Results 101 to 110 of about 1,376 (263)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

On the cyclic homology theory of algebras

open access: yesScientific African
In this paper, the (Co)homology theory of pure algebra will be studied. We aim to study the homological theory of cyclic homology and its properties. The triviality property of cohomology groups of algebras will be obtained.
W.M. Mahmoud   +3 more
doaj   +1 more source

Next‐generation proteomics improves lung cancer risk prediction

open access: yesMolecular Oncology, EarlyView.
This is one of very few studies that used prediagnostic blood samples from participants of two large population‐based cohorts. We identified, evaluated, and validated an innovative protein marker model that outperformed an established risk prediction model and criteria employed by low‐dose computed tomography in lung cancer screening trials.
Megha Bhardwaj   +4 more
wiley   +1 more source

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

open access: yesMolecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak   +4 more
wiley   +1 more source

The Influence of Access Barriers on Outpatient Services Use among Low-income Households in Malaysia.

open access: yesAsia Pacific Journal of Health Management
Aim: Many people, particularly those from low-income and marginalised communities, face barriers when accessing healthcare services. Therefore, this study examined the influence of household characteristics and perceived access barriers on the ...
Aziz Jamal   +3 more
doaj   +1 more source

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

open access: yesMolecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad   +35 more
wiley   +1 more source

Mes ratés de terrain

open access: yesSociologies, 2017
I propose in this paper to return to the failures that have occurred during my life as a researcher in order to learn some lessons. I argue that, in human sciences, a failure in fieldwork is always better than no fieldwork at all.
Pierre Verdrager
doaj  

Triviality of outer derivations in lp(G) for one class of groups

open access: yesСовременная математика: Фундаментальные направления
In this paper, we study derivations in group rings completed by various types of norms. The main attention is paid to the class of groups in which conjugations act in a controlled manner in some sense.
A. A. Arutyunov, A. V. Naianzin
doaj   +1 more source

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