Autopolyploidization‐Induced Chromatin Remodeling Regulates Leaf Size Variation in Brassica rapa
This study demonstrates that monoploid, diploid, and autotetraploid Brassica rapa lines derived from the same genome exhibit distinct leaf morphology. Ploidy changes remodel chromatin accessibility and histone modifications to regulate gene expression, while key transcription factors BrGRF13 and BrARF11 control leaf size and polarity, driving ...
Haoyuan Dong +17 more
wiley +1 more source
Multiplexing of visual-auditory signals in a predominantly auditory brain region. [PDF]
Schmehl MN, Chen Y, Tokdar ST, Groh JM.
europepmc +1 more source
Red‐light‐activated Ir1 overcomes hypoxia tolerance and adapts to the immunosuppressive tumor microenvironment, converting immunologically cold tumors into inflamed hot microenvironments. This conversion is driven by synergistic induction of immunogenic cell death through coordinated ferroptosis‐necroptosis pathways and spatiotemporally controlled ...
Long‐Bo Yu +8 more
wiley +1 more source
A Comparative Evaluation of Super-Resolution Methods for Spectral Images Using Pretrained RGB Models. [PDF]
Shokoohi N +3 more
europepmc +1 more source
Art-Historical Dataset with Structured Metadata and Iconographic Triplets from Wikidata
Schneider, Stefanie +5 more
openalex +1 more source
Fluorinated Carnitine Derivatives as Tools to Visualise Carnitine Transport and Metabolism
Fluorinated carnitines, fluoromethyl carnitine (FMC) and [18F]fluoromethyl carnitine ([18F]FMC), are synthesised and established as powerful probes to interrogate carnitine biology. The multimodal detection facilitated by fluorine labelling, including 19F NMR, mass spectrometry, and positron emission tomography imaging, allowed for visualisation of ...
Richard S. Edwards +8 more
wiley +1 more source
Best therapeutic approach in metastatic hormone-sensitive prostate cancer based on disease volume: a systematic review and network meta-analysis. [PDF]
Di Costanzo F +21 more
europepmc +1 more source
A Closed‐Loop Hybrid Discovery System of Type I Photosensitizers for Hypoxic Tumor Therapy
The work developed a closed‐loop hybrid discovery system to rationally design and predict high‐performance Type I PSs for hypoxic tumor therapy. 664 Potential candidates are identified from a dataset through a support vector machine (SVM) classification model, and two candidates are experimentally verified as Type I PSs, which highlighted the potential
Xia Ling +9 more
wiley +1 more source
Molecular Studies of <i>TCF4</i> Gene and Correlation with Late-Onset Fuchs Endothelial Corneal Dystrophy in the Greek Population: A Novel Cost-Effective Diagnostic Algorithm. [PDF]
Petri N +7 more
europepmc +1 more source

