Results 61 to 70 of about 54,934 (280)
TrkB signaling regulates the cold-shock protein RBM3-mediated neuroprotection
Life Science Alliance, 2021 The neuroprotective effects of the cold-shock protein RBM3 have broad appeal for therapy. RBM3 induction through cooling occurs through a non-canonical pattern of TrkB signaling.
Diego Peretti +7 more
semanticscholar +1 more source
BDNF–TrkB signaling and neuroprotection in schizophrenia [PDF]
Asian Journal of Psychiatry, 2013 Neurotrophins such as brain-derived neurotropic factor (BDNF), play critical role in neuronal survival, synaptic plasticity and cognitive functions. BDNF is known to mediate its action through various intracellular signaling pathways triggered by activation of tyrosine kinase receptor B (TrkB).
Chirayu D, Pandya +2 more
openaire +2 more sources
Biomolecular Concepts, 2019 Endometriosis is a common, often painful, condition that has significant implications for a woman’s fertility. Classically, endometriosis has been conceptualized as a local estrogen-mediated uterine condition driven by retrograde menstruation.
Anderson George
doaj +1 more source
Frontiers in Molecular Neuroscience, 2019 The signaling of brain-derived neurotrophic factor (BDNF) has been suggested to be impaired in Alzheimer’s disease (AD), which may compromise the function of BDNF upon neuronal activity and survival.
João Fonseca-Gomes +10 more
doaj +1 more source
Signalling mechanisms of long term facilitation of breathing with intermittent hypoxia. [PDF]
, 2013 Intermittent hypoxia causes long-term facilitation (LTF) of respiratory motor nerve activity and ventilation, which manifests as a persistent increase over the normoxic baseline for an hour or more after the acute hypoxic ventilatory response.
Pamenter, Matthew E, Powell, Frank L
core +1 more source
Adult trkB Signaling in Parvalbumin Interneurons is Essential to Prefrontal Network Dynamics
Journal of Neuroscience, 2021 Inhibitory interneurons expressing parvalbumin (PV) are central to cortical network dynamics, generation of γ oscillations, and cognition. Dysfunction of PV interneurons disrupts cortical information processing and cognitive behavior.
N. Guyon +11 more
semanticscholar +1 more source
Targeting TrkB–PSD-95 coupling to mitigate neurological disorders
Neural Regeneration ResearchTropomyosin receptor kinase B (TrkB) signaling plays a pivotal role in dendritic growth and dendritic spine formation to promote learning and memory.
Xin Yang +2 more
doaj +1 more source
Local BDNF Delivery to the Injured Cervical Spinal Cord using an Engineered Hydrogel Enhances Diaphragmatic Respiratory Function. [PDF]
, 2018 We developed an innovative biomaterial-based approach to repair the critical neural circuitry that controls diaphragm activation by locally delivering brain-derived neurotrophic factor (BDNF) to injured cervical spinal cord.
Ghosh, Biswarup +8 more
core +2 more sources
The gut-brain axis, BDNF, NMDA and CNS disorders [PDF]
, 2016 Gastro-intestinal (GI) microbiota and the ‘gut-brain axis’ are proving to be increasingly relevant to early brain development and the emergence of psychiatric disorders.
Maqsood, Raeesah, Stone, Trevor W.
core +1 more source
BDNF/TrkB activators in Parkinson's disease: A new therapeutic strategy
Journal of Cellular and Molecular MedicineParkinson's disease (PD) is a neurodegenerative disorder of the brain and is manifested by motor and non‐motor symptoms because of degenerative changes in dopaminergic neurons of the substantia nigra.
Naif H. Ali +8 more
semanticscholar +1 more source