Results 71 to 80 of about 191,401 (250)

Mycolactone Diffuses into the Peripheral Blood of Buruli Ulcer Patients - Implications for Diagnosis and Disease Monitoring. [PDF]

open access: yes, 2011
BACKGROUND: Mycobacterium ulcerans, the causative agent of Buruli ulcer (BU), is unique among human pathogens in its capacity to produce a polyketide-derived macrolide called mycolactone, making this molecule an attractive candidate target for diagnosis ...
Le Chevalier, Fabien   +53 more
core   +2 more sources

Pharmacotherapeutic efficacy of gel Kvotlan in the treatment of trophic ulcers of venous ethiology

open access: yesActa Biomedica Scientifica, 2015
Authors of given article conducted an estimation of pharmacotherapeutic efficiency of gel Kvotlan in the treatment of long-to-heal trophic ulcers of venous ethiology.
A. N. Plekhanov, O. A. Shabatina
doaj  

Multifunctional Hydrogels: Rational Design and Application in Regenerative Medicine

open access: yesMedComm, Volume 7, Issue 10, October 2026.
Multifunctional hydrogels represent a paradigm shift in regenerative medicine, integrating rational material design with bioactive functionality to address complex tissue repair challenges. This review systematically examines the molecular engineering, structure–function relationships, and translational landscape of advanced hydrogel systems, spanning ...
Linyang Song   +4 more
wiley   +1 more source

Hair Follicle‐Derived Grafting for Chronic Cutaneous Wounds: A Systematic Review of Clinical Outcomes

open access: yesInternational Wound Journal, Volume 23, Issue 10, October 2026.
ABSTRACT To evaluate clinical outcomes of autologous follicular unit and scalp‐derived grafting techniques in the treatment of chronic cutaneous wounds. A systematic review was conducted in accordance with PRISMA guidelines. PubMed/MEDLINE and Embase were searched through February 2026.
Mara Hartoyo   +2 more
wiley   +1 more source

Experience in the use of wound-healing collagen dressings in the complex treatment of venous trophic ulcers

open access: yesЛечащий Врач
Background. Venous trophic ulcers are a typical manifestation of decompensation of chronic venous insufficiency of the lower extremities. The causes of venous trophic ulcers are chronic vein diseases such as varicose veins of the lower limbs, pelvis ...
A. V. Teplikov, A. I. Cherepanin
doaj   +1 more source

Chronic Limb‐Threatening Ischemia Shows No Adaptability of Mitochondrial Function After Revascularisation

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 20, October 2026.
ABSTRACT Peripheral arterial disease (PAD) impairs limb perfusion, leading to myopathy characterised by altered mitochondrial content and respiration. Because ischemic muscle appears to adapt differently across PAD stages, we examined stage‐specific skeletal‐muscle mitochondrial function before and after successful revascularisation. Muscle biopsies of
Fiona Speichinger   +8 more
wiley   +1 more source

Venous trophic ulcer treatment

open access: yes, 2011
У роботі представлено результати хірургічного лікування 107 хворих з хронічною венозною недостатністю (С6) в стадії декомпенсації. Усі хворі на етапі доопераційної корекції венозного кровоплину лікувались консервативно із застосуванням компресійної пов’
Русин, Василь Іванович   +3 more
core  

Cellularized Skin Substitute Bioengineering for Regenerative Medicine: Cell Sources, Culture Strategies, and Transition Toward Defined, Xeno‐Free Culture Systems

open access: yesAdvanced Healthcare Materials, Volume 15, Issue 34, 11 September 2026.
Advances in cell sources, bioengineering, and manufacturing are reshaping the design of skin substitutes. This review highlights emerging strategies driving skin tissue engineering and discusses their potential to enable safer, reproducible, and clinically accessible skin substitutes for regenerative medicine.
Gilles Lemaître   +7 more
wiley   +1 more source

A Plant Photoregulator‐Inspired S‐Type Heterojunction System for Diabetic Keratopathy via Tri‐Modal Light‐Driven Immunometabolic Reprogramming, Tissue Repair, and Antibacterial Activity

open access: yesAdvanced Science, Volume 13, Issue 53, 24 September 2026.
To address the multifaceted imbalance in diabetic keratopathy, a light‐responsive biomimetic platform (WCNx‐Rh2) is developed and integrates glucose degradation, immune modulation, and antibacterial defense through a designed heterojunction and screened immunomodulator. WCNx‐Rh2 reduces AGEs/ROS and inflammatory signaling, reprogramming dendritic cells
Mengzhen Zhao   +8 more
wiley   +1 more source

Bone Marrow Mesenchymal Stem Cells Rescue Tendon Injury by Regulating FTO‐Mediated m6A Methylation of ELOB

open access: yesJournal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Bone marrow mesenchymal stem cells (BMSCs) promote tendon injury repair by enhancing tenocyte function and regulating the FTO/m6A/ELOB axis. Mechanistically, BMSCs lead to the upregulation of FTO and m6A modification, which subsequently suppresses ELOB expression.
Zhao‐Rong Dai   +2 more
wiley   +1 more source

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