Results 51 to 60 of about 5,018,310 (195)

The MacBrain Resource Center (MBRC) rhesus macaque postnatal brain histology datasets: Enabling new discoveries through NHP tissue and digital data Repositories

Journal of Anatomy, EarlyView.
The MacBrain Resource Center (MBRC) postnatal rhesus macaque brain histology datasets are organized into Collections that promote cost‐effective de novo research. This article provides examples from Collections 5, 6, and 7 and describes the histo‐ and immunohistochemical (IHC) processing of materials for Collection 6.
Valeria Mendoza‐Silva, Lucy Greene, Emma Burke, Cristina Canales, Julia Chocarro, Jose L. Lanciego, Khuleshwari Kurrey, Phil Barello, Aya Nusir, Nadine Kabbani, Kathleen S. Rockland, Dibyadeep Datta, Jon I. Arellano, Amy F. T. Arnsten, Yury M. Morozov, Bashir Ahmed, Zoltán Molnár, Caroline J. Zeiss, Pasko Rakic, Alvaro Duque   +19 more
wiley   +1 more source

Dualsteric and dual‐acting modulation of muscarinic receptors by antagonist KH‐5

British Journal of Pharmacology, Volume 183, Issue 19, Page 5769-5790, October 2026.
Abstract Background and purpose Muscarinic acetylcholine receptors are key therapeutic targets, and ligands engaging both orthosteric and allosteric sites may offer improved selectivity and efficacy. Here, we investigated whether the muscarinic antagonist KH‐5 acts as a dualsteric antagonist and defined its mode of interaction with muscarinic receptors.
Alena Janoušková‐Randáková, Eva Dolejší, Nikolai Chetverikov, Jan Jakubík   +3 more
wiley   +1 more source

Link between microstructure and tritiated water diffusivity in mortars

EPJ Web of Conferences, 2013
Ions and radionuclide diffusivity in concrete is one of the most important factors that determine service life and safety assessment of cement based structures in nuclear power plants and radioactive-waste repositories. Apart from the influence of cement
Dangla P., Le Bescop P., Dridi W., Larbi B., Petit L.   +4 more
doaj   +1 more source

Water‐Dispersible Ruthenium Nanocatalyst for Carbonyl Reduction With D2 or T2 in Aqueous Media

Angewandte Chemie, Volume 138, Issue 38, 14 September 2026.
We report the synthesis and characterization of water‐dispersible ruthenium nanoparticles that catalyze the reductive deuteration and tritiation of carbonyl compounds in aqueous media, enabling efficient access to a broad range of isotopically labeled polar molecules, including cyclic peptides, antibody‐drug conjugate linkers, pegylated derivatives ...
Elisa Martinelli, Rafael Jiménez Rioboo, Remo Weck, Sophie Feuillastre, Luis M. Martínez‐Prieto, Grégory Pieters, Volker Derdau   +6 more
wiley   +1 more source

Mathematical simulations for studying the effectiveness of HTO removal mechanism from spent fuel storage bay and estimating the environmental releases

Radiation Protection and Environment, 2019
The diffusion of tritiated water (HTO) vapor from the spent fuel storage bay to the spent fuel storage building (SFSB) may lead to internal exposure to occupational workers.
Lokesh Kumar, Rajendrakumar B Oza, Ranjit Sharma, Rayroath K Gopalakrishnan   +3 more
doaj   +1 more source

Quantum‐Level Influences on Enzyme Reactions and Their Ripple Effects on Biological Phenomena

Advanced Physics Research, Volume 5, Issue 9, September 2026.
Because living organisms are ultimately composed of atoms and molecules, quantum‐mechanical effects are expected to contribute to biological phenomena. Quantum biology seeks to elucidate life processes from a quantum‐mechanical perspective. This review discusses how quantum‐level effects, including quantum tunneling, may propagate from enzymatic proton‐
Takeshi Yasuda
wiley   +1 more source

DETRITIZATION OF AQUEOUS SOLUTIONS USING HIBSITE

Геохімія техногенезу, 2022
An important task in protecting the environment from tritium pollution is to find effective, simple, affordable, low-cost and low-energy methods for extracting tritium from large volumes of low- and intermediate-level aqueous solutions.
O. Pushkarov, I. Sevruk, Zubko O.V., Dolin V.V. (Jr.)   +3 more
doaj   +1 more source

Payload‐Based Clinical Pharmacology Review of Approved Antibody–Drug Conjugates: Commonalities and Considerations for Streamlined Development

Clinical Pharmacology &Therapeutics, Volume 120, Issue 3, Page 614-638, September 2026.
Antibody–drug conjugates (ADCs) combine the specificity of an antibody with the potency of a cytotoxic drug. Thirteen ADCs, utilizing seven unique cytotoxic payloads and targeting 11 distinct antigens, are currently approved by the US Food and Drug Administration as of June 2025, representing a rapidly growing and highly promising class of anticancer ...
Sijie Lu, Qingqing Xiao, Lixuan Qian, Siyuan Sun, Zhu Zhou, Michael Z. Liao, Chunze Li   +6 more
wiley   +1 more source

HICU PIE results of neutron-irradiated lithium metatitanate pebbles

Nuclear Materials and Energy
Lithium metatitanate (Li2TiO3) pebbles were irradiated with neutrons within the HICU (High neutron fluence Irradiation of pebble staCks for fUsion) experiment to investigate their material properties and tritium release behaviour in a post-irradiation ...
Julia Leys, Rolf Rolli, Hans-Christian Schneider, Regina Knitter   +3 more
doaj   +1 more source

On the Diffusion of Tritiated Water Through Skin

Journal of Investigative Dermatology, 1968
A recent paper in this journal by Downes et al (1) reported on the use of a simple in vitro method for determining the diffusion of water through skin by measuring the unidirectional flux of tritiated (radioactive water. The method consists in mounting a piece of skin as a barrier between two glass chambers and measuring the appearance of tritiated ...
openaire   +2 more sources