Results 101 to 110 of about 3,312,399 (332)

Pan2‐Pan3 Complex‐Mediated Deadenylation Enforces mRNA Quality Control for Infection of the Rice Blast Fungus

open access: yesAdvanced Science, EarlyView.
Discovery that deadenylation, rather than transcription, acts as the rate‐limiting step for developmental timing in a plant pathogen. Evidence that P‐body integrity and mRNA decay are mechanistically coupled to rapid cellular differentiation under environmental stress. Identification of Pan2‐Pan3 as a pathogen‐specific “meta‐virulence factor” absent in
Ziwei Lv   +6 more
wiley   +1 more source

Utilidad del cefadroxilo en leishmaniosis tegumentaria americana con infecciones piógenas sobreagregadas

open access: yesKasmera, 2009
: Cutaneous leishmaniosis of the New World (CLNW) is a health problem in rural areas of Venezuela. Patients with muco-cutaneous ulcers tend to present intercurrent infections of the lesions by pyogenic bacteria.
Navarro Pedro   +6 more
doaj  

The global fight to develop antipoverty vaccines in the anti-vaccine era

open access: yesHuman Vaccines & Immunotherapeutics, 2018
Antipoverty vaccines are the vaccines targeting a group of approximately 20 neglected tropical diseases (NTDs), as currently defined by the World Health Organization (WHO).
Peter J. Hotez
doaj   +1 more source

Compliance with focused antenatal care services: do health workers in rural Burkina Faso, Uganda and Tanzania perform all ANC procedures? [PDF]

open access: yes, 2012
\ud \ud To assess health workers' compliance with the procedures set in the focused antenatal care (ANC) guidelines in rural Uganda, Tanzania and Burkina Faso; to compare the compliance within and among the three study sites; and to appraise the logistic
Anya   +37 more
core   +1 more source

Combination Immunotherapy as a Promising Strategy to Overcome Immunotherapy Resistance: From Emergence to Next‐Generation Approaches

open access: yesAdvanced Science, EarlyView.
This review examines emerging combination immunotherapy strategies tailored to distinct tumor microenvironments and highlights next‐generation biomarkers that guide response prediction and treatment personalization. It integrates lessons from unsuccessful trials, addresses toxicity challenges, and outlines approaches for early biomarker discovery and ...
Asmita Pandey   +6 more
wiley   +1 more source

Euphorbia tirucalli L. (Euphorbiaceae): the miracle tree: current status of available knowledge [PDF]

open access: yes, 2011
Euphorbia tirucalli is one of the most important tree Euphorbias known worldwide for its many uses. Endemic to tropical Africa where it often grows wild, it is usually planted for boundary demarcation but also as a live fence around compounds, shrines ...
Mwine, Tedson Julius, Van Damme, Patrick
core   +1 more source

The development of a multi-criteria decision analysis aid to help with contraceptive choices: My Contraception Tool.

open access: yes, 2013
My Contraception Tool (MCT) applies the principles of multi-criteria decision analysis to the choice of contraceptive method. Its purpose is to make the decision-making process transparent to the user and to suggest a method to them based on their own ...
Cowan, Frances M   +3 more
core   +1 more source

Rapid malaria diagnostic tests vs. clinical management of malaria in rural Burkina Faso: safety and effect on clinical decisions. A randomized trial [PDF]

open access: yes, 2009
OBJECTIVES: To assess if the clinical outcome of patients treated after performing a Rapid Diagnostic Test for malaria (RDT) is at least equivalent to that of controls (treated presumptively without test) and to determine the impact of the introduction ...
Beiersmann   +19 more
core   +2 more sources

Coronavirus Nsp3 Hijacks CLTC to Modulate Autophagosome Nucleation for Promoting DMV Formation and Viral Replication

open access: yesAdvanced Science, EarlyView.
In wild‐type cells, FIPV infection recruits CLTC to nsp3, facilitates DMV biogenesis and block autophagic flux to promote viral replication. CLTC knockout impairs autophagosome nucleation by reducing Beclin1–ATG14 complex expression. This disrupts the formation of autophagic precursor membranes, thereby preventing their hijacking by nsp3 for DMV ...
Juan Xu   +9 more
wiley   +1 more source

The man from the stars: a narrative approach to neglected diseases

open access: yesItalian Journal of Medicine
In this narrative medicine essay, a young migrant suffering from schistosomiasis unveils his story and his journey from Africa to the Alps. The hardships of a long voyage and the clinical history of the disease are described, combining the form of ...
Paolo Agostinis   +3 more
doaj   +1 more source

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