Results 121 to 130 of about 973,801 (239)

Exposure‐Response Analyses of Datopotamab Deruxtecan (Dato‐DXd), a TROP2‐Directed Antibody‐Drug Conjugate, in Advanced Non‐small Cell Lung Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Exposure‐response analyses supported a favorable benefit‐risk profile of Dato‐DXd at 6 mg/kg Q3W in patients with advanced nonsquamous NSCLC. Datopotamab deruxtecan (Dato‐DXd) is a trophoblast cell‐surface antigen‐2 (TROP2)‐directed antibody‐drug conjugate (ADC) that has demonstrated clinical activity in patients with NSCLC who have received prior ...
Ying Hong, Anna M. Mc Laughlin, Yuzhuo Pan, Sofia Friberg Hietala, Sophie Peigné, Michael Chargualaf, Zoey Tang, Diansong Zhou, Naoyuki Tajima, Malaz Abutarif, Tushar Garimella   +10 more
wiley   +1 more source

Embryonic development of the Mediterranean starfish Hacelia attenuata

Developmental Dynamics, EarlyView.
Abstract Background Starfish play essential ecological roles as predators and ecosystem regulators; however, detailed developmental descriptions exist for only a handful of species, none of which are from the Mediterranean Sea. Results In this study, we provide the first full account of the development of the Mediterranean starfish Hacelia attenuata ...
Silvia Caballero‐Mancebo, Laurent Gilletta, Janet Chenevert, Stefania Castagnetti   +3 more
wiley   +1 more source

Biotic and abiotic drivers of ecosystem functioning differ between a temperate and a tropical region

Ecography, EarlyView.
Any single ecosystem will provide many ecosystem functions. Yet, we lack large‐scale, systematic studies of how abiotic factors can directly or indirectly – via effects on biodiversity – drive ecosystem functioning. In this study, we assessed the impact of climate, landscape and biotic community on ecosystem functioning in the temperate and tropical ...
Laura J. A. van Dijk, Andreia Miraldo, Dimby Raharinjanahary, Eric Tsiriniaina Rajoelison, Brian L. Fisher, Robert M. Goodsell, Elzbieta Iwaszkiewicz‐Eggebrecht, David Åhlén, Johanna Högvall, Erika Lundberg, Emma Rova, Piotr Łukasik, Fredrik Ronquist, Tomas Roslin, Ayco J. M. Tack   +14 more
wiley   +1 more source

Associations between mycorrhizal dominance and woody species diversity shift with stand development and climate across subtropical and tropical forests in Taiwan

Ecography, EarlyView.
Mycorrhizal symbioses influence woody species diversity, but whether this association shifts with forest stand development remains underexplored. Using forest inventory data across subtropical and tropical forests in Taiwan, we found that woody species diversity was lower in ectomycorrhizal (EM)‐dominated than in arbuscular mycorrhizal (AM)‐dominated ...
Albert Vilà‐Cabrera, Julen Astigarraga, Kirsten S.W. O'Sullivan, Karina E. Clemmensen, Henna Tyyskä, Sarah Greenwood, Josep Padullés Cubino, Jan‐Chang Chen, Alistair S. Jump   +8 more
wiley   +1 more source

Scale‐dependent assembly shapes taxon‐dependent responses of soil microbes to island isolation and area

Ecography, EarlyView.
The theory of island biogeography (TIB) remains contentious for microbes, as their immense dispersal potential and microscopic size may decouple diversity from classic isolation/area effects. We explicitly tested TIB scaling rules for soil bacteria and fungi across 20 oceanic islands using a rigorous multi‐scale framework that integrated high ...
Lan Liu, Zuzana Münzbergová, Lele Jiang, Long Chen, Shurong Zhou   +4 more
wiley   +1 more source

Nested Carbon Governance in Southeast Asia: Towards Just Nature‐Based Solutions?

Environmental Policy and Governance, EarlyView.
ABSTRACT Nature‐based solutions (NbS) have gained prominence as an integrated approach to addressing climate change and biodiversity loss while supporting sustainable development. Yet, their implementation across Southeast Asia remains fragmented and often contested.
Helena Varkkey, Michelle Ann Miller, David Taylor   +2 more
wiley   +1 more source

Escalating Fire-Driven Forest Loss in Protected Tropical Forests. [PDF]

Glob Chang Biol
Bousfield CG, Morton O.
europepmc   +1 more source

The Power to Care for Oneself: Power Increases Self‐Compassion

European Journal of Social Psychology, EarlyView.
ABSTRACT Sense of power and self‐compassion both impact important intrapsychic and interpersonal outcomes. However, how powerholders treat themselves when experiencing failure or personal setbacks is unclear. We propose that powerholders are more apt than their lower‐power counterparts to exhibit self‐compassion when faced with difficulties. Across six
Robert Körner, Astrid Schütz, Lars‐Eric Petersen, Marine Groulon, Serena Chen   +4 more
wiley   +1 more source

Heatwaves favour acyclic monoterpene emissions in tropical forests. [PDF]

Nat Commun
Zeng J, Wang X, Lu Y, Pang W, Song W, Zhang Y, Peng P, Wang X.   +7 more
europepmc   +1 more source

Predicting Solar Photovoltaic Power Output in Saudi Arabia's Jazan Region: Performance Comparison of Machine Learning Models

Energy Science &Engineering, EarlyView.
Workflow of the PV power estimation and ML forecasting methodology. ABSTRACT Accurate prediction of solar panel energy output is vital for managing power systems effectively and maintaining a stable electrical grid. This is especially important in regions that rely heavily on renewable sources. This research provides a direct comparison of five machine
Abdoalateef Alzhrani, Abdullahi Abubakar Mas'ud, Mohd Khairul Amri Kamarudin, Firdaus Muhammad‐Sukki, Abdullahi Mohammad   +4 more
wiley   +1 more source