Results 151 to 160 of about 87,103 (196)
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Intermediate Trophoblast in Germ Cell Neoplasms
The American Journal of Surgical Pathology, 1987One-hundred-twenty-four germ cell tumors and 11 gestational choriocarcinomas were assessed immunohistochemically for the presence of the following placental markers: human chorionic gonadotrophin, human placental lactogen, and pregnancy-specific beta-1 glycoprotein, and for the expression of cytokeratin.
J C, Manivel +3 more
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Genetic origin of malignant trophoblastic neoplasms
Cancer Genetics and Cytogenetics, 1994The genetic origin of three trophoblastic neoplasms (two choriocarcinomas and a placental site trophoblast tumor (PSTT)] was determined by analysis of the restriction fragment length polymorphism (RFLP) pattern. One choriocarcinoma, which was believed not illogically to have developed from an antecedent complete mole, contained both paternal and ...
T, Arima +4 more
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Metastatic Adnexal Trophoblastic Neoplasm
Journal of Computer Assisted Tomography, 1988We report a case of pathologically proven metastatic trophoblastic neoplasm involving the adnexa which occurred after dilatation and curettage and chemotherapy. Duplex doppler ultrasound demonstrated increased vascularity in the adnexa. Angiography was sensitive but did not decisively distinguish between tumor in the adnexa and arteriovenous fistula in
D R, Mirich +4 more
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Worldwide Controversies in Gestational Trophoblastic Neoplasms
International Journal of Gynecology & Obstetrics, 1977ABSTRACTThis article reviews worldwide controversies concerning gestational trophoblastic neoplasms (hydatidiform mole, invasive mole, and choriocarcinoma). The epidemiology, endocrinology, histopathologic grading, classification, diagnosis, treatment, management and follow‐up (including chemotherapy, irradiation, and immunotherapy) of gestational ...
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Gestational trophoblastic neoplasms: Morphologic considerations
Human Pathology, 1977Abnormal trophoblastic proliferation is the hallmark of a spectrum of lesions constituting the gestational trophoblastic neoplasms. Rapid proliferation, infiltration, vascular invasion, hematogenous dissemination, and spontaneous regression are features of both normal and neoplastic trophoblast.
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Primary chemotherapy for nonmetastatic gestational trophoblastic neoplasms
American Journal of Obstetrics and Gynecology, 1967Abstract This report summarizes our 7 years' experience in the methotrexate chemotherapy of 58 patients with nonmetastatic gestational trophoblastic neoplasms. Of these patients, 54 (93 per cent) entered sustained complete remission. Three of the remaining 4 patients with methotrexate-resistant disease later entered remission with either hysterectomy
C B, Hammond +4 more
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Malignant trophoblastic neoplasms with different modes of origin
Cancer Genetics and Cytogenetics, 1995The genetic origin of 24 trophoblastic neoplasms was determined using PCR polymorphisms. Based on pregnancy history, these tumors included nine postmolar trophoblastic tumors, 12 tumors preceded by live birth or abortion, and three nongestational tumors.
T, Arima +7 more
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The Role of Methotrexate in the Chemotherapy of Gestational Trophoblastic Neoplasms
1984The successful use of methotrexate in metastatic choriocarcinoma in 1956 (1) marked a milestone in the history of curative cancer chemotherapy. The survival of patients with widespread disease increased from 10% in the pre-chemotherapy era (2) to 47% in 1961 (3), 74% in 1965 (4), and to about 90% at the present time (5–7).
A, Sobrero, J R, Bertino
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Gestational Trophoblastic Neoplasms: The Role of Chemotherapy and Surgery
Surgical Clinics of North America, 1978Current methods of diagnosis and treatment are reviewed. Special attention is directed to the diagnostic and therapeutic problems associated with the presence of brain metastases.
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