Results 51 to 60 of about 8,177 (250)
Advanced Science, EarlyView.In trophoblast cells, T/S (TNFα + SM164) activated caspase‐3, which cleaved GSDME to switch apoptosis to pyroptosis, causing cell swelling, membrane rupture, and release of LDH, HMGB1, IL‐1β and IL‐18. These cytokines induced pro‐inflammatory macrophage polarization, which in turn reinforced pyroptotic signaling in trophoblasts, amplifying systemic ...
Baoying Huang +15 more
wiley +1 more source
Biochemical markers in cancer of the ovary : a review [PDF]
, 1990 The ideal tumour marker would be one which is detectable before obvious clinical involvement. A number of biochemical markers have been used to diagnose carcinoma of the ovary.
Cauchi, Maurice N.
core
Advanced Science, EarlyView.Impaired endometrial receptivity contributes to the poor pregnancy outcomes in women with PCOS. The authors found that decreased endometrial IL‐22 levels and disrupted STAT3‐IGFBP5 signaling pathway contributed to impaired endometrial receptivity. Supplementation with IL‐22 or IGFBP5 exerts a protective effect on implantation failure in PCOS‐like mice,
Baoying Liao +13 more
wiley +1 more source
Case Reports in Obstetrics and Gynecology, 2019 We present a complicated case of recurrence of gestational trophoblastic neoplasms (GTN), mixed ETT and choriocarcinoma at an abdominal cesarean scar. This tumor consisted of typical morphologic and immunophenotypic features of ETT and choriocarcinoma ...
Chunyan Zeng +4 more
doaj +1 more source
Epidermal growth factor receptor is a marker for syncytiotrophoblastic cells in testicular germ cell tumors [PDF]
, 2018 The epidermal growth factor receptor (EGFR) has been implicated in the pathogenesis, therapy and prognosis of various tumor types. The aim of this study was to investigate EGFR expression in a large series of testicular germ cell tumors (TGCTs).
Hechelhammer, Lukas +4 more
core
Advanced Science, EarlyView.This study outlines the developmental pipeline of a multiplexed nanozyme‐based lateral flow immunoassay for the purpose of ovarian germ cell tumor detection. It demonstrates the application of a design of experiments optimization approach for nanozyme probe conjugate development.
Aida Abdelwahed +10 more
wiley +1 more source
Oligometastatic breast cancer: A mini review
Indian Journal of Medical and Paediatric Oncology, 2014 With few exceptions such as germ cell tumors, trophoblastic neoplasms and colonic cancers, metastatic solid tumors are considered largely incurable.
Sameer Rastogi +4 more
doaj +1 more source
A potential diagnostic biomarker: Proteasome LMP2/b1i-differential expression in human uterus neoplasm [PDF]
, 2012 Uterine leiomyosarcoma (ULMS) develops more often in the muscle tissue layer of the uterine body than in the uterine cervix. The development of gynecologic tumors is often correlated with female hormone secretion; however, the development of uterine ULMS
Akiko Horiuchi +5 more
core +1 more source
Intraplacental Choriocarcinoma: Rare or Underdiagnosed? Report of 2 Cases Diagnosed after an Incomplete Miscarriage and a Preterm Spontaneous Vaginal Delivery [PDF]
, 2017 Intraplacental choriocarcinoma is a rare malignant tumor diagnosed after an abortion, an ectopic pregnancy, or a term or preterm pregnancy or following the diagnosis of a hydatidiform mole.
Araújo, Célia +7 more
core +4 more sources
Advanced Science, EarlyView.CellFreeGMF traces plasma cfRNA to likely originating cell types by integrating single‐cell atlases with graph‐regularized matrix factorization. The method decomposes cfRNA profiles into sample–cell contributions to reconstruct pseudo single‐cell expression.
Wenxiang Zhang +9 more
wiley +1 more source