Uptake of Tropheryma whipplei by Intestinal Epithelia. [PDF]
Background: Tropheryma whipplei (TW) can cause different pathologies, e.g., Whipple’s disease and transient gastroenteritis. The mechanism by which the bacteria pass the intestinal epithelial barrier, and the mechanism of TW-induced gastroenteritis are currently unknown.
Friebel J +13 more
europepmc +3 more sources
A Case of Whipple's Disease Related Infectious Endocarditis
Whipple's disease is caused by Tropheryma whipplei and is known to have protean clinical presentation which could be influenced by patient's immunologic and genetic features.
N. V. Ivanova +4 more
doaj +1 more source
Tropheryma whipplei in Feces of Patients with Diarrhea in 3 Locations on Different Continents
We examined fecal specimens of patients with diarrhea from 3 continents for Tropheryma whipplei and enteropathogens. T. whipplei was most common in South Africa, followed by Singapore and Germany.
Gerhard E. Feurle +5 more
doaj +1 more source
Subcutaneous Nodules Caused by Tropheryma whipplei Infection
To help clarify the clinical manifestations, diagnosis, and treatment for Whipple disease, we report a case of a man in China infected with Tropheryma whipplei.
Lili Wang, Peng Su, Li Song, Lintao Sai
doaj +1 more source
Cultivation of \u3cem\u3eTropheryma whipplei\u3c/em\u3e from Cerebrospinal Fluid [PDF]
Whipple disease (WD) is a systemic disorder caused by the bacterium Tropheryma whipplei. Since the recognition of a bacterial etiology in 1961, many attempts have been made to cultivate this bacterium in vitro.
Fredricks, David N. +5 more
core +5 more sources
Tropheryma whipplei, the agent of Whipple's disease, inhibits phago-lysosome biogenesis to create a suitable niche for its survival and replication in macrophages. To understand the mechanism by which it subverts phagosome maturation, we used biochemical
Giovanna Mottola +6 more
doaj +1 more source
Tropheryma whipplei infection presenting as indolent endophthalmitis. [PDF]
Tropheryma whipplei (T. whipplei) infection can be difficult to diagnose due to its variable clinical manifestations and the limitations of standard diagnostic tests. This case describes a 78-year-old male with blurry vision and floaters in his right eye five months after cataract surgery, along with new onset weight loss and arthralgias ...
Waked R +5 more
europepmc +4 more sources
Service evaluation to establish the sensitivity, specificity and additional value of broad-range 16S rDNA PCR for the diagnosis of infective endocarditis from resected endocardial material in patients from eight UK and Ireland hospitals [PDF]
Infective endocarditis (IE) can be diagnosed in the clinical microbiology laboratory by culturing explanted heart valve material. We present a service evaluation that examines the sensitivity and specificity of a broad-range 16S rDNA polymerase chain ...
Alshafi, K +8 more
core +1 more source
Haemophilus influenzae and Moraxella catarrhalis were in highest abundance in non‐smoking severe asthma, neutrophilic inflammation and TAC2 phenotype of inflammasome activation compared to healthy subjects, while Haemophilus influenzae and Tropheryma whipplei in smoking/ex‐smoking severe asthma and TAC1 phenotype of TSLP and IL‐33 receptors and Type 2 ...
Ali Versi +113 more
wiley +1 more source
Constrictive pleuropericarditis: a dominant clinical manifestation in Whipple’s disease [PDF]
Background: Whipple’s disease is a rare, multisystemic, chronic infectious disease which classically presents as a wasting illness characterized by polyarthralgia, diarrhea, fever, and lymphadenopathy. Pleuropericardial involvement is a common pathologic
Alan N Baer +5 more
core +1 more source

