Results 41 to 50 of about 4,857 (180)
Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang +3 more
wiley +1 more source
ABSTRACT Although infantile hemangiomas (IH) are common vascular tumors of childhood, associated nail abnormalities are rare. We report a child with a large segmental IH of the upper limb with marked, ipsilateral nail clubbing, which gradually improved until the age of 7 years.
Stefan Blunder +5 more
wiley +1 more source
Understanding extracellular vesicles in antiaging
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad +3 more
wiley +1 more source
ABSTRACT Objectives Hansen disease is a neglected infectious disease associated with reactional inflammation, neuropathy and long‐term disability. Renal involvement and sarcopenia have been described separately, but their clinical coexistence has received limited attention. This review examines evidence for a hypothesised renal–functional vulnerability
Kleberson de Oliveira +6 more
wiley +1 more source
ABSTRACT Surgical wound complications remain a major challenge, particularly in high‐risk patients. Closed‐incision negative pressure wound therapy (ciNPWT) and adhesive mesh closure systems have shown benefits independently, but their combined use has not been previously evaluated.
Pablo Sanz‐Ruiz +5 more
wiley +1 more source
ABSTRACT Objective Trigeminal trophic syndrome (TTS) is a rare condition caused by trigeminal nerve injury, classically characterized by anaesthesia, paresthesia and facial ulceration. We present two cases of TTS successfully managed with regional nerve blocks and onabotulinumtoxinA. Methods Two patients—a 54‐year‐old woman and a 65‐year‐old man—with a
Shamin Masrour, Rhea Sudhakaran
wiley +1 more source
If the patient is depressed or gives way to fear, he must be encouraged , not with false hopes but by pointing to other cases who have made satisfactory improvement. The kind-hearted sentimentalist who pities the leper as a hopeless incurable, who paneers to his besetting sins of depression and dejection, who gives charity in such a way as to dog up ...
openaire +1 more source
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun +7 more
wiley +1 more source
MODERN VIEW ON TREATMENT OF TROPHIC ULCERS
Article is devoted to one of ancient sections of medicine treatment of wounds. However treatment is long not healing wounds and now remains to one of important problems of medicine. Terms of healing of ulcers at the majority of patients make
I. L. Mikitin +4 more
doaj +1 more source
EBND alone upregulates neurofilament expression but does not induce neurite outgrowth in PC12 cells. With suboptimal NGF, EBND synergistically promotes neuronal differentiation via the TrkA‐ERK1/2‐CREB‐BDNF pathway. This effect is blocked by the TrkA inhibitor GW441756, confirming a TrkA‐dependent mechanism.
Wen Zhang +9 more
wiley +1 more source

