Results 201 to 210 of about 83,565 (267)

A Phase 1 Study of Convection‐Enhanced Delivery of Intraputaminal AAV2‐GDNF in Advanced Parkinson's Disease

Movement Disorders, EarlyView.
Abstract Background Parkinson's disease (PD) is a progressive neurodegenerative disorder. Neurotrophic therapeutic approaches have been limited in part by incomplete delivery to the putamen. We developed image‐guided convection‐enhanced delivery with real‐time monitoring to improve intraputaminal distribution of neurotrophic gene therapy. Objectives To
John D. Heiss, Debra J. Ehrlich, Codrin Lungu, Joseph Y. Choi, Gretchen Scott, Irene Dustin, Dima A. Hammoud, Peter Herscovitch, Russell R. Lonser, Kareem A. Zaghloul, Krystof Bankiewicz   +10 more
wiley   +1 more source

Analyses of eye lens stable isotopes across ontogeny of trophically diverse freshwater salmonids. [PDF]

PLoS One
Schumacher GT, Peebles EB, Furey NB, Kinnison MT, Kronisch GR, Murphy CA.   +5 more
europepmc   +1 more source

Ecosystem retrogression enhances cross‐domain microbial stability and increases the genetic potential for nutrient cycling

mLife, EarlyView.
Abstract Ecosystem retrogression drives nutrient depletion, reduced productivity, and profound reorganization of soil microbial communities. Using amplicon sequencing and genome‐resolved metagenomics, we examined how cross‐domain microbial networks and functional gene potential respond to long‐term phosphorus and nitrogen limitation along the well ...
Javier A. Ceja‐Navarro, Dishant Patel, Garret Genco, Alyssa Byer, Daliang Ning, Kenneth H. Wan, Susan E. Celniker, Jizhong Zhou, Paul Dijkstra, Bruce A. Hungate, Jennifer Pett‐Ridge, Eoin L. Brodie   +11 more
wiley   +1 more source

Ecological Stoichiometric Relationships Among Wood-Feeding Insects, Host Trees, and Soils in an Urban Tropical Ecosystem. [PDF]

Ecol Evol
Adedeji GA, Egubogo AC, Aiyeloja AA, Ojelade BS, David IO, Amaogu DC, Nelson ET.   +6 more
europepmc   +1 more source

Drivers of stability in plankton communities: dominance, asynchrony, and averaging effects across temporal, spatial and trophic scales

Oikos, EarlyView.
The origins of ecosystem stability have long intrigued ecologists. Recent theoretical advancements highlight three primary mechanisms driving stability: dominance, asynchrony and averaging. While plant community stability has been extensively studied, our understanding of marine community stability remains limited. Plankton, as key components of marine
Guido Occhipinti, Francesco Dattilo, Eva Álvarez, Cosimo Solidoro, Paolo Lazzari   +4 more
wiley   +1 more source

DNA metabarcoding to estimate diet overlap between the introduced Joro spider (Trichonephila clavata) and three native orb-weaving spiders. [PDF]

PLoS One
Grabarczyk EE, Schmidt JM.
europepmc   +1 more source

Genetic and Ecological Divergence Between Northwest Atlantic Killer Whale Populations. [PDF]

Ecol Evol
Kucheravy CE, de Greef E, Ferguson SH, Watt CA, Lawson JW, Kiszka JJ, Garroway CJ, Matthews CJD.   +7 more
europepmc   +1 more source

Diverging Food Web Functioning Around Southampton Island, Nunavut: The Influence of Primary Production Supply and Bathymetry. [PDF]

Ecol Evol
Amiraux R, Mundy CJ, Pierrejean M, Massicotte P, Ferguson SH, Fisk AT, Harris LN, Hedges KJ, Johnson KF, Niemi A, Rosenberg B, Ogloff WR, Watt CA, Yurkowski DJ.   +13 more
europepmc   +1 more source

Global Patterns of Mercury Speciation and Biomagnification in Sharks: Ecological Drivers and Food Safety Implications. [PDF]

Environ Sci Technol
Boldrocchi G, Spanu D, Ruiz López A, Garibaldi F, Lanteri L, Maggi A, Bettinetti R, Monticelli D.   +7 more
europepmc   +1 more source