Results 111 to 120 of about 266,561 (263)

Rising XDR-Typhoid Fever Cases in Pakistan: Are We Heading Back to the Pre-antibiotic Era?

open access: yesFrontiers in Public Health, 2022
Muhammad Hammad Butt   +9 more
doaj   +1 more source

Bioactivity profiles of progressively ring‐fluorinated cyclohexyl motifs in the WKYMVm peptide as formylpeptide FPR2 agonists and in keto‐piperazines as anti‐trypanosome agents.

open access: yesChemBioChem, Accepted Article.
A series of all‐cis ring fluorinated cyclohexylalanines with progressively increasing levels of vicinal fluorines, as well as 4‐fluorophenylalanine and pentafluoroarylphenylalanine were introduced into the WKYMVm peptide in place of its tyrosine residue, for assays against the G‐protein coupled formylpeptide receptor, FPR2.
David O'Hagan   +6 more
wiley   +1 more source

TROPICAL DISEASES. [PDF]

open access: green
J. Temperley Gray
openalex   +1 more source

Comparative Analysis of Septin Modifiers, Forchlorfenuron and UR214‐9, on Mitochondrial Fragmentation and Lytic Cell Death

open access: yesCytoskeleton, EarlyView.
ABSTRACT Septins are conserved GTP‐binding proteins that play key roles in cell division, mitochondrial dynamics and immune responses. Despite their importance to human health, pharmacological compounds to modify septins remain limited. Forchlorfenuron (FCF) was the first small molecule identified to modify septins, disrupting their organisation and ...
Dominik Brokatzky   +4 more
wiley   +1 more source

Antiprotozoal Activity of Highly Substituted Pyrazole and Pyrimidine Derivatives

open access: yesChemMedChem, EarlyView.
Based on previously identified antimalarial agents, a series of highly substituted pyrazole and pyrimidines derivatives has been synthesized and tested for antiplasmodial and antileishmanial activity. Selected derivatives show promising antiplasmodial effect with a predicted favorable pharmacokinetic profile.
Matteo Lusardi   +7 more
wiley   +1 more source

The Impact of Climate Change on the Performance of Agricultural Companies Worldwide

open access: yesCorporate Social Responsibility and Environmental Management, EarlyView.
ABSTRACT This study examines the impact of climate change on agricultural firms, focusing on physical risks, both chronic (e.g., temperature and precipitation) and acute (e.g., droughts and floods). We conduct a panel data analysis of 19,929 companies in 69 countries across five continents from 2013 to 2021.
Karen Serrano   +3 more
wiley   +1 more source

Holocene development of submerged keep‐up patch reefs on Bermuda without acroporids: A model of future reef accretion

open access: yesThe Depositional Record, EarlyView.
Bermuda patch reefs development was primarily controlled by massive coral framework construction, and variation in environmental energy, turbidity and bioerosion. These factors shaped the size, diversity and preservation of the framework, leading to a suppressed, steady vertical accretion.
Eduardo Islas‐Dominguez   +2 more
wiley   +1 more source

Is noma a neglected/overlooked tropical disease? [PDF]

open access: yesTrans R Soc Trop Med Hyg, 2022
Feller L, Lemmer J, Khammissa RAG.
europepmc   +1 more source

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