Results 41 to 50 of about 4,857 (180)

Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence

open access: yesJournal of Periodontal Research, EarlyView.
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang   +3 more
wiley   +1 more source

Nail Clubbing‐Associated With a Large Segmental Infantile Hemangioma of the Arm in a Patient With PHACES Syndrome

open access: yesPediatric Dermatology, EarlyView.
ABSTRACT Although infantile hemangiomas (IH) are common vascular tumors of childhood, associated nail abnormalities are rare. We report a child with a large segmental IH of the upper limb with marked, ipsilateral nail clubbing, which gradually improved until the age of 7 years.
Stefan Blunder   +5 more
wiley   +1 more source

Understanding extracellular vesicles in antiaging

open access: yesPeriodontology 2000, EarlyView.
Abstract Background Aging is a multifactorial process marked by gradual cellular dysregulation, regulated by hallmarks, including genomic instability, mitochondrial dysregulation, and chronic inflammation. Extracellular vesicles (EVs), especially exosomes, have emerged as pivotal mediators of cell‐to‐cell communication with potential roles in both ...
Paras Ahmad   +3 more
wiley   +1 more source

Renal and Functional Vulnerability in Hansen Disease: A Framework for Chronic Infectious Disability in Endemic Settings

open access: yesTropical Medicine &International Health, EarlyView.
ABSTRACT Objectives Hansen disease is a neglected infectious disease associated with reactional inflammation, neuropathy and long‐term disability. Renal involvement and sarcopenia have been described separately, but their clinical coexistence has received limited attention. This review examines evidence for a hypothesised renal–functional vulnerability
Kleberson de Oliveira   +6 more
wiley   +1 more source

Combined Use of Adhesive Mesh Closure and Closed‐Incision Negative Pressure Therapy for High‐Risk Surgical Wounds: A Proof‐Of‐Concept Study

open access: yesInternational Wound Journal, Volume 23, Issue 11, November 2026.
ABSTRACT Surgical wound complications remain a major challenge, particularly in high‐risk patients. Closed‐incision negative pressure wound therapy (ciNPWT) and adhesive mesh closure systems have shown benefits independently, but their combined use has not been previously evaluated.
Pablo Sanz‐Ruiz   +5 more
wiley   +1 more source

Regional Nerve Blocks and OnabotulinumtoxinA in the Management of Trigeminal Trophic Syndrome: A Case Report of a Novel Multimodal Approach

open access: yesOral Surgery, Volume 19, Issue 4, Page 370-372, November 2026.
ABSTRACT Objective Trigeminal trophic syndrome (TTS) is a rare condition caused by trigeminal nerve injury, classically characterized by anaesthesia, paresthesia and facial ulceration. We present two cases of TTS successfully managed with regional nerve blocks and onabotulinumtoxinA. Methods Two patients—a 54‐year‐old woman and a 65‐year‐old man—with a
Shamin Masrour, Rhea Sudhakaran
wiley   +1 more source

TREATMENT OF TROPHIC ULCERS

open access: yesLeprosy Review, 1939
If the patient is depressed or gives way to fear, he must be encouraged , not with false hopes but by pointing to other cases who have made satisfactory improvement. The kind-hearted sentimentalist who pities the leper as a hopeless incurable, who paneers to his besetting sins of depression and dejection, who gives charity in such a way as to dog up ...
openaire   +1 more source

Programming Gut Microbiome Function Through Cross‐Feeding: From Ecological Mechanisms to Live Biotherapeutics

open access: yesAdvanced Science, Volume 13, Issue 55, 5 October 2026.
This graphical abstract presents gut microbial cross‐feeding through a Mechanism–Technology–Application framework. It summarizes major resource‐transfer modes, the experimental and computational tools used to establish causality, and potential interventions involving dietary substrates, live biotherapeutic products, and engineered microbes.
Chuankai Sun   +7 more
wiley   +1 more source

MODERN VIEW ON TREATMENT OF TROPHIC ULCERS

open access: yesКреативная хирургия и онкология, 2017
Article is devoted to one of ancient sections of medicine treatment of wounds. However treatment is long not  healing  wounds and  now remains  to one of important problems of medicine.  Terms of  healing  of  ulcers at  the  majority  of  patients make 
I. L. Mikitin   +4 more
doaj   +1 more source

Enzyme‐Digested Edible Bird's Nest Promotes NGF‐Induced Differentiation of PC12 Cells by Activating the TrkA‐ERK1/2‐CREB‐BDNF Signaling Pathway

open access: yesFood Science &Nutrition, Volume 14, Issue 10, October 2026.
EBND alone upregulates neurofilament expression but does not induce neurite outgrowth in PC12 cells. With suboptimal NGF, EBND synergistically promotes neuronal differentiation via the TrkA‐ERK1/2‐CREB‐BDNF pathway. This effect is blocked by the TrkA inhibitor GW441756, confirming a TrkA‐dependent mechanism.
Wen Zhang   +9 more
wiley   +1 more source

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