Immunopathogenesis of HTLV-I-associated myelopathy/tropical spastic paraparesis
The main pathological feature of human T-lymphotropic virus type I (HTLV-I)-associated myelopathy/tropical spastic paraparesis (HAM/TSP) is chronic inflammation of the spinal cord characterized by perivascular cuffing of mononuclear cells accompanied by parenchymal lymphocytic infiltration. Although the exact mechanism of the pathogenesis of HAM/TSP is
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Neurological manifestations in individuals with HTLV-1-associated myelopathy/tropical spastic paraparesis in the Amazon [PDF]
G A S Dias +7 more
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Center of gravity oscillations in HTLV-1-associated myelopathy/tropical spastic paraparesis [PDF]
Vinícius Cardoso Lago +4 more
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Response to: RSBMT-2018-0270.R2 - Pain and quality of life in human T cell lymphotropic virus type 1 associated myelopathy or tropical spastic paraparesis after home-based exercise protocol: Randomized clinical trial. [PDF]
Macêdo MC +5 more
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Deep sequencing analysis of Human T cell lymphotropic virus type 1 (HTLV-1) long terminal repeat (LTR) region of tropical spastic paraparesis (TSP)/HTLV-1 associated myelopathy (HAM) and asymptomatic carriers [PDF]
Filipe FA Rego +3 more
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Human T Cell Leukemia Virus Type I (HTLV‐I) Infection Induces Greater Expansions of CD8 T Lymphocytes in Persons with HTLV‐I–Associated Myelopathy/Tropical Spastic Paraparesis than in Asymptomatic Carriers [PDF]
Abel Ureta‐Vidal +10 more
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A refractory human T-cell leukemia virus type 1-associated myelopathy/tropical spastic paraparesis patient with lymphoma-type adult T-cell leukemia/lymphoma: A case report and review of the literature. [PDF]
Tamaki K +8 more
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[Tropical spastic paraparesis: a necessary redefinition].
The author disserts on the definition of Tropical Spastic Paraparesis since its first description up to the etiological involvement of HTLV-1 in part of the cases. According to him the basic nucleus of the syndrome consists of a paraparesis with pyramidal signs (spasticity and hyperreflexia) with variable sensory and sphincter symptoms.
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