Results 191 to 200 of about 8,177 (250)
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Gestational Trophoblastic Neoplasms
Journal of Obstetric, Gynecologic & Neonatal Nursing, 1986Gestational trophoblastic neoplasms have evolved from one of the most rapidly fatal malignancies to potentially one of the most curable, but these diseases have devastating emotional effects on the victims. Etiology, epidemiology, pathophysiology, diagnosis, and medical treatment are reviewed.
S M, Celeste, M D, Smith
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PREGNANCIES AFTER CHEMOTHERAPY OF TROPHOBLASTIC NEOPLASMS
Obstetrical & Gynecological Survey, 1970We have analyzed 88 pregnancies in 50 women who had previously been treated for gestational trophoblastic neoplasms with chemotherapeutic agents. No increase in fetal wastage, congenital abnormalities or complicated pregnancies was noted, suggesting that these drugs do not damage human oocytes in the doses and time periods used.
D H, Van Thiel, G T, Ross, M B, Lipsett
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Metastatic Adnexal Trophoblastic Neoplasm
Journal of Computer Assisted Tomography, 1988We report a case of pathologically proven metastatic trophoblastic neoplasm involving the adnexa which occurred after dilatation and curettage and chemotherapy. Duplex doppler ultrasound demonstrated increased vascularity in the adnexa. Angiography was sensitive but did not decisively distinguish between tumor in the adnexa and arteriovenous fistula in
D R, Mirich +4 more
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Genetic origin of malignant trophoblastic neoplasms
Cancer Genetics and Cytogenetics, 1994The genetic origin of three trophoblastic neoplasms (two choriocarcinomas and a placental site trophoblast tumor (PSTT)] was determined by analysis of the restriction fragment length polymorphism (RFLP) pattern. One choriocarcinoma, which was believed not illogically to have developed from an antecedent complete mole, contained both paternal and ...
T, Arima +4 more
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Intermediate Trophoblast in Germ Cell Neoplasms
The American Journal of Surgical Pathology, 1987One-hundred-twenty-four germ cell tumors and 11 gestational choriocarcinomas were assessed immunohistochemically for the presence of the following placental markers: human chorionic gonadotrophin, human placental lactogen, and pregnancy-specific beta-1 glycoprotein, and for the expression of cytokeratin.
J C, Manivel +3 more
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Gestational trophoblastic neoplasms: Morphologic considerations
Human Pathology, 1977Abnormal trophoblastic proliferation is the hallmark of a spectrum of lesions constituting the gestational trophoblastic neoplasms. Rapid proliferation, infiltration, vascular invasion, hematogenous dissemination, and spontaneous regression are features of both normal and neoplastic trophoblast.
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Primary chemotherapy for nonmetastatic gestational trophoblastic neoplasms
American Journal of Obstetrics and Gynecology, 1967Abstract This report summarizes our 7 years' experience in the methotrexate chemotherapy of 58 patients with nonmetastatic gestational trophoblastic neoplasms. Of these patients, 54 (93 per cent) entered sustained complete remission. Three of the remaining 4 patients with methotrexate-resistant disease later entered remission with either hysterectomy
C B, Hammond +4 more
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Worldwide Controversies in Gestational Trophoblastic Neoplasms
International Journal of Gynecology & Obstetrics, 1977ABSTRACTThis article reviews worldwide controversies concerning gestational trophoblastic neoplasms (hydatidiform mole, invasive mole, and choriocarcinoma). The epidemiology, endocrinology, histopathologic grading, classification, diagnosis, treatment, management and follow‐up (including chemotherapy, irradiation, and immunotherapy) of gestational ...
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Gestational trophoblastic neoplasms in homozygous twins.
Obstetrics and gynecology, 1982The occurrence of gestational trophoblastic disease in homozygous twins is described. The correlation between this finding and current genetic hypotheses on the pathogenesis of hydatidiform mole is considered.
C. La Vecchia +3 more
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Gestational trophoblastic neoplasms: Morphologic correlates of therapeutic response
American Journal of Obstetrics and Gynecology, 1978GTN were evaluated histologically in reference to biologic behavior and response to chemotherapy. GTN requiring more intensive, multiple drug chemotherapy usually exhibited increased mitotic activity, nuclear atypias, compact growth of cytotrophoblast, and little maturation, as compared to lesions that responded more favorably.
L, Deligdisch +2 more
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