Results 181 to 190 of about 200,653 (263)

Machine learning-guided optimization of triple agonist peptide therapeutics for metabolic disease. [PDF]

Front Bioinform
Wong A, Guduri S, Chen T, Patel K.
europepmc   +1 more source

RNA‐Micelles as Self‐Assembling Structures for Efficient Co‐Delivery of Synergistic siRNA and Nucleoside Analogues to Treat CRC Lung Metastasis

Advanced Functional Materials, EarlyView.
Two kinds of self‐assembled RNA micelles were used to co‐deliver synergistic siRNA and nucleoside analogues for the treatment of colorectal cancer lung metastases. Near‐complete elimination of lung cancer metastases was confirmed in an orthotopic lung metastasis model constructed using human colorectal cancer lung metastases patient surgical samples to
Kai Jin, Piotr Rychahou, Daniel W. Binzel, B. Mark Evers, Peixuan Guo   +4 more
wiley   +1 more source

Triple autoimmune overlap syndrome of the liver: a rare case of concomitant PBC, PSC, and AIH. [PDF]

Future Sci OA
Hassen H, Dahmani W, Bedoui G, Sakly S, Souilem E, Ghdiri Y, Jaziri H, Ben Slema A, Brahem A, Elleuch N, Ksiaa M.   +10 more
europepmc   +1 more source

Bio‐Orthogonally Crosslinked Supramolecular Polymer Bottlebrush Hydrogels for Long‐Term 3D Cell Culture

Advanced Functional Materials, EarlyView.
Fibrous benzenetrispeptide (BTP) hydrogels, fabricated via strain‐promoted azide‐alkyne cycloaddition (SPAAC) crosslinking, form robust, bioinert networks. These hydrogels can support 3D cell culture, where cell viability and colony growth depend on the fiber content.
Ceren C. Pihlamagi, David Pretzel, Peer Nölte, Kourosh Rezaei, Ulrich S. Schubert, Johannes C. Brendel   +5 more
wiley   +1 more source

CDK8 Inhibition Increases E2F1 Transcriptional Activity and Promotes STAT3-Dependent Suppression of Mcl-1 in Triple-Negative Breast Cancer Cell Line MDA-MB-468. [PDF]

Int J Mol Sci
Do S, Li S, Xiong R, Spear JM, Lu Z, Chan WK, Russu WA.   +6 more
europepmc   +1 more source

Gram‐Scale Production of Iron Oxide Rubik‐Cube Nanoparticles: New Tools for the Clinical Translation of Magnetic Hyperthermia and Magnetic Particle Imaging

Advanced Functional Materials, EarlyView.
This work reports the first gram‐scale solvothermal synthesis of ‘Rubik's cube’ nanoparticles—cubic, dendritic multicore structures with tuneable sizes and exceptional magnetic heating performance. Featuring iron oxide single‐domain character, with low coercivity fields, high magnetization, and strong MPI signals, they enable viscosity‐independent ...
Giusy M. R. Rizzo, Niccolò Silvestri, Nabila Jarmouni, Helena Gavilán, Hamza Yakubu, Daniel Arenas‐Esteban, Sara Bals, Paola Parlanti, Mauro Gemmi, Ross Clark Prado, Anna Cristina S. Samia, Verónica Salgueiriño, Teresa Pellegrino   +12 more
wiley   +1 more source

Integrating time-dependent diffusion MRI and intravoxel incoherent motion for predicting NPI and molecular subtypes in breast cancer. [PDF]

BMC Med Imaging
He L, Liu Z, Yang L, Qin Y, Luo Z, Zhang Y, Song X, Mao W, Wu D, Ai T.   +9 more
europepmc   +1 more source

Tuning the Selectivity of the CO2 Reduction Reaction by Means of Synergistic Interactions in the Cu, Ag, Ce System

Advanced Functional Materials, EarlyView.
Multi‐metal Cu─Ce─Ag nanoparticles harness synergistic interactions to drive efficient electrochemical CO2 reduction reaction toward C2+ products at high current densities. Ag enhances CO production, Ce modulates Cu oxidation states, and together they boost *CO coverage and local pH to enhance C─C coupling, enabling record C2+ yields with suppressed ...
Nini Zhang, Muhammad Adib Abdillah Mahbub, Bashir Eid, Thomas Quast, Jian Zhang, Ridha Zerdoumi, Xin Wang, Sabine Seisel, Wangcheng Zhan, Wolfgang Schuhmann   +9 more
wiley   +1 more source

nNav1.5 mRNA Expression in Triple Negative and Non-Triple Negative Breast Cancer Patients Treated at Hospital Pakar Universiti Sains Malaysia. [PDF]

Asian Pac J Cancer Prev
Ahmad Sukri AF, Suhaimi NS, Mohd Adzemi ER, Mohd Azlan M, Yahya MM, Wan Abdul Rahman WF, Mokhtar NF.   +6 more
europepmc   +1 more source

Broadband, Flexible, Skin‐Compatible Carbon Dots/Graphene Photodetectors for Wearable Applications

Advanced Functional Materials, EarlyView.
Broadband, flexible photodetectors integrating nitrogen‐rich carbon dots with single‐layer graphene on plastic substrates are demonstrated. A biocompatible chitosan–glycerol electrolyte enables efficient low‐voltage gating and on‐skin operation. The devices exhibit ultraviolet‐to‐near‐infrared response, mechanical robustness under bending, and verified
Nouha Loudhaief, Petr Rozhin, Ilaria Bertuol, Ali Raza, Leonardo Viti, Subhankar Roy, Enrico Cavarzerani, Luca Sbuelz, Matteo Brilli, Andrea Serinolli, Jacopo Nicoletti, Riccardo Piccoli, Sebastián Castilla, Simone Dal Zilio, Enrique Rodríguez‐Castellón, Miriam Serena Vitiello, Maurizio Selva, Flavio Rizzolio, Alvise Perosa, Giovanni Antonio Salvatore, Domenico De Fazio   +20 more
wiley   +1 more source