Results 101 to 110 of about 1,290,443 (295)
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
Super Jordan triple systems and Kantor triple systems
, 2019 We introduce the notion of $ \epsilon $-super Jordan triple systems(sJTS), a supersymmetric generalization of Jordan triple systems which includes them as well as the class of N=6 3-algebras as particular cases. The Tits-Kantor-Koecher construction for Kantor triple systems(KTS) and for $ \epsilon $-super Jordan triple systems is established and ...
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Molecular Oncology, EarlyView.This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon +9 more
wiley +1 more source
Sensors, 2018 This study proposes two models for precise time transfer using the BeiDou Navigation Satellite System triple-frequency signals: ionosphere-free (IF) combined precise point positioning (PPP) model with two dual-frequency combinations (IF-PPP1) and ...
Rui Tu +4 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source
Dynamical Systems on Spectral Metric Spaces [PDF]
, 2010 Let (A,H,D) be a spectral triple, namely: A is a C*-algebra, H is a Hilbert space on which A acts and D is a selfadjoint operator with compact resolvent such that the set of elements of A having a bounded commutator with D is dense.
Bellissard, Jean V. +2 more
core +1 more source
Molecular Oncology, EarlyView.Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat +8 more
wiley +1 more source
TARİHİN ÇAĞLARA AYRILMASINDA “ÜÇLÜ SİSTEM” ve TÜRK-İSLÂM TARİHİ’NİN ÇAĞ TAKSİMİ MESELESİ
Turkish History Education Journal, 2014 German Scholar Cellarius, in periodization of history grounded on Christian “trinity” based system, secularized this system and reached a final level. After him, Triple Periodic System became a de facto rule and used until today.
Necmettin Alkan
doaj +1 more source
Discrete Mathematics, 1974 AbstractA t-design (λ, t, d, n) is a system B of sets of size d from an n-set S, such that each t subset of S is contained in exactly λ elements of B. A t-design is indecomposable (written IND(λ, t, d, n)) if there does not exist a subset B ⊆ B such that B is a (λ, t, d, n) for some λ, 1 ⩽ λ < λ. A triple system is a (λ; 2, 3, n).
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