Results 231 to 240 of about 319,242 (298)

Genetic origin of malignant trophoblastic neoplasms.

Cancer Genetics and Cytogenetics, 1994
The genetic origin of three trophoblastic neoplasms (two choriocarcinomas and a placental site trophoblast tumor (PSTT)] was determined by analysis of the restriction fragment length polymorphism (RFLP) pattern. One choriocarcinoma, which was believed not illogically to have developed from an antecedent complete mole, contained both paternal and ...
T. Arima, T. Imamura, S. Amada, M. Tsuneyoshi, N. Wake   +4 more
semanticscholar   +3 more sources

The biology of gestational trophoblastic neoplasms

, 2015
L. Cole
semanticscholar   +2 more sources

Primary chemotherapy for nonmetastatic gestational trophoblastic neoplasms.

American Journal of Obstetrics and Gynecology, 1967
Abstract This report summarizes our 7 years' experience in the methotrexate chemotherapy of 58 patients with nonmetastatic gestational trophoblastic neoplasms. Of these patients, 54 (93 per cent) entered sustained complete remission. Three of the remaining 4 patients with methotrexate-resistant disease later entered remission with either hysterectomy
C. Hammond, R. Hertz, G. Ross, M. Lipsett, W. Odell   +4 more
semanticscholar   +3 more sources

How we treat relapsed refractory gestational trophoblastic neoplasms—An exciting case series

International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics
Relapsed/refractory gestational trophoblastic neoplasia (RR‐GTN) presents a significant therapeutic challenge, with limited options available for patients who fail first‐line treatments.
Kritthivasan Venkatakrishnan, Jayachandran Perumal Kalaiyarasi, Jayashree Natarajan, Amy Jose, U. Wakpaijan, G. Selvarajan, S. Velusamy   +6 more
semanticscholar   +1 more source

Metastatic Adnexal Trophoblastic Neoplasm

Journal of Computer Assisted Tomography, 1988
We report a case of pathologically proven metastatic trophoblastic neoplasm involving the adnexa which occurred after dilatation and curettage and chemotherapy. Duplex doppler ultrasound demonstrated increased vascularity in the adnexa. Angiography was sensitive but did not decisively distinguish between tumor in the adnexa and arteriovenous fistula in
D R, Mirich, J T, Hall, W L, Kraft, M, Santamaria, C, Charnsangavej   +4 more
openaire   +2 more sources

Intermediate Trophoblast in Germ Cell Neoplasms

The American Journal of Surgical Pathology, 1987
One-hundred-twenty-four germ cell tumors and 11 gestational choriocarcinomas were assessed immunohistochemically for the presence of the following placental markers: human chorionic gonadotrophin, human placental lactogen, and pregnancy-specific beta-1 glycoprotein, and for the expression of cytokeratin.
J C, Manivel, G, Niehans, M R, Wick, L P, Dehner   +3 more
openaire   +2 more sources

Gestational trophoblastic neoplasms: Morphologic considerations

Human Pathology, 1977
Abnormal trophoblastic proliferation is the hallmark of a spectrum of lesions constituting the gestational trophoblastic neoplasms. Rapid proliferation, infiltration, vascular invasion, hematogenous dissemination, and spontaneous regression are features of both normal and neoplastic trophoblast.
openaire   +2 more sources

Gestational trophoblastic neoplasms in homozygous twins.

Obstetrics and gynecology, 1982
The occurrence of gestational trophoblastic disease in homozygous twins is described. The correlation between this finding and current genetic hypotheses on the pathogenesis of hydatidiform mole is considered.
C. La Vecchia, S. Franceschi, M. Fasoli, C. Mangioni   +3 more
openaire   +2 more sources

Gestational trophoblastic neoplasms: Morphologic correlates of therapeutic response

American Journal of Obstetrics and Gynecology, 1978
GTN were evaluated histologically in reference to biologic behavior and response to chemotherapy. GTN requiring more intensive, multiple drug chemotherapy usually exhibited increased mitotic activity, nuclear atypias, compact growth of cytotrophoblast, and little maturation, as compared to lesions that responded more favorably.
L, Deligdisch, S G, Driscoll, D P, Goldstein   +2 more
openaire   +2 more sources

Trophoblastic neoplasms: occult disease.

Obstetrics and gynecology clinics of North America, 1989
Occult choriocarcinoma may be associated with low or undetectable levels of human chorionic gonadotropin. This article reviews the various methods of identifying the foci of choriocarcinoma that are currently available.
openaire   +1 more source