Results 31 to 40 of about 5,459 (228)

Successful treatment of giant trophic ulcer of the lower leg of arterial genesis

Український журнал клінічної хірургії
Successful treatment of giant trophic ulcer of the lower leg of arterial ...
V. I. Lyakhovskyi, H. Y. Skrypnyk, O. M. Bezkorovainyi, A. L. Borkunov, A. V. Sydorenko, D. A. Shcherban   +5 more
doaj   +1 more source

Weizmannia coagulans XY2 Mitigates Copper Neurotoxicity via Gut–Brain Axis Modulation of Tryptophan Metabolism and Oxidative‐Inflammatory Crosstalk

iMetaOmics, EarlyView.
Copper interferes with tryptophan metabolism and 5‐HT levels by modulating intestinal flora. Intestinal barrier breakdown and inflammatory response trigger nerve damage under copper exposure. W. coagulans XY2 alleviates copper‐induced neurotoxicity by targeting a multi‐dimensional “tryptophan metabolism‐antioxidant defense‐gut‐brain axis” network.
Yufang Gao, Xiaodong Zheng, Fujie Yan
wiley   +1 more source

Aniridia‐associated keratopathy: Clinical and molecular mechanisms of disease progression and emerging therapeutic targets

Acta Ophthalmologica, EarlyView.
Abstract Congenital aniridia is a rare genetic disorder primarily caused by pathogenic variants of the PAX6 gene. It leads to various panocular anomalies, including aniridia‐associated keratopathy (AAK). This review highlights recent insights into its pathogenesis, focusing on clinical staging, microstructural changes in the cornea and molecular ...
N. Szentmáry, S. Suiwal, M. Amini, F. N. Fries, A. Náray, L. Latta, Z. Li, S. Li, S. Liu, S. L. Hsu, S. Kundu, G. Tóth, S. Trusen, J. Zimmermann, B. Seitz, B. Käsmann‐Kellner, Z. Hoxha, A. Langenbucher, O. Stachs, M. Cortón‐Perez, K. Tory, A. Csorba, Z. Z. Nagy, M. C. Acosta, J. Gallar, M. Csidey, E. Maka, T. Stachon   +27 more
wiley   +1 more source

Limb Revascularization in Patients with Diabetes Mellitus

RUDN Journal of Medicine, 2019
The review describes morbidity, mortality and possible complication rates for diabetic patients with peripheral arteries disease. The article demonstrates the modern tendency in the surgical treatment of peripheral arteries atherosclerosis, shows and ...
L. A. Bokeria, V. S. Arakelyan, V. G. Papitashvili, Sh. Sh. Tsurtsumiya   +3 more
doaj   +1 more source

Effects of Electroacupuncture at ST36 on Visceral Pain and Inflammatory Markers in IBS Rats

Neurogastroenterology &Motility, EarlyView.
Electroacupuncture (EA) at ST36 significantly reduced visceral pain and colonic inflammation in IBS model rats. EA increased pain thresholds, lowered AWR scores, and downregulated key inflammatory mediators (IL‐1β, IL‐6, TNF‐α, TRPV1, NF‐κB). These findings highlight ST36‐targeted EA as a promising therapeutic strategy for IBS visceral hypersensitivity
Ya‐bo Hao, Yan‐lin Liu, Xiao‐mei Wang, Kai Cheng, Qing‐yu Tu, Fei Dai, Xi‐bing Yang   +6 more
wiley   +1 more source

Microenvironment Modulation‐Based Nanomaterial‐Loaded Hydrogel Dressings for Diabetic Foot Ulcers: Research Progress and Future Perspectives

Advanced Materials Interfaces, Volume 13, Issue 5, 4 March 2026.
ABSTRACT Diabetic foot ulcer (DFU) is a chronic complication of diabetes, primarily caused by hyperglycemia, peripheral vascular disease, and neuropathy. Characterized by persistent hyperglycemia, impaired perfusion, inflammation, and infection, DFUs pose significant challenges to healing and are associated with high morbidity and amputation rates ...
Tang Yuqing, Chen Hong, Fan Weijing, Huang Renyan, You Yang, Liu Guobin   +5 more
wiley   +1 more source

Principles of the local treatment of venous trophic ulcers and the role of epidermal growth factor

Амбулаторная хирургия
Venous trophic ulcers affect approximately 1% of the working-age population of industrialized countries, which gives rise to massive direct and indirect healthcare expenditure.
V. Yu. Bogachev, O. A. Alukhanyan, V. N. Lobanov, A. R. Larina   +3 more
doaj   +1 more source

Obesity and Natural Products: Mechanisms, Therapeutic Potential, and Future Directions

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
Natural products such as EGCG, berberine, curcumin, and capsaicin modulate key metabolic pathways including AMPK activation, adipogenesis inhibition, and inflammatory signaling. While clinical trials demonstrate modest benefits on body weight and metabolic parameters, translational challenges related to bioavailability, dose feasibility, and regulatory
Ohoud M. Marie, Abdelghafar Abu‐Elsaoud   +1 more
wiley   +1 more source

USE OF MILIACYLЕ AND PHYSICAL METHODS IN THE TREATMENT OF TROPHIC ULCERS OF LOWER LIMBS

Креативная хирургия и онкология, 2017
The clinical studies included 340 patients with trophic ulcers in lower limbs. It is for the first time that the therapeutic efficacy of local application of Miliacyle combined with magnetolasertherapy has been studied in 124 patients with trophic ulcers
B. G. Nuzov, A. A. Stadnikov, O. B. Nuzova   +2 more
doaj   +1 more source

Cell and Gene Therapy in Equine Ocular Disease

Veterinary Ophthalmology, Volume 29, Issue 2, March 2026.
ABSTRACT Equine ocular disease is common and often challenging to treat using traditional methods. This has led to the development of new therapies. Like human medicine, veterinary medicine is adopting cellular and gene therapy as innovative approaches. Equine ocular disease is a particularly promising area for these techniques.
Kimberly A. S. Young, Lauren V. Schnabel, Brian C. Gilger   +2 more
wiley   +1 more source