Results 211 to 220 of about 216,465 (259)

Endosomal Escape of siRNA Polyplexes: A Molecular Dynamics Perspective on Underlying Mechanisms

Advanced Functional Materials, EarlyView.
Molecular dynamics simulations reveal distinct endosomal escape mechanisms of siRNA nanoparticles, ranging from electrostatic membrane attachment to hydrophobic membrane fusion. Hydrophobic residues and anionic endosomal lipids emerge as key determinants of membrane disruption, linking molecular interactions to experimental delivery performance and ...
Katharina M. Steinegger, Min Jiang, Florian Belger, Fabian Link, Benjamin Winkeljann, Olivia M. Merkel   +5 more
wiley   +1 more source

Engineering of the High-Precision Cas12m Dual Base Editor-Loaded Virus-like Particles for A-to-G and C-to-T Conversions. [PDF]

Genes (Basel)
Aliev T, Imatdinov A, Prudnikova E, Imatdinov I.   +3 more
europepmc   +1 more source

Programming Neuromorphic Plasticity Through Ionic and Electronic Coupling in Organic Electrochemical Transistors

Advanced Functional Materials, EarlyView.
Neuromorphic plasticity in OECTs is governed by the post‐stimulus evolution of coupled ionic and electronic states. Semiconductor chemistry and morphology, electrolyte composition and interfaces, and device architecture regulate ion injection, transport, confinement, and release, shifting responses from rapidly relaxing STP to metastable memory and ...
Inho Lee, Hyoik Jang, Ji Hwan Kim, Jonghyun Won, Namhee Kim, Wonseok Shin, Giwon Lee, Eunho Lee, Daegun Kim, Sungjun Park   +9 more
wiley   +1 more source

Dual recognition drives site-directed G-quadruplex stabilization: Oligonucleotide design in G4 ligand-oligonucleotide conjugates. [PDF]

Mol Ther Nucleic Acids
Abrahamsson A, Khwaja S, Chaudhari N, Vertueux S, Berner A, Aasumets K, Kumar C, Stietz L, Baladi T, Dahlén A, Wanrooij S, Chorell E.   +11 more
europepmc   +1 more source

The <i>COL4A3</i> c.3418+1G>T variant causes exon 39 skipping in minigene assays: functional and exploratory structural analyses. [PDF]

Front Genet
Ban X, Wang Y, Guo Y, Wang J, Sun H, He P, Wang M, Tang X, Fan Q.   +8 more
europepmc   +1 more source

(Hetero)Adamantane Synthesis: A Triple Alkylation Reaction. [PDF]

J Org Chem
McCallum T, Rohe S, Morin M, Su HY, Shields SWJ, Tanveer K, Mamone M, Zindy N, Chamelot G, Allis DG, Hill AJ, Drew M.   +11 more
europepmc   +1 more source

A capsid hinge region in European hepatitis E virus links mutations to genotype, virion surface properties, and environmental circulation. [PDF]

Appl Environ Microbiol
Kasmi S, Sautrey G, Hartard C, Quilès F, Bailly J-L, de Rougemont A, Jeulin H, Duval RE, Gantzer C, Schvoerer E.   +9 more
europepmc   +1 more source

Is there a correlation between signal intensity ratio of 3T MRI and molecular subtypes of breast cancer? [PDF]

Radiol Oncol
Tao Y, Chao H, Ren Y, Zheng W, Chen Y, Du L, Li H, Cui F.   +7 more
europepmc   +1 more source

Human SRD5A1 as a case of gene expression indel-resistance in triple-coding region. [PDF]

Genome Biol
Yordanova MM, Tierney JAS, Meiklejohn KA, Slattery C, Świrski MI, Baranova-Gurvich M, Engels M, Ting O, Prakash A, Tjeldnes H, Mudge JM, Loughran G, Vizcaíno JA, Andreev DE, Baranov PV.   +14 more
europepmc   +1 more source