Results 111 to 120 of about 97,595 (299)

Maternal, childhood and adolescent influences on Leydig cell functional capacity and circulating INSL3 concentration in young adults: Importance of childhood infections and body mass index

open access: yesAndrology, EarlyView.
Abstract Background The constitutive Leydig cell hormone insulin‐like peptide 3 (INSL3) is considered a good estimate of the adult Leydig cell functional capacity and appears to remain relatively consistent throughout adult male life, only gradually declining into old age.
Richard Ivell   +3 more
wiley   +1 more source

Benefits of Maternal Choline Supplementation on Aged Basal Forebrain Cholinergic Neurons (BFCNs) in a Mouse Model of Down Syndrome and Alzheimer’s Disease

open access: yesBiomolecules
Down syndrome (DS), stemming from the triplication of human chromosome 21, results in intellectual disability, with early mid-life onset of Alzheimer’s disease (AD) pathology.
Melissa J. Alldred   +8 more
doaj   +1 more source

Assessing a Model for a Complex Systemic Disorder—The Value of Male Mice With a Supernumerary X Chromosome for Klinefelter Syndrome Research

open access: yesAndrology, EarlyView.
ABSTRACT Introduction Direct experimental investigation of Klinefelter syndrome (KS) in patients is limited because the syndrome manifests heterogeneously and affects multiple organ systems. Studying KS therefore requires a model that captures this complexity as accurately as possible while still permitting controlled experimental manipulation ...
Fariba Saadati, Joachim Wistuba
wiley   +1 more source

Predicting Respiratory Complications for Day Case Paediatric Adenotonsillectomy

open access: yesANZ Journal of Surgery, EarlyView.
ABSTRACT Objectives To assess the effectiveness of a pre‐operative triaging model for paediatric adenotonsillectomy in identifying risk of early post‐operative respiratory complications, in order to propose an evidence‐based triaging model for day‐case paediatric adenotonsillectomy.
Clemente Chia   +3 more
wiley   +1 more source

Improved risk stratification for placenta‐mediated complications through the use of mid‐gestational uterine artery Doppler: A retrospective cohort study

open access: yesActa Obstetricia et Gynecologica Scandinavica, EarlyView.
Mid‐gestational uterine artery Doppler refines first‐trimester screening risk stratification for placenta‐mediated complications. Sequential assessment reclassifies women into four combined groups, identifying a distinct highest‐risk subgroup (H1H2) with over 40% adverse outcomes.
Christina Ammari   +5 more
wiley   +1 more source

Diagnóstico molecular de cromosomopatías fetales en Costa Rica Molecular Diagnosis of Fetal Chromosomal Defects in Costa Rica

open access: yesActa Médica Costarricense, 2009
Justificación y objetivos: En Costa Rica, el diagnóstico de anomalías cromosómicas fetales se realiza solo mediante el análisis citogenético convencional de cromosomas obtenidos de cultivos celulares.
Wendy Malespín-Bendaña   +2 more
doaj  

The Swedish National Pediatric Cataract Register (PECARE): Coexisting systemic disorders 2007–2023

open access: yesActa Ophthalmologica, EarlyView.
Abstract Purpose To analyse the frequency and type of coexisting systemic disorders in children operated on for cataract in Sweden. Methods Data were retrieved from the Swedish National Pediatric Cataract Register (PECARE) for children operated between January 1, 2007, and December 31, 2023 (n = 975), including follow‐ups at age 1, 2, 5 and 10 ...
David Wackerberg   +9 more
wiley   +1 more source

Concomitant t(8;21) and trisomy 4 in a patient with Acute Myeloid Leukemia (AML) [PDF]

open access: yes, 2010
The t(8;21)(q22;q22) is a frequently occurring aberration in acute myeloid leukemia (AML) (18-20%) and usually correlate with French-America-British (FAB) M2 subtype.
Chang KM,   +4 more
core  

Daunorubicin‐45 Vs. Daunorubicin‐60 for Induction in Intermediate‐Age Patients of AML: Results From a Randomized Trial

open access: yesCancer Science, EarlyView.
Daunorubicin dose escalation from 45 to 60 mg/m2 provides no clinical benefit for AML patients aged 55–65. A dose of 45 mg/m2 should remain the preferred regimen for this population. ABSTRACT Daunorubicin dose optimization remains crucial for AML treatment.
Chunlin Zhou   +15 more
wiley   +1 more source

Incidence of Obesity Among Mentally Retarded Children [PDF]

open access: yes, 1985
An international survey of professionals in the field of mental retardation was conducted to determine significant research priorities in the education of students with mild retardation.
Fox, Robert A.   +3 more
core   +1 more source

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