Results 201 to 210 of about 693,756 (350)

London School of Hygiene and Tropical Medicine [PDF]

, 2008

core  

Could the Biological Potency of Porcelia macrocarpa R.E. Fries (Annonaceae) be Linked to Its Diverse Metabolite Profile?

Chemistry &Biodiversity, EarlyView.
ABSTRACT Porcelia macrocarpa is a Brazilian plant species belonging to the Annonaceae family. To date, more than 190 compounds have been identified and/or isolated from this species, with terpenoids comprising the majority (62%). Alkaloids represent the second most abundant class (11%), followed by steroids (4%), acetogenins (4%), fatty acids (4 ...
Fernanda Thevenard, Ivanildo A. Brito, Emerson A. Oliveira, Mariana H. Chaves, João Henrique G. Lago   +4 more
wiley   +1 more source

Lipocalin‐2 activates hepatic stellate cells and promotes nonalcoholic steatohepatitis in high‐fat diet–fed Ob/Ob mice

Hepatology, EarlyView., 2022
Graphical summary of obesity‐induced NASH progression by LCN2 targeted to HSC activation. Abstract Background and Aims In obesity and type 2 diabetes mellitus, leptin promotes insulin resistance and contributes to the progression of NASH via activation of hepatic stellate cells (HSCs).
Kyung Eun Kim, Jaewoong Lee, Hyun Joo Shin, Eun Ae Jeong, Hye Min Jang, Yu Jeong Ahn, Hyeong Seok An, Jong Youl Lee, Meong Cheol Shin, Soo Kyoung Kim, Won Gi Yoo, Won Ho Kim, Gu Seob Roh   +12 more
wiley   +1 more source

Diagnosis, management and prevention of loiasis: guideline of the German Society for Tropical Medicine, Travel Medicine, and Global Health (DTG). [PDF]

Infection
Ramharter M, Schlabe S, Hübner MP, Michelitsch P, Kurth F, Bélard S, Nordmann T, Davi SD.   +7 more
europepmc   +1 more source

Fungal Biodiversity From the Atlantic Forest With Bioactive Metabolites Against Cutaneous Leishmaniasis

Chemistry &Biodiversity, EarlyView.
ABSTRACT Biodiversity offers a rich source of bioactive compounds for drug discovery. We isolated Aspergillus fumigatus from compost in the Atlantic Forest and found its extract active against Leishmania (Leishmania) amazonensis. Two crude extracts, I06 and I75, were selected for further study.
Juliana Cristina Pereira Calado, Marina Valente Navarro, Alison Felipe Alencar Chaves, Isis Casula, Patricia Locosque Ramos, João Batista da Cruz, Anderson Messias Rodrigues, Keith Dayane Leite Lira, Fernando Luiz Affonso Fonseca, Patricia Xander, Suzan Pantaroto de Vasconcellos, Wagner Luiz Batista   +11 more
wiley   +1 more source

Adeno‐associated virus serotype 2 capsid variants for improved liver‐directed gene therapy

Hepatology, EarlyView., 2022
Abstract Background and Aims Current liver‐directed gene therapies look for adeno‐associated virus (AAV) vectors with improved efficacy. With this background, capsid engineering is explored. Whereas shuffled capsid library screenings have resulted in potent liver targeting variants with one first vector in human clinical trials, modifying natural ...
Nadja Meumann, Marti Cabanes‐Creus, Moritz Ertelt, Renina Gale Navarro, Julie Lucifora, Qinggong Yuan, Karin Nien‐Huber, Ahmed Abdelrahman, Xuan‐Khang Vu, Liang Zhang, Ann‐Christin Franke, Christian Schmithals, Albrecht Piiper, Annabelle Vogt, Maria Gonzalez‐Carmona, Jochen T. Frueh, Evelyn Ullrich, Philip Meuleman, Steven R. Talbot, Margarete Odenthal, Michael Ott, Erhard Seifried, Clara T. Schoeder, Joachim Schwäble, Leszek Lisowski, Hildegard Büning   +25 more
wiley   +1 more source

A combined tropical medicine and psychiatry approach to patients with possible delusional infestation. [PDF]

Trans R Soc Trop Med Hyg
Squire SB, Taegtmeyer M, Javed Q, O'Dempsey T, Kullu C, Lepping P.   +5 more
europepmc   +1 more source

Untargeted Metabolomics Reveals Seasonal and Tissue‐Specific Metabolic Shifts in Holothuria cinerascens

Chemistry &Biodiversity, EarlyView.
Untargeted metabolic profiling of three body tissues from Holothuria cinerascens in South Africa using 1H‐NMR and UPLC–QTOF–MS revealed distinct tissue‐specific and seasonal metabolic variations, with the body wall and gut/mesentery exhibiting high metabolite diversity.
Cassandra Upton, Gerhard Prinsloo, Paul Steenkamp, Moses Okpeku   +3 more
wiley   +1 more source

Comprehensive Tropical Medicine Text

Canadian Journal of Infectious Diseases, 1992
Ross A Pennie
doaj   +1 more source

Evaluation of molecular and serological testing for imported urogenital schistosomiasis screening in a referral tropical medicine centre in Barcelona, Spain. [PDF]

Parasit Vectors
Martínez-Vallejo P, Mediavilla A, Silgado A, Zarzuela F, Goterris L, Maturana CR, Serre-Delcor N, Oliveira-Souto I, Salvador F, Joseph-Munne J, Aznar ML, Pou D, Treviño B, Molina I, Sotillo J, Sulleiro E.   +15 more
europepmc   +1 more source