Results 1 to 10 of about 92,904 (199)

Hypothesis on the possible relevance of the immunogenic cell death in the treatment of gestational trophoblastic neoplasms [PDF]

Translational Oncology, 2021
The genetic background and the antigenic landscape of cancer cells play a critical role in the response to immunotherapies. A high tumor antigenicity, together with an increased adjuvanticity potentially induced by a peculiar type of cell death, namely ...
G. Frega, O. Kepp, D. Turchetti, A. Rizzo, M.A. Pantaleo, G. Brandi   +5 more
doaj   +2 more sources

Machine learning-driven survival prediction in gestational trophoblastic neoplasms: a focus on PSTT and ETT prognosis [PDF]

Frontiers in Oncology
IntroductionThe clinicopathological characteristics and prognosis of placental site trophoblastic tumor (PSTT) and epithelioid trophoblastic tumor (ETT) have not been well summarized.
Sakhr Alshwayyat, Zena Haddadin, Mustafa Alshwayyat, Tala Abdulsalam Alshwayyat, Ramez M. Odat, Mohammed Al-mahdi Al-kurdi, Saoussane Kharmoum   +6 more
doaj   +2 more sources

A case report: false hCG trail: dysgerminoma imitates gestational trophoblastic disease [PDF]

AJOG Global Reports
Ovarian malignant germ cell tumors (MOGCTs) represent approximately 5% of all ovarian malignancies. However, in women aged 10 to 30, they account for up to 70% of ovarian neoplasms and may occasionally occur bilaterally.
Anna Babkova, PhD, Helena Robova, PhD, Hana Malikova, PhD, Jana Drozenova, MD, Borek Sehnal, PhD, Nikola Janovska, MD, Michael J. Halaska, PhD, Lukas Rob, PhD   +7 more
doaj   +2 more sources

Laparoscopic hysterectomy as a treatment modality for gestational trophoblastic neoplasia: A report of two cases [PDF]

Vojnosanitetski Pregled, 2022
Introduction. Measuring the serum levels of human chorionic gonadotropin beta isoform (β-hCG) remains a crucial marker for diagnosing gestational trophoblastic neoplasms (GTNs). Choriocarcinoma is commonly diagnosed due to extremely high levels of β-hCG,
Jokanović Predrag, Rakić Aleksandar
doaj   +1 more source

Gestational trophoblastic disease in Switzerland: retrospective study of the impact of a regional reference centre

Swiss Medical Weekly, 2021
AIMS OF THE STUDY The European Society of Medical Oncology (ESMO) recommends that countries should have reference centres to provide adequate diagnosis and treatment of gestational trophoblastic disease.
Aurore Fehlmann, Khadidja Benkortbi, Ginette Rosseel, Ulrike Meyer-Hamme, Jean-Christophe Tille, Frédérique Sloan-Béna, Ariane Paolini-Giacobino, Anne-Laure Rougemont, Alexandre Bodmer, Diomidis Botsikas, Patrice Mathevet, Patrick Petignat, Manuela Undurraga Malinverno   +12 more
doaj   +1 more source

Is There a Role for Surgery in the Management of Gestational Trophoblastic Neoplasia? [PDF]

Middle East Journal of Cancer, 2022
Background: Gestational trophoblastic diseases are treated with chemotherapy, but some patients are resistant to it and require surgeries. The role of surgery in the management of these patients is not clearly defined.
Malihe Hasanzadeh, Fatemeh Homaee Shandiz, Nooshin Izadpanahee, Mansoureh Mottaghi   +3 more
doaj   +1 more source

Case report: Using DNA short tandem repeats to confirm nongestational origin of pulmonary choriocarcinoma

Frontiers in Oncology, 2022
Gestational trophoblastic neoplasias (GTN) are malignant neoplasms that occur in pregnant or recently pregnant women. Choriocarcinoma (CCA) is a highly aggressive and rare GTN, and cases outside the female genital tract are commonly seen as secondary ...
Filipa Ferreira da Silva, Rita Barata, Inês Rolim, Catarina Carvalheiro, Nuno Gil, Marcos Pantarotto   +5 more
doaj   +1 more source

Epithelioid Trophoblastic Tumour: A Case with Genetic Linkage to a Child Born over Seventeen Years Prior, Successfully Treated with Surgery and Pembrolizumab

Current Oncology, 2021
Epithelioid trophoblastic tumours are rare neoplasms showing differentiation towards the chorion leave-type intermediate cytotrophoblast, with only a handful of cases being reported in the literature.
David Pisani, Jean Calleja-Agius, Riccardo Di Fiore, John J. O’Leary, James P. Beirne, Sharon A. O’Toole, Ana Felix, Ian Said-Huntingford   +7 more
doaj   +1 more source

Epithelioid trophoblastic tumor coexisting with choriocarcinoma around an abdominal wall cesarean scar: a case report and review of the literature

Journal of Medical Case Reports, 2020
Background Mixed gestational trophoblastic neoplasms are extremely rare and comprise a group of fetal trophoblastic tumors including choriocarcinomas, epithelioid trophoblastic tumors, and placental site trophoblastic tumors.
Chunfeng Yang, Jianqi Li, Yuanyuan Zhang, Hanzhen Xiong, Xiujie Sheng   +4 more
doaj   +1 more source

Therapeutic approach to the iatrogenic invasive mole: A report of two cases [PDF]

Vojnosanitetski Pregled, 2022
Introduction. Invasive mole, a form of gestational trophoblastic neoplasia (GTN), is defined as penetration of molar tissue into the myometrium and/or presence of extra-uterine metastases.
Rakić Aleksandar, Nikolić Branka, Radojičić Ognjen, Džuverović Marko   +3 more
doaj   +1 more source