Results 111 to 120 of about 3,312,399 (332)

Dynamic Shifts in ER–Plasma Membrane Junctions Signaling Define Pro‐Metastatic N‐Glycosylation and Predict Prostate Cancer Progression

open access: yesAdvanced Science, EarlyView.
Prostate cancer remains a leading cause of male cancer death, yet screening cannot reliably identify aggressive disease, underscoring the need for tissue biomarkers. It is shown that primary tumors increase ER–plasma membrane junction signaling via STIM1/ORP5, whereas metastasis features their loss, Golgi dispersal, and rapid conversion of high‐mannose
Amanda J. Macke   +14 more
wiley   +1 more source

WHO Framework Convention on Tobacco Control [PDF]

open access: yes, 2012
Annotated and edited transcript of a Witness Seminar in collaboration with the Department of Kowledge Management and Sharing, WHO, held in Geneva, 26 February 2010.
REYNOLDS, LA, TANSEY, EM
core  

Demographic characteristics and opportunistic diseases associated with attrition during preparation for antiretroviral therapy in primary health centres in Kibera, Kenya. [PDF]

open access: yes, 2011
Using routine data from HIV-positive adult patients eligible for antiretroviral therapy (ART), we report on routinely collected demographic characteristics and opportunistic diseases associated with pre-ART attrition (deaths and loss to follow-up). Among
Amuron   +20 more
core   +2 more sources

Bioinspired Engineering of Streamlined Skeletal Interoception: Neural Bioprinted Piezoelectric Scaffolds for Neuro‐Vascularized Bone Regeneration

open access: yesAdvanced Science, EarlyView.
This study develops neural bioprinted piezoelectric scaffolds which construct local “sensor‐effector” circuit, inspired by the skeletal interoception system. Upon US stimulation sensing and mechanoelectrical coupling by PLLA nanofibers, the incorporated DRG neurons effect through Ca2+ influx‐induced enhanced secretion and expression of CGRP.
Yingze Su   +18 more
wiley   +1 more source

O Brasil e a medicina tropical

open access: yesRevista de Saúde Pública
São feitas considerações sobre o papel das endemias tropicais no desenvolvimento da sociedade brasileira. Aborda-se a atualidade das pesquisas que tratam da temática das doenças infecciosas. Comparando o significado para o primeiro mundo, conclui-se pela
Oswaldo Paulo Forattini
doaj  

Spectrum of Viral Pathogens in Blood of Malaria-Free Ill Travelers Returning to Canada

open access: yesEmerging Infectious Diseases, 2016
Malaria is the most common specific cause of fever in returning travelers, but many other vectorborne infections and viral infections are emerging and increasingly encountered by travelers.
Ruwandi Kariyawasam   +6 more
doaj   +1 more source

British Contributions to Medical Research and Education in Africa after the Second World War [PDF]

open access: yes, 2001
©The Trustee of the Wellcome Trust, London, 2001. First published by the Wellcome Trust Centre for the History of Medicine at UCL, 2001. All volumes are freely available online at: www.history.qmul.ac.uk/research/modbiomed/wellcome_witnesses/Annotated ...
Reynolds, LA, Tansey, EM
core  

Eflornithine is a cost-effective alternative to melarsoprol for the treatment of second-stage human West African trypanosomiasis in Caxito, Angola. [PDF]

open access: yes, 2008
OBJECTIVE: To compare the cost-effectiveness of eflornithine and melarsoprol in the treatment of human African trypanosomiasis. METHOD: We used data from a Médecins Sans Frontières treatment project in Caxito, Angola to do a formal cost-effectiveness ...
Adam   +23 more
core   +2 more sources

Peroxidase‐Mimicking Nanozymes for Rapid Detection of Infectious Diseases

open access: yesAdvanced Science, EarlyView.
Peroxidase‐mimicking nanozymes (PMNs) have emerged as robust and versatile materials for rapid infectious disease diagnostics. This review highlights the rational design and controlled synthesis of PMNs, summarizes key biomarkers relevant to infectious diseases, examines their integration into diverse rapid detection platforms, and highlights ...
Shikuan Shao   +5 more
wiley   +1 more source

Epidemiology, impact and control of rabies in Nepal : a systematic review [PDF]

open access: yes, 2016
Background: Rabies is a vaccine-preventable viral zoonosis belonging to the group of neglected tropical diseases. Exposure to a rabid animal may result in a fatal acute encephalitis if effective post-exposure prophylaxis is not provided.
Ale, Anita   +13 more
core   +4 more sources

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