and may be a treatment option for adolescents and children with gastroesophageal reflux disease (GERD).
Darcy J. Mulford +6 more
wiley +1 more source
Background Copper export protein ATP7A is important for maintaining copper homeostasis. Recent studies have shown that copper transporters are also involved in the transport of platinum.
Li Zhuang-hua +9 more
doaj +1 more source
Histochemical studies of adenosine triphosphatase activity of liver cells exposed to ribonuclease [PDF]
It has been revealed that ribonuclease (RNase) can penetrate into living cells and inhibits amino acid incorporation into proteins resulting in the suppression of protein synthesis and growth of living cells.
Hayashi, Kenji, Kimoto, Tetsuo
core +1 more source
Crystallization of Chlorella deoxyuridine triphosphatase [PDF]
Deoxyuridine triphosphatase (dUTPase) is a ubiquitous enzyme that has been widely studied owing to its function and evolutionary significance. The gene coding for the dUTPase from the Chlorella alga was codon-optimized and synthesized. The synthetic gene was expressed in Escherichia coli and recombinant core Chlorella dUTPase (chdUTPase) was purified ...
Badalucco, Laura +4 more
openaire +2 more sources
Decoding the Role of Caveolin‐1 in Morphological Diversity and Self‐Renewal of Breast Cancer Cells
The silence of caveolin‐1 (Cav‐1) reproduced the morphological evolutionary behaviour of cancer cells, which is similar to the epithelial‐mesenchymal transition process. And Cav‐1 dependent morphological changes could affect cancer cell self‐renewal capacity through maintaining the morphological stability.
Shun Li +14 more
wiley +1 more source
Solving the Structure of eIF2 Bound to eIF2B Using Cryogenic Electron Microscopy [PDF]
Translation begins when initiation factor-2 (eIF2) delivers methionyl initiator tRNA (Met-tRNAi) to the ribosome. The exchange of GDP bound to eIF2 for GTP is a prerequisite to binding Met-tRNAi and is mediated by a second initiation factor, eIF2B ...
Kenner, Lillian
core
The light and shadow of senescence and inflammation in cardiovascular pathology and regenerative medicine [PDF]
Recent epidemiologic studies evidence a dramatic increase of cardiovascular diseases, especially associated with the aging of the world population. During aging, the progressive impairment of the cardiovascular functions results from the compromised ...
Cavarretta, Elena +9 more
core +4 more sources

