Results 61 to 70 of about 122,259 (237)

Etiopathogenetic frontiers of trophoblastic neoplasms: a comprehensive review [PDF]

Universitatea de Stat de Medicină şi Farmacie „Nicolae Testemiţanu”, Chişinău, Republica MoldovaIntroduction. Trophoblastic neoplasms, a heterogeneous group of gestational trophoblastic diseases, present intricate challenges in deciphering their ...
Zingan, Mihaela
core   +1 more source

Epithelioid trophoblastic tumor

Taiwanese Journal of Obstetrics & Gynecology, 2015
Objective: To describe a case of epithelioid trophoblastic tumor (ETT) in a postmenopausal woman, which had several peculiar features that differentiate it from previously reported ETTs.
Sevinc Hallac Keser, Sermin Coban Kokten, Caglar Cakir, Sibel Sensu, Esra Esim Buyukbayrak, Nimet Karadayi   +5 more
doaj   +1 more source

Exposure‐Response Analyses of Datopotamab Deruxtecan (Dato‐DXd), a TROP2‐Directed Antibody‐Drug Conjugate, in Advanced Non‐small Cell Lung Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Exposure‐response analyses supported a favorable benefit‐risk profile of Dato‐DXd at 6 mg/kg Q3W in patients with advanced nonsquamous NSCLC. Datopotamab deruxtecan (Dato‐DXd) is a trophoblast cell‐surface antigen‐2 (TROP2)‐directed antibody‐drug conjugate (ADC) that has demonstrated clinical activity in patients with NSCLC who have received prior ...
Ying Hong, Anna M. Mc Laughlin, Yuzhuo Pan, Sofia Friberg Hietala, Sophie Peigné, Michael Chargualaf, Zoey Tang, Diansong Zhou, Naoyuki Tajima, Malaz Abutarif, Tushar Garimella   +10 more
wiley   +1 more source

Oral Bacterial Extracellular Vesicles as Systemic Messengers: A Mouth–Gut–Systemic Axis Paradigm

Gut Medicine, EarlyView.
ABSTRACT Oral microbiome dysbiosis not only associated with localized periodontal disease but also with multiple systemic diseases, including cardiovascular disease, diabetes mellitus, Alzheimer's disease, rheumatoid arthritis, and cancer. However, the efficiency with which intact viable bacteria cross biological barriers to reach distant organs is ...
Yaping Huang, Narisu Hu, Shuang Pan, Sohaib Shujaat, Zhihui Tang, Hongyang Ma   +5 more
wiley   +1 more source

Tumour Antigen‐Specific Antibody Signatures as Diagnostic Biomarkers for Melanoma

International Journal of Cancer, EarlyView.
ABSTRACT Early detection of melanoma remains challenging, and minimally invasive diagnostic tools are needed to complement imaging and histopathology. Circulating tumour antigen‐specific antibodies (Abs) are promising biomarkers, but their diagnostic value across melanoma stages is not fully established.
Cristina Vico‐Alonso, Tawany De Carvalho Gil, Maithili Sashindranath, Victoria Mar, Jessica Da Gama Duarte   +4 more
wiley   +1 more source

Oligometastatic breast cancer: A mini review

Indian Journal of Medical and Paediatric Oncology, 2014
With few exceptions such as germ cell tumors, trophoblastic neoplasms and colonic cancers, metastatic solid tumors are considered largely incurable.
Sameer Rastogi, Seema Gulia, Jyoti Bajpai, Jaya Ghosh, Sudeep Gupta   +4 more
doaj   +1 more source

Longitudinal AMH trajectories, ovarian reserve recovery, and fertility outcomes after multiagent chemotherapy for high‐risk gestational trophoblastic neoplasia: A real‐world cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To characterize anti‐Müllerian hormone (AMH) recovery after multiagent chemotherapy for high‐risk gestational trophoblastic neoplasia (GTN) and evaluate the impact of regimen and hysterectomy. Methods This was a retrospective cohort of 68 high‐risk GTN patients treated with EMA/CO (etoposide, methotrexate, actinomycin D ...
Wei Xue, Tianyi Chen, Yuxiao Wu, Tong Ren, Jun Zhao, Fengzhi Feng, Xirun Wan, Yang Xiang, Junjun Yang   +8 more
wiley   +1 more source

Analysis of Carbohydrates and Glycoconjugates by Matrix‐Assisted Laser Desorption/Ionization Mass Spectrometry: An Update for 2023–2024

Mass Spectrometry Reviews, EarlyView.
ABSTRACT The use of MALDI mass spectrometry for the analysis of carbohydrates and glycoconjugates is a well‐established technique and this comprehensive review is the twelfth update of the original article published in 1999 and brings coverage of the literature to the end of 2024.
David J. Harvey
wiley   +1 more source

KAT8‐Low Osteosarcoma Suppresses Cisplatin Sensitivity via H4K16ac‐Mediated Cell Apoptosis

Med Research, EarlyView.
The scientific significance of this study is highlighted below: (1) Data mining and clinical discovery: These findings establish a direct clinical link between the KAT8–H4K16ac axis and chemotherapy response in osteosarcoma. (2) Multi‐omics and machine‐learning integration: We integrated proteomics and CUT&Tag multi‐omics to elucidate how chromatin ...
Zhenqun Zhao, Guohui Yu, Shikui Wu, Zhiyang Zhang, Keke Wang, Yingxin Xiong, Chao Sun, Haobo Cui, Yuxing Wang, Ziheng Wang, Huiru Zhang, Huiqin Xue, Shibing Guo   +12 more
wiley   +1 more source

Clinico pathological study of gestational trophoblastic disease – A two years study [PDF]

, 2022
Introduction: Gestational trophoblastic disease is one of the most fascinating of all the gynecologic neoplasms partly due to their comparative rarity in western hemisphere but also because of their unique status as tumors derived from the tissues of one
Sajjan Shetty Shalini Somashekhar
core