Results 271 to 280 of about 317,876 (306)
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Current Opinion in Structural Biology, 1995
Detailed mechanisms for each step of the reaction catalyzed by both class I and class II aminoacyl-tRNA synthetases have been proposed on the basis of crystallographic data of aminoacyl-tRNA synthetases in complex with their different substrates. Despite the very different topologies of the two classes, there are striking and unanticipated chemical ...
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Detailed mechanisms for each step of the reaction catalyzed by both class I and class II aminoacyl-tRNA synthetases have been proposed on the basis of crystallographic data of aminoacyl-tRNA synthetases in complex with their different substrates. Despite the very different topologies of the two classes, there are striking and unanticipated chemical ...
openaire +3 more sources
Current Biology
Aminoacyl-tRNA synthetases hold the key to the genetic code and assign nucleic acid-based codons to amino acids, the building blocks of proteins. In their ability to recognize identity elements on transfer RNAs (tRNAs), some as simple as a single base pair, they ensure that the same proteins are formed each time information embedded in DNA is ...
Rasangi, Tennakoon, Haissi, Cui
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Aminoacyl-tRNA synthetases hold the key to the genetic code and assign nucleic acid-based codons to amino acids, the building blocks of proteins. In their ability to recognize identity elements on transfer RNAs (tRNAs), some as simple as a single base pair, they ensure that the same proteins are formed each time information embedded in DNA is ...
Rasangi, Tennakoon, Haissi, Cui
openaire +2 more sources
The expanding world of tRNA modifications and their disease relevance
Nature Reviews Molecular Cell Biology, 2021Tsutomu Suzuki
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tRNA therapeutics for genetic diseases
Nature Reviews Drug Discovery, 2023Jeff Coller, Zoya Ignatova
exaly
Design, construction, and functional characterization of a tRNA neochromosome in yeast
Cell, 2023Roy S K Walker +2 more
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tRNA dysregulation and disease
Nature Reviews Genetics, 2022Esteban A Orellana, Richard I Gregory
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ALKBH1-Mediated tRNA Demethylation Regulates Translation
Cell, 2016Fange Liu, Xiaoyun Wang, Ye Fu
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The emerging complexity of the tRNA world: mammalian tRNAs beyond protein synthesis
Nature Reviews Molecular Cell Biology, 2017Paul Schimmel
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