Results 51 to 60 of about 903 (247)
Advanced Science, EarlyView.The membrane‐active peptide Pep19‐2.5 reduces harmful inflammation by blocking activation of the NLRP3 inflammasome at trans‐Golgi network membranes. By targeting key membrane interactions, Pep19‐2.5 suppresses inflammatory IL‐1β production and alleviates allergic airway inflammation in mice, leading to reduced immune cell infiltration and improved ...
Jonas Engelhardt +16 more
wiley +1 more source
Invasão paraguaia no Rio Grande do Sul: aspectos navais [PDF]
Navigator, 2015 The Paraguayan invasion in the Brazilian province of Rio Grande do Sul was planned in detail . Paraguayan President Francisco Solano Lopez personally coordinated the actions that the troop held .
Luiz Augusto Rocha do Nascimento
doaj
Brothers must stand together. “Americanism” during the Paraguayan War in Argentina (1865-1870)
Iberoamericana. América Latina - España - Portugal, 2019 This paper analyzes the representations of “Americanism” in the Argentinian political intellectual debate during the Paraguayan War. In contrast to the popular revisionist approach, we find that the “American” ideal appears in a weak way during the ...
María Victoria Baratta
doaj +1 more source
Cancer‐Associated BCL‐2 Mutants Reveal Mechanisms Towards Venetoclax Resistance
Advanced Science, EarlyView.Venetoclax (VEN) resistance in chronic lymphocytic leukemia arises from diverse BCL2 mutations. We map mechanisms contributing to VEN resistance across common BCL‐2 variants. G101V and D103Y reduce drug binding and increase sequestration of pro‐apoptotic proteins. V156D blocks VEN allosterically.
Jonas Aufdermauer +9 more
wiley +1 more source
Adaptive Responses of Tropical Crops: A Multi‐Scale Omics Integrated Perspective
Advanced Science, EarlyView.Tropical crops integrate genomic, morphological, physiological, and ecological adaptations to thrive under extreme and variable environments. This review highlights how natural selection, domestication, and breeding shape stress resilience, resource‐use strategies, and productivity in sugarcane, banana, cassava, rubber and oil palm, offering new routes
Peilin Wang +11 more
wiley +1 more source
A Fortaleza de Humaitá: entre o mito e a realidade [PDF]
Navigator, 2018 The Humaitá Fortress was the most important military engineering work of the Republic of Paraguay in the López Period (1841-1870). Although since the time of Doctor Jose Gaspar Rodríguez de Francia, in the period of Independence (1811-1840), there had ...
Eduardo Nakayama
doaj
American Journal of Community Psychology, EarlyView.Abstract In Canada, precarious migration is largely invisibilized. Nonetheless, b/ordering greatly affects people's realities by limiting access to social rights. In Quebec, migrants with precarious status (MPS) do not have access to healthcare, although Quebec has a “universal” healthcare coverage.
Émilie Pigeon‐Gagné +3 more
wiley +1 more source
Augusto Roa Bastos's Trilogy as Postmodern Practice
Studies in 20th & 21st Century Literature, 1998 Augusto Roa Bastos's most recent novel, El fiscal (1993), completes the author's trilogy on the "monotheism of power," which the novel constitutes in conjunction with the prior works Hijo de hombre (1960) and Yo el Supremo (1974). These novels form
Helene C. Weldt-Basson
doaj +1 more source
International Forum of Allergy &Rhinology, EarlyView.ABSTRACT Background Chronic rhinosinusitis (CRS) is one of the most common manifestations of eosinophilic granulomatosis with polyangiitis (EGPA), often preceding the diagnosis of systemic vasculitis by several years. The sinonasal presentation of EGPA typically resembles CRS with nasal polyps (CRSwNP), making it clinically indistinguishable from those
Alisha Sharma +12 more
wiley +1 more source
Nuevo mundo - Mundos Nuevos, 2011 In the first half of the 1910s, Paraguay and Uruguay developed common initiatives of commemorations, most of which were officially sanctioned. Generally, these initiatives were linked to events of the shared history of these countries.
María Laura Reali
doaj +1 more source