Results 51 to 60 of about 1,290,443 (295)

Multiple ETS family transcription factors bind mutant p53 via distinct interaction regions

FEBS Letters, EarlyView.
Mutant p53 gain‐of‐function is thought to be mediated by interaction with other transcription factors. We identify multiple ETS transcription factors that can bind mutant p53 and found that this interaction can be promoted by a PXXPP motif. ETS proteins that strongly bound mutant p53 were upregulated in ovarian cancer compared to ETS proteins that ...
Stephanie A. Metcalf, Nicholas F. Downing, Kaitlyn M. Mills, Samuel C. Metcalfe, Alexander E. Kritzer, Lindsey D. Mayo, Peter C. Hollenhorst   +6 more
wiley   +1 more source

Graph factorization, general triple systems, and cyclic triple systems

Aequationes Mathematicae, 1981
In this self-contained exposition, results are developed concerning one-factorizations of complete graphs, and incidence matrices are used to turn these factorization results into embedding theorems on Steiner triple systems. The result is a constructive graphical proof that a Steiner triple system exists for any order congruent to 1 or 3 modulo 6.
STANTON, R.G., Goulden, I.P.
openaire   +1 more source

The Algol triple system spatially resolved at optical wavelengths

, 2010
Interacting binaries typically have separations in the milli-arcsecond regime and hence it has been challenging to resolve them at any wavelength. However, recent advances in optical interferometry have improved our ability to discern the components in ...
Armstrong, Buscher, Csizmadia, ESA, Evans, Hartkopf, Heintz, Hill, Hummel, Kovalevsky, Labeyrie, Lindegren, Prieur, Prieur, Shepherd, Shepherd, Söderhjelm, van Moorsel   +17 more
core   +1 more source

Studies of multiple stellar systems - III. Modulation of orbital elements in the triple-lined system HD 109648 [PDF]

, 2000
The triple-lined spectroscopic triple system HD 109648 has one of the shortest periods known for the outer orbit in a late-type triple, 120.5 days, and the ratio between the periods of the outer and inner orbits is small, 22:1.
Aarseth, Bailyn, Batten, Baumgardt, David W. Latham, Fekel, Ford, Gatewood, Gray, Guillermo Torres, Holman, Jha, Krymolowski, Latham, Latham, Mathieu, Mayor, Mazeh, Mazeh, Mazeh, Mazeh, Mazeh, Mazeh, Mazeh, Nordström, Robert P. Stefanik, Saar, Saurabh Jha, Stefanik, Söderhjelm, Tokovinin, Tokovinin, Tsevi Mazeh, Upgren, Upgren, Zahn, Zucker, Zucker   +37 more
core   +3 more sources

Conserved structural motifs in PAS, LOV, and CRY proteins regulate circadian rhythms and are therapeutic targets

FEBS Letters, EarlyView.
Cryptochrome and PAS/LOV proteins play intricate roles in circadian clocks where they act as both sensors and mediators of protein–protein interactions. Their ubiquitous presence in signaling networks has positioned them as targets for small‐molecule therapeutics. This review provides a structural introduction to these protein families.
Eric D. Brinckman, Anna E. Lester, Brian D. Zoltowski   +2 more
wiley   +1 more source

Generalized derivations of Lie triple systems

Open Mathematics, 2016
In this paper, we present some basic properties concerning the derivation algebra Der (T), the quasiderivation algebra QDer (T) and the generalized derivation algebra GDer (T) of a Lie triple system T, with the relationship Der (T) ⊆ QDer (T) ⊆ GDer (T) ⊆
Zhou Jia, Chen Liangyun, Ma Yao
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

FEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5′ untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
Hernán Romo‐Casanueva, Ariann E. Mendoza‐Martínez, P. Abril Medina‐Flores, Carlos Campero‐Basaldua, Alexander DeLuna, Soledad Funes   +5 more
wiley   +1 more source

Lagrange versus Lyapunov Stability of Hierarchical Triple Systems: Dependence on the Mutual Inclination between Inner and Outer Orbits

The Astrophysical Journal, 2023
While there have been many studies examining the stability of hierarchical triple systems, the meaning of “stability” is somewhat vague and has been interpreted differently in previous literatures. The present paper focuses on “Lagrange stability,” which
Toshinori Hayashi, Alessandro A. Trani, Yasushi Suto   +2 more
doaj   +1 more source

Detection Probability of a Low-Mass Planet for Triple Lens Events: Implication of Properties of Binary-Lens Superposition

, 2010
In view of the assumption that any planetary system is likely to be composed of more than one planet, and the multiple planet system with a large mass planet has more chance of detailed follow-up observations, the multiple planet system may be an ...
Beaulieu, Bennett, Bennett, Bennett, Bond, Bond, Charbonneau, Chauvin, Chung, Dong, Gaudi, Gaudi, Gaudi, Gould, Gould, Griest, Han, Han, Han, Han, Han, Han, Heon-Young Chang, Ida, Janczak, Kayser, Kennedy, Kubas, Laughlin, Mao, Mayor, Mayor, Mayor, Myeong-Gu Park, Paczyński, Rattenbury, Rhie, Rivera, Schneider, Sumi, Udalski, Wambsganss, Witt, Wolszczan, Yee, Yoo, Yoon-Hyun Ryu   +46 more
core   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

FEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka, Yuxi Liu, Stefano Maggi, Debnath Ghosal, Jue Wang, Prashant P. Damke, Stephen D. Carter, Wei Zhao, Sukhithasri Vijayrajratnam, Joseph P. Vogel, Carrie L. Shaffer, Grant J. Jensen   +11 more
wiley   +1 more source