Results 31 to 40 of about 3,170 (177)

Evolution in coeliac disease diagnosis and management. [PDF]

JGH Open
Our understanding of coeliac disease is evolving from a gut‐centric view to recognizing it as a systemic illness driven by an aberrant T cell‐mediated response to gluten. Interest in population screening is growing due to the failure of traditional case finding and reliance on small bowel histology is waning as serologic tests, now validated in both ...
Tye-Din JA.
europepmc   +2 more sources

A clinico-endoscopic and histopathological correlation in suspected cases of malabsorption: A cross-sectional study [PDF]

Journal of Research in Clinical Medicine
Introduction: Malabsorption is a complex medical condition with a diverse range of underlying etiologies posing a diagnostic challenge. The aim of the study was to investigate the correlation between endoscopic findings and histopathological diagnoses in
Sargam Dhaliwal, Mangesh Londhe, Archana Buch, Charusheela Gore, Amol Sonyabapu Dahale, Fatehpal Singh Gill, Reshma Alexander   +6 more
doaj   +1 more source

Clinicopathologic Analysis of Malabsorption Syndrome in a Tertiary Care Center in South India

Medical Journal of Dr. D.Y. Patil Vidyapeeth
Background: Malabsorption syndrome is an umbrella term for manifestations consisting of diarrhea, steatorrhea, malnutrition, unexplained weight loss, persistent or recurrent abdominal pain, and anemia.
Nidhya Ganesan, S. Shrinnivi, R. Shivani, R. K. Kartikayan   +3 more
doaj   +1 more source

European Society for the Study of Coeliac Disease 2025 Updated Guidelines on the Diagnosis and Management of Coeliac Disease in Adults. Part 1: Diagnostic Approach

United European Gastroenterology Journal, Volume 13, Issue 10, Page 1855-1886, December 2025.
Infographic. This infographic summarizes the diagnostic approach to CeD in adults, including initial serological testing, histological confirmation, criteria for a no‐biopsy diagnosis, seronegative CeD, potential CeD, and the role of gluten challenge. Source: Authors' own creation (based on current clinical guidelines).
Abdulbaqi Al‐Toma, Fabiana Zingone, Federica Branchi, Annalisa Schiepatti, Georgia Malamut, Cristina Canova, Isabella Rosato, Honoria Ocagli, Nick Trott, Luca Elli, Alina Popp, Carmen Gianfrani, Renata Auricchio, Andra Neefjes‐Borst, David S. Sanders, Christophe Cellier, Chris J. Mulder, Gerd Bouma, Knut E. A. Lundin, Ludvig M. Sollid, Michael Schumann   +20 more
wiley   +1 more source

Prevalence of Celiac Disease in Patients With Primary Biliary Cholangitis: A Systematic Review and Meta‐Analysis

Liver International, Volume 45, Issue 9, September 2025.
ABSTRACT Celiac disease (CeD) has been linked to both autoimmunity and chronic liver disease, but most data on the link to primary biliary cholangitis (PBC) originate from small studies and have yielded conflicting results. A systematic search was performed in the databases of Medline, Embase, Cochrane and Web of Science Core Collection for studies ...
Fabiana Zingone, Cristina Canova, Anders Forss, Fahim Ebrahimi, Nora Cazzagon, Isabella Rosato, Jonas F. Ludvigsson   +6 more
wiley   +1 more source

Dysgammaglobulinaemia in Tropical Sprue [PDF]

BMJ, 1968
Study of immunoglobulin levels in 16 Indian control subjects showed that, compared with a Danish control series, they had a significantly higher mean level of IgG, but not of IgA or IgM. By contrast, the IgG levels in eight patients with tropical sprue were decreased or low normal in six cases and raised in only one case.
S. Jarnum, K. N. Jeejeebhoy, B. Singh
openaire   +2 more sources

Faecal biomarkers in children with coeliac disease: A way forward?

Acta Paediatrica, Volume 114, Issue 3, Page 586-593, March 2025.
Abstract Aim Novel markers to reflect the intestinal damage in coeliac disease are needed. We studied the potential of faecal and serum neopterin, and faecal myeloperoxidase, human β‐defensin‐2, and lipocalin‐2 in a case–control study. Methods Data were collected from medical records and a biobank including newly diagnosed coeliac disease patients ...
Laura Kivelä, Monica Atneosen‐Åsegg, Marie Hellan Iversen, Christian Kahrs, Ketil Størdal   +4 more
wiley   +1 more source

Assessment of Intraepithelial Lymphocytes Count in Potential Celiac Disease

APMIS, Volume 133, Issue 3, March 2025.
ABSTRACT Intraepithelial lymphocytes (IELs) count, central for coeliac disease (CD) diagnosis, can be performed either directly on hematoxylin and eosin (H&E)–stained paraffined sections or on optimal‐cutting‐temperature‐compound (OCT)‐embedded frozen sections stained by immunohistochemistry (IHC) with anti‐CD3.
Roberta Mandile, Mariantonia Maglio, Antonella Marano, Luciano Rapacciuolo, Valentina Discepolo, Riccardo Troncone, Renata Auricchio   +6 more
wiley   +1 more source

El cuadro hemático en el sprue

Revista de la Facultad de Medicina, 1944
Resumen de: Review of Gastroenterology: Vol. 9: N° 5: 338-339: Octubre 1942. Virtualmente, todos los casas de sprue que no hayan sido sometidos a tratamiento, muestran anemia.
Howard B. Shookhoff
doaj  

A new algorithm for coeliac disease based on the ‘long forgotten’ TCRγδ+ intra‐epithelial lymphocytes detected with an antibody working on FFPE sections

Histopathology, Volume 86, Issue 3, Page 397-409, February 2025.
The results of the present study highlight a novel discriminant, TCRγδ+ IELs, for coeliac disease with subtle mucosal abnormalities with a diagnostic performance of 93.4%. We therefore propose a diagnostic algorithm based on simple CD3 and TCR δ immunohistochemistry which can easily be integrated into routine pathology practice.
Eda N Kozan, Bilge A Kırmızı, Ceyda T Kirsaclioglu, Derya Gokmen, Berna Savas, Aydan Kansu, Arif I Soykan, Arzu Ensari   +7 more
wiley   +1 more source