Acute Infections Caused by Tropheryma Whipplei [PDF]
Tropheryma whipplei is the causative bacterium of Whipple's disease. Its first culture has led to an enlargement of the field of the caused infections. Here, we comprehensively review acute T. whipplei infections. In a cohort study featuring 4000 children, T. whipplei was significantly more common in patients with diarrhea (4%) than in those without (1.
Lagier, Jean-Christophe +2 more
openaire +3 more sources
Rapidly progressive dementia and intractable diarrhea: a teaching case report and a systematic review of cognitive impairment in Whipple's disease [PDF]
Objective Whipple's disease (WD) is a systemic, chronic, relapsing disease caused by Tropheryma whipplei, which can mimic signs and symptoms of various clinical entities.
Lovati, Carlo +3 more
core +1 more source
ESCMID postgraduate technical workshop on intracellular bacteria: from biology to clinic. [PDF]
Infection by intracellular bacteria can lead to several diseases in both veterinary and human medicine. Unfortunately, the biology of these intracellular bacteria is highly complex due to their interactions with their host cells.
Greub, G., Pilloux, L.
core +2 more sources
False positive PCR detection of Tropheryma whipplei in the saliva of healthy people [PDF]
Background Tropheryma whipplei, the agent of Whipple's disease (WD), has been recently isolated and the genomes of two isolates have been fully sequenced.
Fenollar, Florence +2 more
core +3 more sources
The best treatment for Tropheryma whipplei infections is controversial. We report a patient who suffered from T. whipplei aortic native valve endocarditis that relapsed despite surgery and four weeks of intravenous ceftriaxone followed by several months ...
Stephane Emonet +8 more
doaj +1 more source
Phenotypic diversity of Tropheryma whipplei clinical isolates
Tropheryma whipplei is a bacterial pathogen responsible for a wide range of infections in humans, covering asymptomatic carriage, acute infections, chronic isolated infections and classic Whipple's disease. Although the bacterium is commonly found in the environment, it very rarely causes disease.
Boumaza, Asma Fatima +3 more
openaire +3 more sources
Mucosal immune response to Tropheryma whipplei
Whipple's disease is a rare infectious disease caused by the ubiquitously occurring Tropheryma whipplei in predisposed persons. Genetic or acquired defects in the mucosal and peripheral immune system become apparent as diminished Th1 immune functions with decreased production of IL-12 and IFN-gamma accompanied by an increased secretion of IL-4.
Sabine, Ring +2 more
openaire +2 more sources
Cerebrospinal Fluid Metabolome in Central Nervous System Infections: A Study of Diagnostic Accuracy
Objective To assess the diagnostic accuracy of metabolites in cerebrospinal fluid (CSF) for central nervous system (CNS) infections. Methods Patients were derived from three prospective cohort studies in the Netherlands. All studies included adults suspected of a CNS infection who underwent a diagnostic lumbar puncture.
Steven L. Staal +7 more
wiley +1 more source
Background Culture-negative endocarditis due to Tropheryma whipplei is a rare disease. Mostly the diagnosis is made by histologic examination of resected heart valve tissue.
Algin Ahmet +4 more
doaj +1 more source
Progressive dementia associated with ataxia or obesity in patients with Tropheryma whipplei encephalitis [PDF]
Background Tropheryma whipplei, the agent of Whipple's disease, causes localised infections in the absence of histological digestive involvement. Our objective is to describe T. whipplei encephalitis.
A Brown +68 more
core +7 more sources

