Results 91 to 100 of about 55,941 (207)

Tablet Assessment of Cognition in Down Syndrome: Comparison of Researcher and Caregiver Administration

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Identifying flexible and rigorous methods to administer assessments in Down syndrome research is critical for limiting participation burden. Tablet assessments have the potential to be presented remotely, but consistency between researcher and caregiver administrations is unknown.
Emily K. Schworer, Emily K. Hoffman, Anna J. Esbensen   +2 more
wiley   +1 more source

Age Differences in Emotion Regulation Among Individuals With Down Syndrome

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Although there is clear evidence that individuals with Down syndrome (DS) experience difficulties in identifying and interpreting emotions, there is limited research on emotional regulation in this population. Furthermore, many studies of individuals with DS focus on group comparisons against typically developing children, with few ...
Sophie Kowalski, Caron A. C. Clark
wiley   +1 more source

A Prospective Cohort Study with Diagnostic Accuracy Assessment for Sensitivity of Nuchal Translucency and Nasal Bone in First-Trimester Screening for Trisomy 21 and Association with Pregnancy Outcomes

Life and Science
Objective: To determine the sensitivity and specificity of nuchal translucency and nasal bone for detecting trisomy 21 and other poor fetal outcomes. Study Design: A prospective cohort study with diagnostic accuracy assessment.
Shumaila Khawaja Khail, Abeera Choudry, Viqar-U-Nisa Ashraf, Asifa Siraj, Rabia Qasim, Amna Fareed   +5 more
doaj   +1 more source

Prevalence of Mental Disorders in Parents With Intellectual Disabilities: A Systematic Review

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Research indicates that an increasing number of adults with intellectual disabilities (IDs) are becoming parents. Parents with ID face multiple challenges that increase their mental health risks. In order to ensure better detection and tailored care for parents with ID, this systematic review aimed to summarise the prevalence of ...
Sonya Rudra, Louise Marston, Angela Hassiotis, Giovanni Boido, Mary Baginsky, Claire A. Wilson   +5 more
wiley   +1 more source

Elevated Nocturnal CO2 and Autonomic Dysfunction in Children With Down Syndrome

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Sleep‐disordered breathing (SDB) frequently complicates Down syndrome (DS). Beyond upper airway obstruction, emerging evidence suggests an autonomic nervous system (ANS) dysfunction affecting CO2 regulation. The aim of this study was to investigate nocturnal gas exchanges in children with DS and compare them to what has been ...
Jessica Taytard, Segolène Falquero, Sophie Denamur, Pierre‐Yves Boelle, Karl Leroux, Harriet Corvol, Aimé Ravel, Clotilde Mircher, Jeanne Toulas, Emmanuelle Prioux, Marie‐Anne Caillaud, Guillaume Aubertin, Hervé Walti   +12 more
wiley   +1 more source

Analysis of Second Trimester Maternal Quadruple Screening Test for Trisomy 21 and Trisomy 18

Zdravniški Vestnik, 2014
Background: The second trimester quadruple screening test for foetal chromosomal abnormalities has been carried out in Slovenia since 2006. Our objective was to analyse the quadruple test results, define sensibility and specificity, the positive and ...
Katja Bricelj, Maja Vuković, Ivan Verdenik, Joško Osredkar, Ksenija Geršak   +4 more
doaj  

Cell‐free DNA test for fetal chromosomal abnormalities in multiple pregnancies

Acta Obstetricia et Gynecologica Scandinavica
Introduction This study aimed to report the screening performance of cell‐free DNA (cfDNA) testing for chromosomal abnormalities in twins, triplets, and vanishing twin pregnancies.
Angel H. W. Kwan, Maria Mar Gil, Shuwen Xue, Yvonne K. Y. Kwok, Doris Lau, Joanna Fung, Andrea Chan, Kwong Wai Choy, Tak Yeung Leung, Liona C. Poon   +9 more
doaj   +1 more source

Informant‐Reported Mobility‐Related Observations Associated With Subsequent Dementia in Adults With Intellectual Disability: A Longitudinal Cohort Study

Journal of Intellectual Disability Research, EarlyView.
ABSTRACT Background Dementia is more prevalent in individuals with intellectual disability (ID) than in the general population. Identifying signs of dementia is important to access relevant evaluations, treatment and care. The role of mobility in identifying dementia in ID is not well understood.
Karl Olsson, Barry Karlsson, Ylva Cedervall, Hanna Bozkurt Åhman   +3 more
wiley   +1 more source

Characterizing primary transcriptional responses to short term heat shock in Down syndrome.

PLoS ONE
Heat shock stress induces genome-wide changes in transcription regulation, activating a coordinated cellular response to enable survival. We noticed many heat shock genes are up-regulated in blood samples from individuals with trisomy 21.
Joseph F Cardiello, Jessica Westfall, Robin Dowell, Mary Ann Allen   +3 more
doaj   +1 more source

+21 or trisomy 21 [PDF]

Atlas of Genetics and Cytogenetics in Oncology and Haematology, 2011
openaire   +1 more source