Results 41 to 50 of about 55,941 (207)

Referral patterns and patient characteristics in pediatric feeding disorder care at a multidisciplinary outpatient clinic

JPGN Reports, EarlyView.
Abstract Objectives Pediatric feeding disorders (PFDs) are increasingly prevalent in the United States. Limited research has examined referral characteristics for outpatient feeding programs. This study analyzes patient referral characteristics based on referral patterns, patient demographics, and treatment interventions. Methods A retrospective cohort
Edward Tannenbaum, Riad Rahhal, Linda Cooper‐Brown, Willow Cover, Adam Vaske, Dina Al‐Zubeidi   +5 more
wiley   +1 more source

Transcriptional consequences of trisomy 21 on neural induction

Frontiers in Cellular Neuroscience
IntroductionDown syndrome, caused by trisomy 21, is a complex developmental disorder associated with intellectual disability and reduced growth of multiple organs. Structural pathologies are present at birth, reflecting embryonic origins.
José L. Martinez, José L. Martinez, Jennifer G. Piciw, Jennifer G. Piciw, Jennifer G. Piciw, Madeline Crockett, Isabella A. Sorci, Nikunj Makwana, Carissa L. Sirois, Yathindar Giffin-Rao, Anita Bhattacharyya, Anita Bhattacharyya   +11 more
doaj   +1 more source

The Incidence of Associated Anomalies in Children with Congenital Duodenal Obstruction—A Retrospective Cohort Study of 112 Patients

Children, 2022
Background: Duodenal obstruction (DO) is a congenital anomaly that is highly associated with other anomalies, such as cardiac anomalies and trisomy 21. However, an overview of additional anomalies and patient-specific risk factors for cardiac anomalies ...
Adinda G. H. Pijpers, Laurens D. Eeftinck Schattenkerk, Bart Straver, Petra J. G. Zwijnenburg, Chantal J. M. Broers, Ernest L. W. Van Heurn, Ramon R. Gorter, Joep P. M. Derikx   +7 more
doaj   +1 more source

Characterizing Post Tonsillectomy Respiratory Complications in Patients Under Three

The Laryngoscope, EarlyView.
ABSTRACT Objective To characterize the postoperative respiratory complications in children < 3 years old who underwent tonsillectomy. Methods Retrospective chart review of patients < 3 years old at time of tonsillectomy. Demographics, comorbidities, polysomnography results, intraoperative factors, and postoperative respiratory complications ...
Nathan E. Lu, Fendi Obuekwe, Amber D. Shaffer, Marina V. Rushchak, Amanda L. Stapleton   +4 more
wiley   +1 more source

Pediatric Epiglottopexy: A Scoping Review of Indications, Techniques, Outcomes, and Complications

The Laryngoscope, EarlyView.
This scoping review synthesizes the indications, techniques, outcomes, and complications of pediatric epiglottopexy across 24 studies comprising 371 patients from ten countries. Epiglottopexy, most often performed alongside supraglottoplasty, was associated with favorable respiratory and swallowing outcomes, though the evidence base consists ...
Karim Estephan, Mathieu Bergeron
wiley   +1 more source

“Biomarkers of immune hyperactivation and inflammation are elevated in pregnancies complicated by fetal Trisomy-21”

The Journal of Maternal-Fetal & Neonatal Medicine
Objective To compare interferon-linked/inflammatory biomarkers (neopterin, indoleamine-2,3-dioxygenase [IDO], and YKL-40) in maternal serum and amniotic fluid between Trisomy-21 and chromosomally normal pregnancies.Methods This prospective case-control ...
Ilgin Turkcuoglu, Selcan Sinaci, Rauf Melekoglu, Songul Unuvar, Nesibe Zeyveli Celik, Seyma Yasar, Busra Berfin Polat   +6 more
doaj   +1 more source

Hemophagocytic lymphohistocytosis in trisomy 21: successful treatment with interferon inhibition

Pediatric Rheumatology Online Journal, 2022
Background Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening condition of immune dysregulation primarily driven by the cytokine interferon gamma.
Allison Guild, Jordan Fritch, Sachit Patel, Adam Reinhardt, Melissa Acquazzino   +4 more
doaj   +1 more source

SLC7A6OS Founder Mutation: A Rare Cause of Progressive Myoclonus Epilepsy Dated to 1100 Years Ago

Movement Disorders, EarlyView.
Abstract Background SLC7A6OS c.191A>G is a rare, autosomal recessive cause of progressive myoclonus epilepsy (PME). The c.191A>G variant, first discovered in two families from Türkiye and Portugal, was recently identified in three additional probands from the USA, all of Puerto Rican ancestry.
Bronwyn E. Grinton, Colin A. Ellis, Mered Parnes, Laina Lusk Stripe, Jacob E. Munro, Laure Mazzola, Pamela P. McDonnell, Betül Baykan, Volkan Taşdemir, Mariam Hull, Krystal Sully, Sara Cabet, Anna‐Elina Lehesjoki, Nerses Bebek, Melanie Bahlo, Samuel F. Berkovic, Gaetan Lesca, Karen L. Oliver   +17 more
wiley   +1 more source

Trisomy 21

Pediatrics in Review
Citation: 'trisomy 21' in the IUPAC Compendium of Chemical Terminology, 5th ed.; International Union of Pure and Applied Chemistry; 2025. Online version 5.0.0, 2025. 10.1351/goldbook.11325 • License: The IUPAC Gold Book is licensed under Creative Commons Attribution-ShareAlike CC BY-SA 4.0 International for individual terms.
openaire   +3 more sources

A Cross-sectional Study on Molecular Cartography: The Mapping of Down Syndrome with Cytogenetic Tools [PDF]

National Journal of Laboratory Medicine
Introduction: Down Syndrome (DS), or trisomy 21, is the most common genetic cause of intellectual disability among children, with an incidence of 1 in 700 births.
A Deepa, K Chandramouleeswari, M Dougul Regis   +2 more
doaj   +1 more source