Results 81 to 90 of about 737,374 (318)

AIEgen‐Based Proactive Early Warning System and Precise Treatment Strategy for Monkeypox Prevention and Control

Advanced Science, EarlyView.
An intelligent early warning and treatment system for monkeypox, utilizing a sprayable AIEgen‐ liquid dressing (AIE@LD) that responds to lesion pH. Integrated with a smartphone app and cloud platform, it enables real‐time infection detection via fluorescence imaging and triggers on‐demand photodynamic therapy under white light, effectively eradicating ...
Wei Wang, Zining Liu, Mengjun Li, Judun Zheng, Ruilin Zhang, Ke Liu, Xiaoxue Li, Shaoying Wen, Jingze Yu, Meijia Pan, Fengbo Ma, Kun Zhou, Zheng Zhao, Chenguang Shen, Yuhui Liao   +14 more
wiley   +1 more source

The impact of community-wide, mass drug administration on aggregation of soil-transmitted helminth infection in human host populations

Parasites & Vectors, 2020
Background Soil-transmitted helminths (STH) are intestinal parasites estimated to infect over 1.5 billion people. Current treatment programmes are aimed at morbidity control through school-based deworming programmes (targeting school-aged children, SAC ...
Marleen Werkman, James E. Wright, James E. Truscott, William E. Oswald, Katherine E. Halliday, Marina Papaiakovou, Sam H. Farrell, Rachel L. Pullan, Roy M. Anderson   +8 more
doaj   +1 more source

The Promise of Priority Review Vouchers as a Legislative Tool to Encourage Drugs for Neglected Diseases [PDF]

, 2013
Despite the intellectual property system’s success in promoting the economic well-being of the United States, this system has not achieved all socially valuable ends.
Hamming, Lesley
core   +1 more source

Pan2‐Pan3 Complex‐Mediated Deadenylation Enforces mRNA Quality Control for Infection of the Rice Blast Fungus

Advanced Science, EarlyView.
Discovery that deadenylation, rather than transcription, acts as the rate‐limiting step for developmental timing in a plant pathogen. Evidence that P‐body integrity and mRNA decay are mechanistically coupled to rapid cellular differentiation under environmental stress. Identification of Pan2‐Pan3 as a pathogen‐specific “meta‐virulence factor” absent in
Ziwei Lv, Junting Feng, Shenxian Zhou, Zhiguang Qu, Jun Peng, Xiao‐Lin Chen, Deng Chen   +6 more
wiley   +1 more source

Fighting Zoonotic, Rabies and Public Health in Colonial India [PDF]

, 2019
Rabies is the oldest Zoonotic diseases in the world and one of the most important Zoonotic diseases in India. It was one of the most difficult problems confronted both by the medical and veterinary authorities in colonial India.
Rahaman, S. M. (Sk)
core   +3 more sources

SIRT5–RAC2 Axis Drives Monocyte‐to‐Macrophage Differentiation to Promote Inflammatory Injury in Premature Ovarian Insufficiency

Advanced Science, EarlyView.
SIRT5 desuccinylates and stabilizes RAC2, activating CSF1R‐dependent signaling to drive monocyte differentiation into M0 macrophages and their polarization toward pro‐inflammatory M1 phenotypes in CTX‐induced premature ovarian insufficiency. Inhibiting the SIRT5‐RAC2 axis attenuates inflammation, reduces granulosa cell apoptosis, and preserves ...
Wenjing TanTai, Yaqi Li, Shengnan Liu, Minjuan Wu, Zhixiao Liu, Junfeng Jiang, Jingjing Chen, Xiaoding Xu, Li Li, Chaoqun Li, Fang Zhao, Ye Liu, Haitao Ni, Tengfei Zhang, Mingjuan Xu, Chaofeng Han   +15 more
wiley   +1 more source

Commodity culture : tropical health and hygiene in the British Empire [PDF]

, 2008
Before heading to a 'tropical' region of the Empire, British men and women spent considerable time and effort gathering outfit believed essential for their impending trip.
Johnson, Ryan
core   +2 more sources

CD147/Basigin: From Integrative Molecular Hub to Translational Therapeutic Target

Advanced Science, EarlyView.
This review conceptualizes CD147 as a fundamental “Energy‐Structure Coupler,” physically bridging metabolic flux (via MCTs) with morphogenetic plasticity (via integrins/MMPs) to drive cancer, infection, and autoimmunity. Addressing the “specificity paradox” that limits current translation, the authors chart a strategic roadmap—spanning logic‐gated ...
Xiang‐Min Yang, Huijie Bian, Zhi‐Nan Chen   +2 more
wiley   +1 more source

Social sciences research in neglected tropical diseases 3: Investment in social science research in neglected diseases of poverty: a case study of Bill and Melinda Gates Foundation [PDF]

, 2011
This article has been made available through the Brunel Open Access Publishing Fund.BACKGROUND: The level of funding provides a good proxy for the level of commitment or prioritisation given to a particular issue.
C Frank, D McCoy, Daniel Reidpath, DD Reidpath, Gates Foundation, GF Anderson, International Health Group of the Centre for Public Health Research at Brunel University P, IPPPH, JL Leroy, K Buse, M Moran, M Moran, M Parker, P Allotey, Pascale Allotey, PJ Hotez, SH Woolf, Subhash Pokhrel, TDR   +18 more
core   +4 more sources

Improving Timeliness in the Neglected Tropical Diseases Preventive Chemotherapy Donation Supply Chain through Information Sharing: A Retrospective Empirical Analysis [PDF]

, 2021
Elena Kasparis, Yufei Huang, William M. Lin, Christos Vasilakis   +3 more
openalex   +1 more source