Results 81 to 90 of about 3,312,399 (332)

Adherence to the combination of sulphadoxine-pyrimethamine and artesunate in the Maheba refugee settlement, Zambia. [PDF]

, 2004
Artemisinin-based combination therapy (ACT) is one strategy recommended to increase cure rates in malaria and to contain resistance to Plasmodium falciparum. In the Maheba refugee settlement, children aged 5 years or younger with a confirmed diagnosis of
Balkan, S, Depoortere, E, Fermon, F, Guthmann, J P, Legros, D, Nkandu, E, Sipilanyambe, N   +6 more
core   +2 more sources

Testicular mRNA‐LNP Delivery: A Novel Therapy for Genetic Spermatogenic Disorders

Advanced Science, EarlyView.
In the current study, we developed a novel therapy for genetic spermatogenic disorders. It was revealed that in vivo delivery of mRNA LNP3 could restore spermatogenesis in Msh5D486Y/D486Y and Maps KO mouse models with meiotic arrest. Notably, the offspring without genomic integration was born using ICSI derived from the rescue of Msh5D486Y/D486Y mouse ...
Chenwang Zhang, Nan Liang, Wenbo Li, Shuai Xu, Peng Li, Wanze Ni, Na Li, Sha Han, Ningjing Ou, Haowei Bai, Yuxiang Zhang, Furong Bai, Yifan Sun, Dewei Qian, Xinjie Bu, Erlei Zhi, Ruhui Tian, Yuhua Huang, Jingpeng Zhao, Fujun Zhao, Hao Chen, Zheng Li, Chencheng Yao   +22 more
wiley   +1 more source

Low efficacy of the combination artesunate plus amodiaquine for uncomplicated falciparum malaria among children under 5 years in Kailahun, Sierra Leone. [PDF]

, 2006
OBJECTIVE: In 2004, Sierra Leone adopted artesunate plus amodiaquine as first-line antimalarial treatment. We evaluated the efficacy of this combination in Kailahun, where a previous study had shown 70.2% efficacy of amodiaquine in monotherapy.
Balkan, S, Checchi, F, Durand, R, Grandesso, F, Guthmann, J P, Hagerman, A, Kamara, S, Lam, E, Scollo, G   +8 more
core   +2 more sources

The Osteoblastic Microenvironment Determines the Fate of Breast Cancer Cells Disseminated in the Bone Marrow

Advanced Science, EarlyView.
This study revealed how the osteoblastic microenvironment determines the fate of cancer cells disseminated in bone, with a focus on whether they colonize, reside in quiescence, or reactivate from dormancy. Targeting integrin signaling may offer promising strategies for preventing quiescent cancer cells reactivation and bone colonization.
Hong‐Li Wang, Rui Zhang, Xiao‐Min Yue, Jie Zhou, Yu‐Fan Huang, Rong Meng, Yu‐Li Wang, Xiao‐Qing Li   +7 more
wiley   +1 more source

Tri–Band and Dual–Response Smart Windows With Asymmetric Mid–Infrared Emissivity for Year–Round Energy Conservation

Advanced Science, EarlyView.
Our promising smart window exhibits exceptional optical properties, enabling the indoor temperature reduction of 12°C during summer and delivering the annual energy savings of 14.2%–24.4% across mid–to–low latitudes. ABSTRACT Building energy consumption accounts for 20%–40% of global energy usage, with windows among the least energy–efficient ...
Cheng Wang, Junwei Liu, Zhihua Zhou, Yuechao Chao, Xueqing Yang, Yan Liang, Yifan Zhou, Weiyi Zhang, Yahui Du, Wufan Wang, Shuqi Zhang, Jinyue Yan   +11 more
wiley   +1 more source

Study of virgin coconut oil cost and yield by using natural method fermentation [PDF]

, 2020
Coconut has existed for at least thousands of years. Its flesh, its husk, its shell and its milk can be used for different purposes. Most importantly, coconut oil has been applied in numerous applications such as cosmetics, cooking ingredient and ...
Abd Rahman, Misbahul Muneer, Fadzil, Muhammad Ihsanuddin, Kamalrulzaman, Muhammad Daniel Haikal, Md Maarof, Mohd Zulariffin, Noh, Nur Syaza Hanim, Roslan, Muhammad Sufi   +5 more
core  

Efficacy and effectiveness of the combination of sulfadoxine/pyrimethamine and a 3-day course of artesunate for the treatment of uncomplicated falciparum malaria in a refugee settlement in Zambia. [PDF]

, 2005
In the Maheba Refugee Settlement, in the clinics supported by Medecins Sans Frontieres, all children aged up to 5 years with a confirmed diagnosis of uncomplicated falciparum malaria are treated with the combination of sulfadoxine/pyrimethamine (SP) and ...
Bloland PB, Contamin H, National Malaria Control Centre, Nosten F, Peterson DS, Trape JF, Vasconcelos KF, White NJ, World Health Organisation (WHO), World Health Organisation (WHO)   +9 more
core   +2 more sources

Profile of Trypanosoma cruzi Infection in a Tropical Medicine Reference Center, Northern Italy

PLoS Neglected Tropical Diseases, 2014
Background Chagas disease (CD) is endemic in Central and South America, Mexico and even in some areas of the United States. However, cases have been increasingly recorded also in non-endemic countries. The estimated number of infected people in Europe is
F. Gobbi, A. Angheben, M. Anselmi, C. Postiglione, E. Repetto, D. Buonfrate, S. Marocco, S. Tais, A. Chiampan, P. Mainardi, Z. Bisoffi   +10 more
semanticscholar   +1 more source

Profiling of Integrin Isoforms on Lung‐Tropic Exosomes by Spectrally and Kinetically Multiplexed Single‐Molecule Imaging

Advanced Science, EarlyView.
A spectrally and kinetically multiplexed single‐molecule imaging method is developed, which achieved simultaneous imaging of 12 exosomal proteins at an unparalleled single‐copy resolution. It is found that co‐occurrence of α6 integrin and the pairing β counterpart on single exosomes is essential for lung targeting, providing valuable information for ...
Songlin Liu, Haixin Wang, Qin Shentu, Liang Yuan, Jiangshan Tie, Li Li, Rui Ai, Bochen Ma, Lubin Qi, Yifei Jiang, Xiaohong Fang   +10 more
wiley   +1 more source

Rates and Causes of Death in Chiradzulu District, Malawi, 2008: A Key Informant Study [PDF]

, 2010
In September 2008, we measured all-cause mortality in Chiradzulu District, Malawi (population 291 000) over a 60-day retrospective period, using capture-recapture analysis of three lists of deaths provided by (i) key community informants, (ii) graveyard ...
Adjuik, Baiden, Doctor, Fienberg, Hosegood, International Working Group for Disease Monitoring and Forecasting, Jahn, Mathers, Roberts, Setel, World Health Organization   +10 more
core   +2 more sources