Results 81 to 90 of about 6,910 (194)

The Therapeutic Potential of Stem Cell Therapy for Doxorubicin‐Induced Cardiotoxicity: A Narrative Review

Health Science Reports, Volume 9, Issue 8, August 2026.
ABSTRACT Background and Aims Doxorubicin (DOX) is a potent anthracycline chemotherapeutic agent whose clinical utility is significantly constrained by severe side effects, most notably DOX‐induced cardiotoxicity (DIC). Pathophysiological mechanisms of DIC include oxidative stress, mitochondrial dysfunction, programmed cell death, and inflammation ...
Ali Mirzaei, Pouria Rezaei, Reza Golchin Vafa, Saleheh Jahani, Reza Arefnezhad, Hossein Fatemian, Mohammad Hossein Nikoo, Amirhossein Sahebkar, Fatemeh Rezaei‐Tazangi   +8 more
wiley   +1 more source

Review of potential doppler ultrasonographic findings in patients with confirmed gestational trophoblastic neoplasms [PDF]

Vojnosanitetski Pregled, 2006
Nikolić Branka, Lazić Jelena
doaj   +1 more source

SIRT Family: Biological Functions and Therapeutic Targets

MedComm, Volume 7, Issue 8, August 2026.
SIRT1–SIRT7 networks from transgenic mice to human‑relevant therapeutic targets. SIRT1–SIRT7 form an isoform‑, organ‑, and disease‑specific regulatory network. Transgenic Sirt1–7 mouse models define central regulatory SIRTs (SIRT1, SIRT3, SIRT6), context‑dependent modifiers (SIRT2, SIRT4, SIRT5, SIRT7), and their key mechanisms and target organs. These
Jia‐Yi Wang, Feng‐Li Jiang, Fang‐Yuan Zhang, Dong‐Hui Huang, Xiao‐Ying Li, Song Gao, Hua You, Qi‐Jun Wu, Huan‐Huan Chen, Ting‐Ting Gong   +9 more
wiley   +1 more source

Glucose Transporter 1 in Health and Disease

MedComm, Volume 7, Issue 8, August 2026.
As the quintessential facilitator of basal glucose uptake, glucose transporter 1 (GLUT1) is indispensable for maintaining systemic energy homeostasis. This graphical abstract delineates the multidimensional landscape of GLUT1 in normal physiology. It highlights its tissue‐specific metabolic roles—from fueling erythrocytes and fetal development to ...
Yi Tai, Zhihao Chen, Yuping Zhu, Weidong Han   +3 more
wiley   +1 more source

Embryonic Mediators of Embryo–Uterus Communication, Implantation and Pregnancy

Molecular Reproduction and Development, Volume 93, Issue 8, August 2026.
ABSTRACT Successful reproduction in eutherian mammals requires intimate connections between the embryo and uterus, involving adhesion, attachment and placentation, with or without invasion of the endometrium. The complex dialogue between embryo and uterus involves numerous molecules and pathways.
Keith E. Latham
wiley   +1 more source

Immunophenotypic assessment of pure embryonal carcinoma and yolk sac tumour suggests that reprogramming to non‐seminoma occurs outside the spermatogonial niche

Histopathology, Volume 89, Issue 2, Page 303-311, August 2026.
Immunohistochemical analysis of transcription factors in GCNIS associated with pure EC and YST suggests that reprogramming to non‐seminoma occurs outside the spermatogonial niche. In these tumors, reprogramming may occur immediately upon invasion of the stroma or within seminiferous tubules but outside the spermatogonial niche (i.e., in intratubular ...
Daisy Maharjan, Květoslava Michalová, Joao Lobo, Jennifer Gordetsky, Fiona MacLean, Ankur R Sangoi, Daniel Berney, Chia‐Sui Kao, Costantino Ricci, Adeboye O Osunkoya, Maria Rosaria Raspollini, Geert JLH van Leenders, Muhammad T Idrees, Lee Ann Baldridge, Thomas M Ulbright, Andres M Acosta   +15 more
wiley   +1 more source

The clinicopathological features of intermediate trophoblastic tumor in the pineal region

Chinese Journal of Contemporary Neurology and Neurosurgery, 2012
Objective To evaluate the clinicopathological features of intermediate trophoblastic tumor (ITT) in the pineal region. Methods A retrospective study was performed to analyse the diagnostic and therapeutic process of 1 case with ITT in the pineal region ...
Yun⁃xiang ZHANG, Ding⁃rong ZHONG, Ming⁃ming HU, Tao YUAN, Gui⁃lin LI   +4 more
doaj  

Marked attenuation of P63 expression in plasmacytoid urothelial carcinoma with expanded immunohistochemical framework including E‐cadherin, P120, HER2 and TRPS1

Histopathology, Volume 89, Issue 2, Page 338-346, August 2026.
Plasmacytoid urothelial carcinoma demonstrates marked attenuation of p63 expression together with frequent disruption of the E‐cadherin–p120 adhesion complex, supporting its characteristic discohesive growth pattern. Standardized HER2 scoring identifies a substantial positive subset, highlighting diagnostic pitfalls and potential therapeutic relevance ...
Busra Yaprak Bayrak, Kemal Kosemehmetoglu, Busra Ozbek, Sercan Simsek, Murat Oktay, Ganime Coban, Dilara Irem Arslan Kahraman, Egemen Akıncıoglu, Melek Buyukgok, Selin Colak, Hatice Nese Dogan, Burak Gurel, Selva Kabul, Kerem Karaca, Elif Ozsagir, Ece Ozturk, Havva Serap Toru, Gupse Turan, Nazif Alperen Yıldırım, Ozlem Nur Yıldız, Yasemin Yuyucu Karabulut, Liang Cheng, Mahmut Akgul   +22 more
wiley   +1 more source

Elevation of hCG in CSF in pinealoblastoma: a pitfall rescued by pathological examination

Acta Neuropathologica Communications
Human chorionic gonadotropin (hCG) is a hormone that may be abnormally secreted in several tumour types, including intracranial germ cell tumours. In pineal region tumors, hCG is a key tumor marker.
François Bouille, Karima Mokhtari, Bertrand Mathon, Jérôme Alexandre Denis, Lucia Nichelli, Ahmed Idbaih, François Doz, Alice Laurenge   +7 more
doaj   +1 more source

Whole genome uniparental isodisomy detected using single nucleotide polymorphism (SNP) microarray in molar pregnancy: a case report

Molecular Cytogenetics
Background Gestational trophoblastic neoplasms consist of complete and partial hydatidiform moles, both of which are considered aberrant conceptuses.
Onyinye O. Okonkwo, Veronica Ortega, Sheila Kane, Galina Aldrete, Paulina Ramirez, Philip T. Valente, Gopalrao V.N. Velagaleti   +6 more
doaj   +1 more source