Results 141 to 150 of about 635,290 (190)

Tropical spastic paraparesis in colombia

Annals of Neurology, 1988
A high-incidence focus of tropical spastic paraparesis (TSP) occurs on the South Pacific coast of Colombia. Of 55 patients studied, 52 (94.5%) had IgG antibodies to the human T-cell lymphotropic virus type I (HTLV-I) in serum and/or cerebrospinal fluid. Control groups did not show similar high positivity.
Vladimir Zaninovic, Cesar Arango, Robin Biojo, Carios Mora, Pamela Rodgers-Johnson, Mauricio Concha, Raul Corral, Pablo Barreto, Isabella Borrero, Ralph M. Garruto, Clarence J. Gibbs, D. Carleton Gajdusek   +11 more
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Tropical spastic paraparesis

2023
A large number of causative agents can result in spinal cord disorders in the tropics including etiologies similar to those of temperate regions such as trauma, spinal bone and disc lesions, tumors, epidural abscess, and congenital malformations. Yet infectious and nutritional disorders differ in their higher prevalence in tropical regions including ...
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Immunological studies in tropical spastic paraparesis

Annals of Neurology, 1990
AbstractTropical spastic paraparesis (TSP) and other chronic‐progressive myelopathies have been clearly associated with increased serum and cerebrospinal fluid antibody titers to human T‐lymphotropic virus type I (HTLV‐I). However, little is known about the cellular immune function in TSP. In the present study, activated T lymphocytes were found in the
S, Jacobson, A, Gupta, D, Mattson, E, Mingioli, D E, McFarlin   +4 more
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The neuroepidemiology of tropical spastic paraparesis

Annals of Neurology, 1988
Recent neuroepidemiological studies of endemic tropical spastic paraparesis (TSP) have confirmed the existence of high-prevalence foci in several tropical islands, including Jamaica and Martinique in the Caribbean, Tumaco off the Pacific coast of Colombia, and the Seychelles in the Indian Ocean.
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The significance of immune disorder in tropical spastic paraparesis

Human Antibodies, 1999
The reports of the occurrence of HTLV-1 infection and/or HTLV-1 associated myelopathy (HAM/tropical spastic paraparesis (TSP) in patients with certain organ-specific and nonorgan-specific autoimmune diseases prompted us to assess the relationship between TSP and humoral autoimmunity.
M F, Smikle, E N, Barton, O C, Morgan, J, Luseko, V E, Bailey, E M, Williams   +5 more
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A clinical neurophysiologic study of tropical spastic paraparesis

Muscle & Nerve, 1988
AbstractDuring a field study in the Seychelles Islands, 19 patients with tropical spastic paraparesis (TSP) were evaluated electrophysiologically. Methods of assessment included motor and sensory nerve conduction studies, electromyography, and analysis of the somatosensory evoked potentials after stimulation of the tibial and median nerves. The results
A C, Ludolph, J, Hugon, G C, Román, P S, Spencer, B S, Schoenberg   +4 more
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Tropical spastic paraparesis: A neuroepidemiological study in Colombia

Annals of Neurology, 1985
AbstractA geographic isolate of tropical spastic paraparesis (TSP) in Tumaco, Colombia, is described. Fifity confirmed cases were identified (29 men, 21 women) with an estimated prevalence rario of 98 cases per 100, 000 population. Patients with identified cases ranged in age from 24 to75 years (mean, 46.5). TSP begins with burning feet, leg stiffness,
G C, Román, L N, Román, P S, Spencer, B S, Schoenberg   +3 more
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Tropical Spastic Paraparesis on the Caribbean Coast of Colombia

The American Journal of Tropical Medicine and Hygiene, 1995
Tropical spastic paraparesis (TSP) is a retroviral disease characterized predominantly by a chronic myelopathy and progressive leg weakness. Four patients from the northern coast of Columbia with chronic spastic paraparesis and serum positivity for antibodies to human T cell lymphotropic virus type 1 by enzyme-linked immunosorbent assay and Western ...
F, Dangond, J S, Daza, A, Rosania, M J, Quin, V, Zaninovic, B, Chaplin, R, Marlink, D A, Hafler   +7 more
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Tropical Spastic Paraparesis

Archives of Neurology, 2001
T ropical spastic paraparesis (TSP), a progressive myelopathy predominantly affecting the lower limbs, is currently synonymous with human T-lymphotropic virus type I (HTLVI)–associated myelopathy/tropical spastic paraparesis (HAM/TSP). At the turn of the 20th century, Drs Henry Strachan and Henry Scott provided the first clinical descriptions of ...
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Clonus Associated with Tropical Spastic Paraparesis

New England Journal of Medicine, 2016
A 53-year-old woman with tropical spastic paraparesis reported several months of worsening weakness of the legs and feet. On examination, she had severe spasticity and weakness of both legs and feet, bilateral Babinski sign, and bilateral patellar clonus, shown in a video.
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