Results 171 to 180 of about 76,303 (316)

NuSAP Safeguards Centriole Integrity to Mediate CEP57‐CEP152 Torus Recruitment for Proper Engagement

Advanced Science, EarlyView.
This study reveals a novel role for the microtubule stabilizer NuSAP at centrioles. NuSAP depletion destabilizes the centriole's tubulin structure, causing premature disengagement, PCM defects, and mis‐localization of the CEP57‐CEP63‐CEP152 complex. By reinforcing centriole architecture, NuSAP enables early CEP57 loading and initiates a newly proposed ...
Shiyu Zhang, Zemin Jiang, Qiaoyun Yang, Hong Zheng, Minghao Wang, Chennianci Zhu, Lih‐Wen Deng, Karen Carmelina Crasta, Yih‐Cherng Liou   +8 more
wiley   +1 more source

PRDM1+ Malignant Cells Mediate an Immunosuppressive Landscape and Resistance to Neoadjuvant Chemoradiotherapy and Immunotherapy in Esophageal Squamous Cell Carcinoma

Advanced Science, EarlyView.
Integrated scRNA‐seq, scTCR‐seq analysis, and functional assays identify PRDM1+ malignant epithelial cells with hyper lipid peroxidation characteristics that demonstrate reduced responsiveness to the nICRT treatment. Principal factor PRDM1 activates cysteine metabolism genes to modulate lipid peroxidation (an intrinsic cellular pathway related to ...
Dijian Shen, Rui Li, Yong She, Xuefei Liu, Yuanyang Huang, Yongling Ji, Keying Chen, Zhengbo Song, Runzhe Chen, Xuan Li, Qi Zhao, Qixun Chen, Ming Chen   +12 more
wiley   +1 more source

Comparing Outcomes and Risks of Multiple Gestations: Assisted versus Spontaneous Conceptions. [PDF]

Int J Womens Health
Alarfaj RK, Alwahhabi A, Alshalan R, Alabdulkareem Y, Alabdulkareem D, Alkharouf F.   +5 more
europepmc   +1 more source

cDC1 Subtype‐Specific In Vivo Targeting of Liposomes

Advanced Science, EarlyView.
Dendritic cells, particularly the cDC1 subtype, offer a promising target for drug delivery via liposomes due to their pivotal role in immune regulation, allowing for amplified therapeutic responses. Herein, we show an integration of physicochemical characterization and cell experiments to achieve effective in vivo cDC1 targeting through anti‐CLEC9A ...
Maximilian Schaaf, Michael Fichter, Lin Jian, Felicia Schön, Carina Jung, Paul Schneider, Kai Speth, Ana Mateos‐Maroto, Volker Mailänder, Kaloian Koynov, Svenja Morsbach, Katharina Landfester   +11 more
wiley   +1 more source

Accelerating SCF Orbital Optimization with S-GEK/RVO: Efficient Subspace Compression and Robust Convergence. [PDF]

J Chem Theory Comput
Fdez Galván I, Weßling D, Lindh R.
europepmc   +1 more source

Enhancing Quantum Dot Photovoltaic Efficiency Through Defect Passivation and Triplet Energy Transfer with 9‐Anthracenecarboxylic Acid [PDF]

Eon Ji Lee, Gayoung Ham, Sunhee Yun, Hyung Ryul You, Taeyeong Yong, Gayoung Seo, Wonjong Lee, Hyeon Soo, Jin Young Park, H. Kim, Soo‐Kwan Kim, Younghoon Kim, Jongchul Lim, Minjun Kim, Hyojung Cha, Jongmin Choi   +15 more
openalex   +1 more source

A theory ofnonverticaltriplet energy transfer in terms of accurate potential energy surfaces: The transfer reaction from π,π* triplet donors to 1,3,5,7-cyclooctatetraene [PDF]

, 2004
Luis Manuel Frutos, Obis Castaño, José L. Andrés, Manuela Merchán, A. Ulises Acuña   +4 more
openalex   +1 more source

Stimuli‐Responsive Supramolecular Biomaterials for Cancer Theranostics

Advanced Science, EarlyView.
The ultimate goal of cancer theranostics is to get imaging agents and therapeutic cargo to tumor sites when and where they are required. “Smart” systems should be developed. This review discusses the characteristics of physiological stimuli, types and action modes of external stimuli, construction approaches and working principles, as well as ...
Wenting Hu, Binglin Ye, Guocan Yu, Feihe Huang, Zhengwei Mao   +4 more
wiley   +1 more source

Alliance A022104/NRG-GI010: The Janus Rectal Cancer Trial: a randomized phase II/III trial testing the efficacy of triplet versus doublet chemotherapy regarding clinical complete response and disease-free survival in patients with locally advanced rectal cancer [PDF]

Janet Alvarez, Qian Shi, Arvind Dasari, Julio García‐Aguilar, Hanna Sanoff, Thomas J. George, Theodore S. Hong, Greg Yothers, Philip Philip, Garth D. Nelson, Tareq Al Baghdadi, Olatunji B. Alese, Wini Zambare, Dana M. Omer, Floris S. Verheij, Aron Bercz, Min Jung Kim, James J. Buckley, Hannah Williams, Manju George, Reese Garcia, Phuong Gallagher, Eileen M. O’Reilly, Jeffrey A. Meyerhardt, Jamie Crawley, Ardaman Shergill, Natally Horvat, Paul B. Romesser, William A. Hall, J. Joshua Smith   +29 more
openalex   +1 more source

Prophylactic cerclage in the management of triplet pregnancies [PDF]

, 2004
Andrei Rebarber, Ashley S. Roman, Niki Istwan, Debbie Rhea, Gary Stanziano   +4 more
openalex   +1 more source