Results 91 to 100 of about 54,934 (280)
BDNF/TrkB signaling in stable coronary artery disease
Российский кардиологический журнал, 2023 Aim. To study the serum content of brain-derived neurotrophic factor (BDNF) and tyrosine kinase receptor B (TrkB) in patients with coronary artery disease (CAD) and evaluate the relationship of BDNF/TrkB signaling with the severity of coronary ...
O. V. Atamas +4 more
doaj +1 more source
Crosstalk Between Brain-Derived Neurotrophic Factor And N-Methyl-D-Aspartate Receptor Signaling In Neurons [PDF]
, 2008 Glutamate is the major excitatory neurotransmitter in brain exerting prosurvival effect on neurons via N-methyl-D-aspartate receptor (NMDAR) signaling under physiological conditions.
Georgiev, Danko +3 more
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The pharmacological perturbation of brain zinc impairs BDNF-related signaling and the cognitive performances of young mice. [PDF]
, 2018 Zinc (Zn2+) is a pleiotropic modulator of the neuronal and brain activity. The disruption of intraneuronal Zn2+ levels triggers neurotoxic processes and affects neuronal functioning.
Bomba, Manuela +13 more
core +3 more sources
Advanced Science, EarlyView.This research identified cardiac amyloid pathology, neurotrophic factor depletion, and reduced myocardial nerve function in a transgenic model of cerebral amyloidosis (Tg2576), Aβ‐challenged cardiomyocytes, and in human AD heart tissue. These findings carry significant diagnostic and therapeutic implications, emphasizing the role of neuro‐signaling ...
Andrea Elia +6 more
wiley +1 more source
The antidepressant hyperforin increases the phosphorylation of CREB and the expression of TrkB in a tissue-specific manner. [PDF]
, 2012 International audienceHyperforin is one of the main bioactive compounds that underlie the antidepressant actions of the medicinal plant Hypericum perforatum (St. John's wort).
Abrous, Djoher Nora +5 more
core +3 more sources
Advanced Science, EarlyView.This study presents a novel “in vivo–in vitro” therapeutic strategy for spinal cord injury by leveraging magnetically responsive piezoelectric nanomaterials. These nanomaterials enable targeted delivery of localized electrical stimulation at the injury site through noninvasive external magnetic actuation, thereby promoting axonal regeneration and ...
Zhihang Xiao +9 more
wiley +1 more source
Cancer Management and Research, 2020 Xiaoyan Hu,1 Wujun Zou,2 Dianzhong Liu,3 Gang Qin,2 Liang Jiang2 1Department of Pathogenic Biology, Southwest Medical University, Luzhou, Sichuan 646000, People’s Republic of China; 2Department of Otolaryngology Head and Neck Surgery, Affiliated ...
Hu X, Zou W, Liu D, Qin G, Jiang L
doaj
Specific effects of c-Jun NH2-terminal kinase-interacting protein 1 in neuronal axons
Neural Regeneration Research, 2016 c-Jun NH2-terminal kinase (JNK)-interacting protein 3 plays an important role in brain-derived neurotrophic factor/tropomyosin-related kinase B (TrkB) anterograde axonal transport.
Shu Tang +3 more
doaj +1 more source
Annals of Neurology, EarlyView.Objective Carpal tunnel syndrome (CTS) can drastically impair one's ability to work and interferes with activities of daily living. We recently demonstrated that, in rodents, conditioning electrical stimulation (CES) delivered to the nerve 7 days prior to surgery imparts a conditioning lesion‐like effect by accelerating the rate of regeneration along ...
Yusuke Osaki +19 more
wiley +1 more source
Enriched environment reduces glioma growth through immune and non-immune mechanisms in mice [PDF]
, 2015 Mice exposed to standard (SE) or enriched environment (EE) were transplanted with murine or human glioma cells and differences in tumour development were evaluated.
BENIGNI, GIORGIA +13 more
core +1 more source