Results 161 to 170 of about 266,561 (263)

Natural Products Targeting Protein Disulfide Isomerases: New Frontiers for Diabetes, Cancer, and Coagulation

open access: yesFood Frontiers, EarlyView.
PDIA4 is significantly upregulated in response to nutrient overload in pancreatic β‐cells, resulting in aberrant ROS production, β‐cell failure, and diabetes. PDIA4 facilitates cancer development by inhibiting caspase‐mediatedcell death in cancer and promoting VEGF‐mediated protumoral immunity andangiogenesis in the tumor microenvironment, highlighting
Yi‐San Lee   +4 more
wiley   +1 more source

River blindness: a devastating yet neglected tropical disease in Africa. [PDF]

open access: yesAnn Med Surg (Lond)
Aborode AT   +17 more
europepmc   +1 more source

Lessons from participatory community mapping to inform neglected tropical disease programmes in Nigeria. [PDF]

open access: yesInt Health, 2023
Lar LA   +15 more
europepmc   +1 more source

Curcuma comosa‐Derived Diarylheptanoid Ameliorates Ulcerative Colitis by Inhibiting JNK/NF‐κB and Activating AMPK/Nrf2 Pathways

open access: yesFood Frontiers, EarlyView.
In this study, we isolated and investigated the protective effect of 1,7‐diphenyl‐(6E)‐6‐hepten‐3‐ol (DPHP) against ulcerative colitis. Our results demonstrate that DPHP administration effectively alleviates colitis symptoms, inhibits inflammation, and strengthens antioxidant defense mechanisms. A combination of network pharmacology analysis, molecular
Van‐Long Truong   +2 more
wiley   +1 more source

Cardiogenic shock requiring VA‐ECMO therapy in scorpionism‐induced myocarditis

open access: yes
ESC Heart Failure, EarlyView.
Alba I. Violino   +5 more
wiley   +1 more source

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